Matthew E Paolella,Daniel S Honeycutt,Bradley M Lipka et al.
Matthew E Paolella et al.
The CF2H group can act as a hydrogen bond donor, serving as a potential surrogate for OH or SH groups but with a weaker hydrogen bond donation ability. Here, we describe a series of CF2H group-containing moieties that facilitate hydrogen bo...
Nickel-catalyzed cross-coupling of 2-fluorobenzofurans with arylboronic acids via aromatic C-F bond activation [0.03%]
镍催化通过芳香C-F键活化的2-氟苯并呋喃与芳基硼酸的交叉偶联反应
Takeshi Fujita,Haruna Yabuki,Ryutaro Morioka et al.
Takeshi Fujita et al.
2-Fluorobenzofurans underwent efficient nickel-catalyzed coupling with arylboronic acids through the activation of aromatic C-F bonds. This method allowed us to successfully synthesize a range of 2-arylbenzofurans with various substituents....
Sara Colombo,Camilla Loro,Egle M Beccalli et al.
Sara Colombo et al.
This review reports the achievements in copper(II) triflate-catalyzed processes concerning the multicomponent reactions, applied to the synthesis of acyclic and cyclic compounds. In particular, for the heteropolycyclic systems mechanistic i...
Hydrogen-bonded macrocycle-mediated dimerization for orthogonal supramolecular polymerization [0.03%]
氢键型大环介导的二聚体化用于正交超分子聚合
Wentao Yu,Zhiyao Yang,Chengkan Yu et al.
Wentao Yu et al.
Orthogonal self-assembly represents a useful methodology to construct supramolecular polymers with AA- and AB-type monomers, as commonly used for covalently linked polymers. So far, the design of such monomers has relied heavily on three-di...
Recent advances in electrochemical copper catalysis for modern organic synthesis [0.03%]
电化学铜催化在现代有机合成中的最新进展
Yemin Kim,Won Jun Jang
Yemin Kim
In recent decades, organic electrosynthesis has emerged as a practical, sustainable, and efficient approach that facilitates valuable transformations in synthetic chemistry. Combining electrochemistry with transition-metal catalysis is a pr...
Facile one-pot reduction of β-nitrostyrenes to phenethylamines using sodium borohydride and copper(II) chloride [0.03%]
使用氢化钠和氯化铜简便的一锅法将β-亚硝基苯乙烯还原成芳基乙胺
Laura D&#x;Andrea,Simon Jademyr
Laura D&#x;Andrea
Phenethylamines and phenylisopropylamines of scientific relevance can be prepared with a NaBH4/CuCl2 system in 10 to 30 minutes via reduction of substituted β-nitrostyrenes. This one-pot procedure allows the quick isolation of substituted ...
Hot shape transformation: the role of PSar dehydration in stomatocyte morphogenesis [0.03%]
热塑形转化：PS动脉脱水在口腔形态发生中的作用
Remi Peters,Levy A Charleston,Karinan van Eck et al.
Remi Peters et al.
Polysarcosine emerges as a promising alternative to polyethylene glycol (PEG) in biomedical applications, boasting advantages in biocompatibility and degradability. While the self-assembly behavior of block copolymers containing polysarcosi...
Emerging trends in the optimization of organic synthesis through high-throughput tools and machine learning [0.03%]
高通量工具和机器学习在有机合成优化中的新兴趋势
Pablo Quijano Velasco,Kedar Hippalgaonkar,Balamurugan Ramalingam
Pablo Quijano Velasco
The discovery of the optimal conditions for chemical reactions is a labor-intensive, time-consuming task that requires exploring a high-dimensional parametric space. Historically, the optimization of chemical reactions has been performed by...
Henrich Szabados,Radovan Šebesta
Henrich Szabados
Axial chirality is present in a variety of naturally occurring compounds, and is becoming increasingly relevant also in medicine. Many axially chiral compounds are important as catalysts in asymmetric catalysis or have chiroptical propertie...
Chemical glycobiology [0.03%]
化学糖生物学
Elisa Fadda,Rachel Hevey,Benjamin Schumann et al.
Elisa Fadda et al.