Transition-state aromaticity and its relationship with reactivity in pericyclic reactions [0.03%]
环化反应中的过渡态芳香性及其与反应性的关系
Israel Fernández
Israel Fernández
The influence of transition-state aromaticity on the barrier heights of concerted pericyclic reactions is summarized herein. To this end, selected representative examples ranging from fundamental processes such as Diels-Alder or Alder-ene r...
Formal synthesis of a selective estrogen receptor modulator with tetrahydrofluorenone structure using [3 + 2 + 1] cycloaddition of yne-vinylcyclopropanes and CO [0.03%]
使用炔-乙烯环丙烷和二氧化碳的[3+2+1]环加成构建四氢氟烷类结构的雌激素受体调节剂的全合成研究
Jing Zhang,Guanyu Zhang,Hongxi Bai et al.
Jing Zhang et al.
A formal synthesis of product VI with tetrahydroflurenone structure as selective estrogen receptor modulator has been realized. The Rh-catalyzed [3 + 2 + 1] reaction of yne-vinylcyclopropanes and CO (20 mmol scale, in 87% yield) for buildin...
3-Aryl-2 H-azirines as annulation reagents in the Ni(II)-catalyzed synthesis of 1 H-benzo[4,5]thieno[3,2- b]pyrroles [0.03%]
镍催化下芳基氨基硫
Julia I Pavlenko,Pavel A Sakharov,Anastasiya V Agafonova et al.
Julia I Pavlenko et al.
A high-yielding method for the synthesis of 3-arylbenzo[4,5]thieno[3,2-b]pyrroles has been developed via pyrrole ring annulation to the aromatic benzo[b]thiophene system, using 3-arylazirines as a N‒C=C synthon. The reaction is catalyzed b...
On the aromaticity and photophysics of 1-arylbenzo[ a]imidazo[5,1,2- cd]indolizines as bicolor fluorescent molecules for barium tagging in the study of double-beta decay of 136Xe [0.03%]
关于作为双色荧光分子标记钡的苯并[a]咪唑[5,1,2-cd]吲哚化物芳香性及光物理性质的研究：应用于136氙的双重β衰变研究
Eric Iván Velazco-Cabral,Fernando Auria-Luna,Juan Molina-Canteras et al.
Eric Iván Velazco-Cabral et al.
In this paper, the behavior of a bicolor fluorescent indicator for the detection of barium cations formed by double-beta decay of 136Xe is analyzed by means of computational tools. Both DFT and TDDFT permit to understand the origin of the b...
Ena Kumamoto,Kana Ogawa,Kazunori Okamoto et al.
Ena Kumamoto et al.
Optically active higher-ordered structures, such as one-handed helical and propeller-shaped structures, can be constructed by folding the π-conjugated system using [2.2]paracyclophane as the chiral crossing unit, leading to circularly pola...
pH-Controlled isomerization kinetics of ortho-disubstituted benzamidines: E/ Z isomerism and axial chirality [0.03%]
通过pH控制的对位取代苯甲二胺的异构化动力学：E/Z式异构体和轴手性式异构体
Ryota Kimura,Satoshi Ichikawa,Akira Katsuyama
Ryota Kimura
pH-Responsive molecular switches and motors are a class of organic molecules whose three-dimensional structure can be changed by acid-base stimuli. To date, pH-responsive molecular switches have been developed using various functional group...
Chemical synthesis of glycan motifs from the antitumor agent PI-88 through an orthogonal one-pot glycosylation strategy [0.03%]
通过正交一锅式糖基化策略合成抗肿瘤剂PI-88的寡糖片段
Shaokang Yang,Xingchun Sun,Hanyingzi Fan et al.
Shaokang Yang et al.
Chemical synthesis of monophosphorylated glycan motifs from the antitumor agent PI-88 has been achieved through an orthogonal one-pot glycosylation strategy on the basis of glycosyl ortho-(1-phenylvinyl)benzoates, which not only accelerated...
Thermodynamic equilibrium between locally excited and charge transfer states in perylene-phenothiazine dyads [0.03%]
并苯-苯并噻唑二聚体中局部激发态和电荷转移态的热力学平衡状态研究
Issei Fukunaga,Shunsuke Kobashi,Yuki Nagai et al.
Issei Fukunaga et al.
We report the excited-state dynamics of π-orthogonal donor-acceptor dyads based on perylene (Pe) and phenothiazine (PTZ), in which triphenylamine (TPA) units and a phenyl spacer were introduced to modulate donor strength and spatial separa...
Calcium waste as a catalyst in the transesterification for demanding esters: scalability perspective [0.03%]
钙基废渣催化合成特种酯类脂肪酸甲酯的可行性研究
Anton N Potorochenko,Konstantin S Rodygin
Anton N Potorochenko
Esters are valuable compounds in fine organic synthesis and industry. The significant growth in the demand for esters requires the development of scalable production methods. Heterogeneous CaO-based catalysts for the production of esters by...
Facile synthesis of hydantoin/1,2,4-oxadiazoline spiro-compounds via 1,3-dipolar cycloaddition of nitrile oxides to 5-iminohydantoins [0.03%]
简便的五元氮杂环与氢氨基脲类化合物通过氰基氧化物和亚胺基氢氨基脲的1,3-偶极环加成反应合成螺化合物的方法
Juliana V Petrova,Varvara T Tkachenko,Victor A Tafeenko et al.
Juliana V Petrova et al.
The cycloaddition of 1,3-dipoles at C=N bonds is a relatively rare process, in contrast to the widespread cycloaddition reactions at C=C, C≡C, and C=S bonds. In this study, we present the syntheses of novel hydantoin/1,2,4-oxadiazoline spi...