Feasibility of Early Dynamic 18F-FDG PET/CT Imaging for Predicting EGFR and TP53 Mutations in Lung Adenocarcinoma [0.03%]
早期动态18F-FDG PET/CT显像预测肺癌腺癌EGFR和TP53突变的可行性研究
Ying Zhang,Guobing Liu,Yingying Guan et al.
Ying Zhang et al.
Objective: To investigate the feasibility of early dynamic 2-[18F]-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) imaging in predicting epidermal growth factor receptor (EGFR)...
Validation of Lung [18F]FDG Uptake as a Quantitative PET Biomarker for Influenza-Associated Pulmonary Inflammation [0.03%]
validation of lung [18f]fdg uptake as a quantitative pet biomarker for influenza-associated pulmonary inflammation
Carla Bianca Luena Victorio,Shantanu Gupta,Arun Ganasarajah et al.
Carla Bianca Luena Victorio et al.
Purpose: Influenza (flu) is a respiratory illness caused by lung infection with influenza viruses. This study establishes lung [18F]FDG uptake by PET/CT as an accurate measure of lung inflammation associated with influenz...
A Guide to Ex Vivo Biodistribution Studies with Radiotracers in Rodent Models [0.03%]
放射示踪剂活体外分布研究指南——小鼠模型示例
Surachet Imlimthan,Cesare Berton,Sophie Poty et al.
Surachet Imlimthan et al.
Preclinical biodistribution studies are required at an early stage of radiopharmaceutical development to determine tracer pharmacokinetics in clinically relevant animal models of human diseases. When combined with quantitative analysis from...
Comparative Study of [18F]DPA714 and [18F]FDG PET Tracers in an Experimental Model of Pulmonary Tuberculosis [0.03%]
一种肺结核实验模型中[DPA714和FDG]PET示踪剂的比较研究
M A Stammes,M P M Vierboom,C C Sombroek et al.
M A Stammes et al.
Purpose: Tuberculosis (TB) continues to afflict global health. Therefore, a deeper understanding of the host response mechanisms that underly pathogenesis versus disease control upon infection with Mycobacterium tuberculo...
[18F]FDG-PET/CT Imaging for Response Characterisation of Experimental Melanomas to Anti-PD-L1/Anti-CTLA-4 Immunotherapy [0.03%]
抗PD-L1/CTL治疗实验性黑色素瘤的[F-18]FDG-PET/CT影像学反应特征研究
Melissa J Antons,Sandra Kloiber-Langhorst,Heidrun Hirner-Eppeneder et al.
Melissa J Antons et al.
Purpose: Immune checkpoint inhibition has shown promising results in malignant melanoma, but not all patients respond equally well, necessitating early, accurate monitoring of immunotherapy response. [18F]FDG-PET/CT aids ...
Epithelial Cell Adhesion Molecule Is an Accurate Target for Fluorescence Guided Imaging of Lymph Nodes [0.03%]
上皮细胞黏附分子是淋巴结影像引导的准确靶点
Kelly Anne McGovern,Katherine O Welch,Ryan Krouse et al.
Kelly Anne McGovern et al.
Purpose: Lymph node (LN) excision is critical in oncologic surgery to provide important therapeutic and diagnostic information. LN evaluation helps in staging cancers, predicting prognosis and improving survival. The ulti...
Detection of Prostate Cancer Metastases During Pelvic Lymph Node Dissection with the PSMA-Targeted Fluorescent Agent OTL78: A Phase II Study [0.03%]
PSMA靶向荧光剂OTL78在盆腔淋巴结清扫术中检测前列腺癌转移灶的II期研究
Judith A Stibbe,Daan F G Linders,Robin A Faber et al.
Judith A Stibbe et al.
Purpose: This study aimed to assess the feasibility of intraoperative fluorescence imaging using the PSMA-targeted fluorescent tracer OTL78 for detecting lymph node metastases during pelvic lymph node dissection (PLND) in...
Metabolic Shift Mirrors GBM Immunity to Anti-PD-L1 Immunotherapy: A Deuterium MRS Study [0.03%]
复发胶质母细胞瘤代谢改变及抗PD-L1免疫治疗效果氘MRI研究
Joel R Garbow,Xia Ge,Tanner M Johanns et al.
Joel R Garbow et al.
Background/objectives: Immune checkpoint blockade (ICB) therapy has been ineffective in glioblastoma (GBM) that recurs following standard-of-care resection and chemoradiation of the primary tumor. Herein, we investigate w...
Peptide Receptor Radionuclide Therapy with Lu-177-DOTATATE and Monitoring with Somatostatin Receptor PET/CT in Patients with Advanced Differentiated Thyroid Carcinoma [0.03%]
卢干扰素-DOTATATE肽受体放射性核素治疗及生长抑素受体PET/CT监测在分化型甲状腺癌进展期患者中的应用
Sophie Carina Kunte,Vera U Wenter,Adrien Holzgreve et al.
Sophie Carina Kunte et al.
Purpose: Peptide receptor radionuclide therapy (PRRT) with Lu-177-DOTATATE is an established treatment option for neuroendocrine tumors (NETs) and has been extended to other somatostatin receptor (SSTR)-expressing tumors....
Gold Nanoparticles in Atherosclerosis: A Dual Approach to Diagnosis and Therapy [0.03%]
金纳米颗粒在动脉粥样硬化诊断和治疗中的双重作用研究
Elaheh Mirhadi,Prashant Kesharwani,Vasily N Sukhorukov et al.
Elaheh Mirhadi et al.
Atherosclerosis (AS) is a chronic condition defined by the accumulation of plaque fundamentally resulting from the deposition of low-density lipoprotein and fibrous compounds within injured arteries. Current treatments for atherosclerosis a...