Misoprostol exposure disrupts neural tube development in a chick embryo model: experimental implications for forensic toxicology [0.03%]
米索前列醇暴露通过鸡胚胎模型干扰神经管发育：法医毒理学实验的含义
Ugur Kayhan,Abdülkadir Bilir,Tolga Ertekin et al.
Ugur Kayhan et al.
Purpose: Misoprostol is a uterotonic agent widely used in obstetric and gynecological practice and is of forensic importance due to its involvement in pregnancy termination cases and related medico-legal evaluations. This...
Post-mortem degradation of flunitrazepam by aldehyde oxidase 1 and hemoglobin in blood [0.03%]
血液中氟硝西泮的死后降解：由醛氧化酶1和血红蛋白介导
Yoshikazu Yamagishi,Hiroyuki Inoue,Sayaka Nagasawa et al.
Yoshikazu Yamagishi et al.
Purpose: Flunitrazepam is a widely used hypnotic agent detected in many fatal intoxication and suicide cases. However, its concentration in blood during autopsy differs from that at the time of death; it is either undetec...
An Ultra-High performance liquid chromatography-tandem mass spectrometry method for simultaneous determination of etomidate, analogues, and metabolites in human nail: Unveiling a unique accumulation profile [0.03%]
一种超高效液相色谱-串联质谱方法：同时测定人指甲中依托咪酯、类似物和代谢产物：揭示独特的蓄积特征
Pinting Zhang,Kaiyu Wang,Xinyi Yan et al.
Pinting Zhang et al.
Purpose: In response to the increasing abuse of etomidate-related substances in China, this study developed and validated an ultra-high performance liquid chromatography-tandem mass spectrometry method for the simultaneou...
Volatile organic compounds (VOCs) in femoral muscle from forensic autopsy cases: exploring potential indicators of postmortem ethanol production: Part I - comprehensive profiling of postmortem generated VOCs [0.03%]
法医尸体解剖股二头肌中挥发性有机物（VOCs）的研究：探索潜在的乙醇生成死后指示物：第一部分-综合表征生成的VOCs
Natsuki Ikematsu,Koji Yonemoto,Kenji Ninomiya et al.
Natsuki Ikematsu et al.
Purpose: In postmortem ethanol analysis in decomposed cases, simultaneously detected volatile organic compounds (VOCs) serve as indicators of postmortem ethanol production. Among these, 1‑propanol is the most widely used...
Development of a similarity discrimination method for cannabis samples using Inter-Simple Sequence Repeat-PCR [0.03%]
基于ISSR-PCR的 Cannabis 样品相似性判别方法构建
Tadashi Yamamuro,Yuki Okada,Hiroki Segawa et al.
Tadashi Yamamuro et al.
Purpose: In forensic cannabis investigations, it is important not only to prove that seized materials are cannabis or not but also to clarify the relationship between cannabis samples. This study aimed to establish a meth...
Comparative stability assessment of novel LSD analogs in dry blood spots and blood using UHPLC-MS/MS: implications for forensic applications [0.03%]
一种新型LSD类似物的稳定性评估：基于UHPLC-MS/MS在干血斑和血液中的比较分析及其法医学应用意义
Kaja Tusiewicz,Paweł Szpot,Marcin Zawadzki
Kaja Tusiewicz
Purpose: New LSD analogs are a newly emerging and basically under-researched group of new psychoactive substances (NPS). The emergence of a completely new group of NPS make it difficult to monitor intoxications with these...
Reinventing quaaludes: a comprehensive review of designer methaqualone analogs [0.03%]
重新发明安眠酮：甲喹酮衍生物的全面回顾
Olga Wachełko,Kaja Tusiewicz,Marcin Zawadzki et al.
Olga Wachełko et al.
Purpose: The continuous emergence of NPS has posed a persistent challenge to forensic toxicology for more than a decade. Each year, previously unrecognized compounds appear on the illicit drug market, complicating analyti...
Metabolite patterns in human urine after oral administration of highly purified Δ8-THCV [0.03%]
口服给予高纯度Δ8-四氢大麻酚后人体尿液中的代谢产物模式
Cristina Sempio,Jorge Campos-Palomino,Jelena Klawitter et al.
Cristina Sempio et al.
Introduction: The interest in therapeutic applications of tetrahydrocannabivarin (THCV) recently increased. For this reason, we validated an online extraction liquid chromatography- tandem mass spectrometry (LC-MS/MS) met...
Effects of 4-position substitutions of diphenidine on blood-brain barrier penetration and dopamine release in the nucleus accumbens of rats [0.03%]
4-位取代二苯丁乙胺类化合物的血脑屏障穿透性和对大鼠伏核多巴胺释放的影响
Yuta Takahashi,Katsuhiro Okuda,Kazuo Matsubara et al.
Yuta Takahashi et al.
Purpose: Diphenidine (DPD) is a dissociative novel psychoactive substance (NPS) structurally related to phencyclidine and ketamine. Although DPD is legally regulated in Japan and several other countries, analogues sharing...
Artificial intelligence assisted behavioral profiling of synthetic cannabinoids in planarians [0.03%]
人工智能辅助自由生活模式动物合成大麻素的行为表征技术及其应用研究
Jay R Vargas,Laura L Hernandez,Leo H Lai et al.
Jay R Vargas et al.