Z-Selective semihydrogenation of alkynes via Ni/Lewis acid synergistic catalyzed system using DMF as hydrogen source and solvent [0.03%]
N,N-二甲基甲酰胺作氢源和溶剂的Ni/路易斯酸协同催化炔烃ZH选择性半加氢反应
Lei Kang,Haifeng Gao,Luo Yang
Lei Kang
A Ni/Lewis acid dual-catalytic system has been developed for the Z-selective semihydrogenation of alkynes. Utilizing DMF as both the hydrogen donor and reaction medium, this method affords Z-alkenes in high yield with excellent stereoselect...
Julian Link,Albin Lahu,Manfred Wagner et al.
Julian Link et al.
Spacer length is a key molecular parameter governing the self-assembly of short peptides. Here, we investigate isoleucine-cysteine-alanine (ICA) tripeptides containing carbon spacers of 6, 3, or 0 methylene units linking the peptide backbon...
Veronica Iuliano,Carmen Talotta,Margherita De Rosa et al.
Veronica Iuliano et al.
Electrochemical reduction of unsaturated carbon-carbon bonds via 3d transition-metal catalysis [0.03%]
基于3d过渡金属催化的不饱和碳碳键电化学还原反应
Geon Kang,Minki Jeon,Pooja Kumari Jat et al.
Geon Kang et al.
Electrochemical reduction has emerged as a powerful alternative to conventional hydrogenation for unsaturated C-C bonds, enabling precise control without molecular hydrogen or stoichiometric reductants. This review summarizes recent advance...
Synthesis of sterically shielded piperidine nitroxides via acid-catalyzed heterocyclization of β-aminoketone derivatives with ketones [0.03%]
β-氨基酮衍生物与酮的酸催化杂环化构建受空间位阻保护的哌啶亚硝基化合物
Mark M Gulman,Yurii I Glazachev,Sergey A Dobrynin
Mark M Gulman
The capabilities of modern methods for the synthesis of sterically shielded piperidine nitroxides with acyclic substituents are largely limited to symmetrical tetraethyl structures and do not allow the introduction of functional groups into...
Chiral cyclopropenimine-catalyzed enantioselective Michael reactions of phenol and benzofuran-derived α,β-unsaturated pyrazolamides with benzophenone-imine of glycine esters [0.03%]
联苯甲酰亚胺和α,β-不饱和吡唑酰胺的迈克尔加成反应研究取得进展
Ya Bai,Xue-Ying Wang,Si-Kai Zhu et al.
Ya Bai et al.
The enantioselective Michael reactions of benzophenone-imine of glycine esters with phenol- and benzofuran-derived α,β-unsaturated pyrazolamides have been realized by using a chiral cyclopropenimine (Lambert catalyst, CSB-1) as an organoc...
A practical CO2-mediated synthesis of 5,6-carboxylated silicon-rhodamines for targeted probe development [0.03%]
一种实用的二氧化碳介导合成5,6-羧基硅茋类化合物的方法用于靶向探针开发
Dongjie Hou,Shaowei Wu,Ning Xu et al.
Dongjie Hou et al.
Silicon-rhodamine (SiR) dyes are among the most important fluorophores for super-resolution imaging owing to their far-red emission, high photostability, and tunable lactone-zwitterion equilibrium. However, their broader application in targ...
Palladium-catalyzed benzocyclization reactions of quinoline-2-carboxamides via sequential C-H/N-H functionalization [0.03%]
通过连续的C-H/N-H活化反应合成苯并杂环化合物
Shoichi Sugita,Kentaro Okano,Atsunori Mori
Shoichi Sugita
A novel benzocyclization protocol has been developed for the synthesis of quinoline-fused lactams by palladium-catalyzed sequential C-H/N-H functionalization of quinoline-2-carboxamides and 1,2-dihaloarenes. The reaction proceeds at the C-H...
Cascade transformation of 2-(diazoacetyl)-2 H-azirines to 2-aroyl-3-hydroxy-1 H-pyrroles via condensation with aromatic aldehydes [0.03%]
2-(重氮乙酰基)-2H-恶嗪经芳香醛缩合 cascade 转化为2-芳酰基-3-羟基-1H-吡咯类化合物
Timur O Zanakhov,Ekaterina E Galenko,Mikhail S Novikov et al.
Timur O Zanakhov et al.
The Cs2CO3-induced condensation of 2-(diazoacetyl)-2H-azirines with aromatic aldehydes does not result in the formation of an azirinyl-substituted β-hydroxy-α-diazocarbonyl compound, but is accompanied by a tandem intramolecular cyclizati...
Recent advances in copper-catalyzed direct hydroamination of alkenes with (hetero)aromatic amines [0.03%]
近年来铜催化不饱和键直接与芳胺烃氨化反应的研究进展
Hyejeong Lee,Yunmi Lee
Hyejeong Lee
Nitrogen-containing aromatic amines and aza-heterocycles are ubiquitous motifs in pharmaceuticals and functional materials, making efficient C-N bond formation a fundamental transformation in synthetic chemistry. The direct hydroamination o...