Evaluation of [18F]JNJ-CSF1R-1 as a Positron Emission Tomography Ligand Targeting Colony-Stimulating Factor 1 Receptor [0.03%]
[18F]JNJ-CSF1R-1作为靶向集落刺激因子1受体的正电子发射断层显像剂的评估
Mani Salarian,Shuanglong Liu,Hsiu-Ming Tsai et al.
Mani Salarian et al.
Purpose: Colony-stimulating factor 1 receptor (CSF1R) signaling plays a pivotal role in neuroinflammation, driving microglia proliferation and activation. CSF1R is considered a hallmark of inflammation in many neurodegene...
Evaluation of [18F]AlF NOTA-5G, an Aluminum [18F]fluoride Labeled Peptide Targeting the Cell Surface Receptor Integrin Alpha(v)beta(6) for PET Imaging [0.03%]
用于PET成像的放射性铝[18F]氟化物标记多肽[18F]AlF NOTA-5G对细胞表面受体整联蛋白Alpha(v)beta(6)的评估研究
Sven H Hausner,Ryan A Davis,Tanushree Ganguly et al.
Sven H Hausner et al.
Purpose: Peptide-based probes targeting integrin αvβ6 have shown promise in clinical trials for cancer imaging based on the high over-expression of this epithelial-specific cell surface receptor in many cancerous tissue...
Leveraging Radiomics and Hybrid Quantum-Classical Convolutional Networks for Non-Invasive Detection of Microsatellite Instability in Colorectal Cancer [0.03%]
利用放射组学和混合量子经典卷积网络进行非侵入性结直肠癌微卫星不稳定检测
T Buvaneswari,M Ramkumar,Prabhu Venkatesan et al.
T Buvaneswari et al.
Purpose: The goal of this study is to create a novel framework for identifying MSI status in colorectal cancer using advanced radiomics and deep learning strategies, aiming to enhance clinical decision-making and improve ...
Test-retest Assessment of Biventricular Myocardial Oxidative Metabolism and Perfusion in Pulmonary Hypertension Patients Using 11C-acetate PET Imaging: A Pilot Study [0.03%]
肺动脉高压患者心室氧化代谢和血流的测试-重测评估:一种乙酸-11C正电子发射断层扫描成像的试点研究
Ali Ahmadi,Ran Klein,David Gao et al.
Ali Ahmadi et al.
Purpose: 11C-acetate PET is used to measure biventricular oxygen myocardial consumption rate (MVO2) and myocardial blood flow (MBF) changes associated with right ventricular (RV) remodelling. We studied PET reproducibilit...
Optical-magnetic Imaging for Optimizing Lymphodepletion-TIL Combination Therapy in Breast Cancer [0.03%]
乳腺癌淋巴耗竭与TIL联合治疗的光学磁成像优化研究
Jiaqian Li,Lishuang Guo,Yuan Feng et al.
Jiaqian Li et al.
Purpose: Lymphodepletion before tumor-infiltrating lymphocytes (TIL) infusion can activate the immune system, enhance the release of homeostatic cytokines, and decrease the number of immunosuppressive cells. This process ...
DCE-MRI Detects OATP-expressing Transplanted Cells Using Clinical Doses of Gadolinium Contrast Agent [0.03%]
使用临床剂量的钆对比剂检测表达OATP的移植细胞的DCE-MRI研究
Tapas Bhattacharyya,Christiane L Mallett,Jeremy M-L Hix et al.
Tapas Bhattacharyya et al.
Purpose: Hepatic organic anion transporting polypeptides (OATPs) transport off-the-shelf, FDA-approved, hepatospecific Gd-based MRI contrast agents into cells that express the transporters enhancing signal on T1-weighted ...
Autoradiography of Intracerebral Tumours in the Chick Embryo Model: A Feasibility Study Using Different PET Tracers [0.03%]
鸡胚胎模型脑内肿瘤自显影的可行性研究——应用不同的PET示踪剂
Sandra Krause,Alexandru Florea,Chang-Hoon Choi et al.
Sandra Krause et al.
Purpose: In addition to rodent models, the chick embryo model has gained attention for radiotracer evaluation. Previous studies have investigated tumours on the chorioallantoic membrane (CAM), but its value for radiotrace...
PET Imaging of a Transgenic Tau Rat Model SHR24 with [18F]AV1451 [0.03%]
SHR24转基因Tau大鼠模型的[18F]AV1451正电子发射断层扫描影像学研究
Nisha K Ramakrishnan,Annie Ziyi Zhao,Stephen Thompson et al.
Nisha K Ramakrishnan et al.
Purpose: Positron Emission Tomography (PET) scans with radioligands targeting tau neurofibrillary tangles (NFT) have accelerated our understanding of the role of misfolded tau in neurodegeneration. While intended for huma...
Deep Radiogenomics Sequencing for Breast Tumor Gene-Phenotype Decoding Using Dynamic Contrast Magnetic Resonance Imaging [0.03%]
基于动态对比磁共振成像的乳腺肿瘤基因表型解码的深度影像基因组学研究
Isaac Shiri,Yazdan Salimi,Pooya Mohammadi Kazaj et al.
Isaac Shiri et al.
Purpose: We aim to perform radiogenomic profiling of breast cancer tumors using dynamic contrast magnetic resonance imaging (MRI) for the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth fact...