Recent Advances in the Development of CRISPR-Based Live-Cell Molecular Imaging and Sensing [0.03%]
基于CRISPR的活细胞分子成像和传感最新进展
Min Hou,Yulin Li,Xiaobo Wu et al.
Min Hou et al.
Visualizing genome organization and transcriptional dynamics with spatial and temporal precision in living cells is essential for elucidating gene regulation and chromatin-associated disease mechanisms, yet conventional methods confront a f...
Evaluating the Effect of Sorafenib on Gd-EOB-DTPA-mediated Contrast Enhancement: An Experimental Study using DCE-MRI [0.03%]
索拉非尼对Gd-EOB-DTPA介导的对比增强效果的影响：使用动态对比增强MRI进行的实验研究
Yeon Ji Chae,Do-Wan Lee,Chul-Woong Woo et al.
Yeon Ji Chae et al.
Purpose: Despite the potential impact of sorafenib on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-mediated contrast enhancements, attempts to assess these effects are rare. This study aimed t...
Clinical Effectiveness of miR-760 to Distinguish Benign and Malignant Pulmonary Nodules on the Basis of Low-Dose Spiral CT Imaging [0.03%]
基于低剂量螺旋CT影像的miR-760鉴别肺结节良恶性的临床价值研究
Jianwen Chen,Fei Li,Jianguang Chen et al.
Jianwen Chen et al.
Background: The differential diagnosis of benign and malignant pulmonary nodules is a key problem in clinical diagnosis. Low-dose spiral CT (LDCT) is a commonly used screening method, but it has the limitations of insuffi...
Diagnostic Performance of Somatostatin Receptor-directed PET/CT for Tumor-induced Osteomalacia [0.03%]
生长抑素受体显像PET/CT在肿瘤性骨软化诊断中的应用价值评估
Marieke Heinrich,Aleksander Kosmala,Alexander Dierks et al.
Marieke Heinrich et al.
Aim: To evaluate the efficacy of somatostatin receptor (SSTR)-directed PET/CT in localizing phosphaturic mesenchymal tumors (PMT) in patients with suspected tumor-induced osteomalacia (TIO) and to explore relationships be...
Transporter-Mediated Hepatic Uptake of EOB-DTPA and BOPTA Is Largely Independent of Chelated Metal [0.03%]
乙基cyanobenzoate-dipta和boptac的肝摄取与螯合金属无大关系
Legend E Kenney,Christiane L Mallett,Jeremy M-L Hix et al.
Legend E Kenney et al.
Purpose: Metal chelates play a crucial role in diagnostic imaging and radiotherapy. While gadolinium-based chelates are widely used in MRI, radiometal chelates are increasingly used in nuclear medicine and theranostics. D...
Dual Quantification of Skeletal Muscle Perfusion and Metabolism in a Porcine Model of Peripheral Artery Disease Using Multiparametric 18F-FDG PET Imaging [0.03%]
基于18F-FDG正电子发射断层成像的多参数成像法在周围动脉疾病猪模型中同时评估骨骼肌灌注和代谢能力
Ting-Heng Chou,Mahboubeh Nabavinia,Eleanor T Rimmerman et al.
Ting-Heng Chou et al.
Background: A standard imaging strategy for quantifying skeletal muscle perfusion in peripheral artery disease (PAD) does not exist, and the widespread use of PET imaging for this purpose has traditionally been limited by...
Estimation and Correction of the Partial Volume Effect Using Personalized Phantoms of Lymph Node Metastases in Lutetium 177 SPECT/CT Dosimetry [0.03%]
基于 personalised 淋巴结转移素体的177Lu SPECT/CT剂量学中的部分容积效应估算与校正
J R Hinz,T Kuwert,M Beck et al.
J R Hinz et al.
Purpose: This study aims to quantify and to correct for partial volume effect (PVE) in lymph node metastases of prostate cancer (PC) on Lu-177 SPECT images using 3D-printed phantoms of these structures to establish a grou...
Quantitative [18F]PSMA-1007 PET in Treatment Response Monitoring of Brain Metastases from Non-small Cell Lung Cancer [0.03%]
[18F]PSMA-1007 PET在非小细胞肺癌脑转移治疗反应监测中的定量研究
Elisabeth Kirkeby Lysvik,Andreas Julius Tulipan,Vilde Drageset Haakensen et al.
Elisabeth Kirkeby Lysvik et al.
Purpose: Prostate-specific membrane antigen (PSMA) is expressed in several solid tumours, including brain metastases (BMs) from lung cancer. We investigated quantitative [18F]PSMA-1007 uptake and treatment response in BMs...
Accurate Reference Region Calculation in Mouse Brain [18F]fallypride Studies [0.03%]
小鼠脑[18F]fallypride研究中的精确参考区计算
Alan Miranda,Filipe Elvas,Steven Staelens
Alan Miranda
Quantification of the dopamine D2/3 receptors tracer [18F]fallypride is usually performed by defining the cerebellum (CB) as the reference region for its use in kinetic modeling. In mouse studies, [18F]fallypride is defluorinated causing gr...