Role of the gut microbiota in the pharmacological effects of traditional Kampo medicine and natural products [0.03%]
肠道微生物在汉方药和天然产物的药理作用中的角色
Nobutomo Ikarashi,Risako Kon,Hiroyasu Sakai et al.
Nobutomo Ikarashi et al.
The human gastrointestinal tract harbors over a thousand coexisting bacterial species that together constitute a highly complex intestinal microbiome. Dysbiosis of this microbial ecosystem has been implicated in the pathogenesis of disorder...
Calycosin ameliorates inflammation and M1 macrophage polarization via Spon2 in LPS-triggered MH-S alveolar macrophages [0.03%]
川萼素通过Spon2改善脂多糖诱导的肺泡巨噬细胞炎症和M1极化作用
Gaoyan Chen,Xiaogang Li,Jingyi Zhang et al.
Gaoyan Chen et al.
Acute lung injury (ALI) remains a critical inflammatory condition with limited therapeutic interventions. This study explores the anti-inflammatory potential of calycosin (CAL), a bioactive flavonoid, in lipopolysaccharide (LPS)-induced MH-...
Development of a low-cost, simple, and rapid identification method for Glycyrrhiza uralensis using PCR-RFLP and evaluation of seeds distributed on the market [0.03%]
一种快速简便且低成本的PCR-RFLP法鉴定甘草属植物Glycyrrhiza uralensis Fischer并评价市场上流通的种子种源真实性研究
Tomoyo Nishida,Shinichiro Sawa,Koji Sugimura
Tomoyo Nishida
Glycyrrhiza is a crude drug used worldwide, especially in China and Japan. Glycyrrhiza uralensis Fischer and Glycyrrhiza glabra L. are listed as original plants in the 18th revised Japanese Pharmacopoeia; however, G. uralensis is considered...
Interactions between turnover rate and bioactivity of atractylenolide III in Atractylodes macrocephala rhizome in the theory of crude drugs' pairs and prescriptions in traditional Chinese and Japanese Kampo medicine [0.03%]
基于中日汉方药性理论的白术内酯Ⅲ在苍术中的转化率及其活性关系研究
Pei-Ying Chou,Yung-Jia Chiu,Che-Chun Lin et al.
Pei-Ying Chou et al.
The dried rhizome of Atractylodes macrocephala Koidz. (AM) is widely utilized in traditional Chinese and Japanese Kampo medicine for its therapeutic effects including digestive improvement, spleen strengthening, and dampness reduction. Atra...
Exploring the biological tissue toxicity and related toxic components of Euodiae Fructus through the multi-tissue spectrum-toxicity relationship [0.03%]
基于多组织谱毒关系的吴茱萸药材组织毒性及毒性成分研究
Hao Li,Liansheng Yang,Wenwen Wang et al.
Hao Li et al.
Euodiae Fructus is recorded in ancient Chinese herbal texts as having "small toxicity", with "soup washing" noted as a detoxification method. However, the specific organs affected and the conditions required for detoxification remain unclea...
Optimizing blood-brain barrier permeability: the effect of wine processing on alkaloids in Phellodendri Chinensis Cortex [0.03%]
优化黄柏小檗碱透过血脑屏障的潜力：中药黄柏的不同炮制方法对其有效成分小檗碱透过血脑屏障能力的影响研究
Shuo Zhang,Jiahui Zhao,Wenjing Ren et al.
Shuo Zhang et al.
This study investigated the modification of blood-brain barrier (BBB) permeability of alkaloids from Phellodendri Chinensis Cortex (PC) by wine processing. Phytochemical analysis using UPLC-QqQ-MS compared raw PC (RPC) and wine-processed PC...
Two novel resveratrol dimers from Vatica albiramis: structural elucidation and UV-induced formation [0.03%]
Vatica albiramis中新二聚茋类衍生物的分离鉴定及UV光诱导生成研究
Masashi Fukaya,Kakeru Sugiyama,Kaori Ryu et al.
Masashi Fukaya et al.
Two novel resveratrol dimers, vaticanols O (1) and P (2), were isolated from the bark and stem wood of Vatica albiramis (Dipterocarpaceae), a genus rich in highly oligomerized stilbenoids. Along with seven known constituents, their structur...
New protostane triterpenoids and their bioactivities from the fruits of Schinus terebinthifolius [0.03%]
Schinus terebinthifolius果实施加新型protostane三萜及其生物活性研究
Le-Thuy-Thuy-Trang Hoang,Hoang-Vinh-Truong Phan,Phan-Si-Nguyen Dong et al.
Le-Thuy-Thuy-Trang Hoang et al.
Two new protostane triterpenoids, schifoliusterpenes A and B (1 and 2), were isolated from the fruits of Schinus terebinthifolius. Their structures were elucidated by NMR, HRESIMS, DP4 probability analysis, and comparison with previously re...
New ferrichrome-type siderophores produced by Fusarium lateritium cultured on sodium nitrate-supplemented rice medium [0.03%]
改良培养基中伏革菌产生新型铁载体类黄酮化合物及其抗真菌活性研究
Yuki Hitora,Kensuke Iwakiri,Yusaku Sadahiro et al.
Yuki Hitora et al.
Iron is an essential element for all living organisms, and various microorganisms, such as fungi and bacteria, produce siderophores that chelate iron and facilitate its uptake from the environment. Certain fungi produce ferrichrome-type cyc...
Rapid determination of heavy metals and arsenic in herbal medicines using energy-dispersive X-ray fluorescence spectrometry [0.03%]
采用能量色散X射线荧光法快速测定草药中重金属和砷的含量
Ryoko Arai,Hiroyuki Kamakura,Naoko Masumoto et al.
Ryoko Arai et al.
The Heavy Metals Limit Test in the Japanese Pharmacopoeia is a chemical method used to detect the total amount of heavy metals based on Pb contents. However, determining the amounts of particular metals has become popular since the ICH-Q3D ...