3'-Deoxy-3'-[18F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models [0.03%]
3'-脱氧-3'-[18F]氟胸腺嘧啶的摄取与各种实验性肿瘤模型中胸苷磷酸化酶表达的关系
Sonja Schelhaas,Kathrin Heinzmann,Davina J Honess et al.
Sonja Schelhaas et al.
Purpose: We recently reported that high thymidine phosphorylase (TP) expression is accompanied by low tumor thymidine concentration and high 3'-deoxy-3'-[18F]fluorothymidine ([18F]FLT) uptake in four untreated lung cancer...
In Vivo MR Imaging of Dual MRI Reporter Genes and Deltex-1 Gene-modified Human Mesenchymal Stem Cells in the Treatment of Closed Penile Fracture [0.03%]
闭合性阴茎骨折治疗中双报告基因及Deltex-1基因修饰的人骨髓间充质干细胞的体内MR成像研究
Ruomi Guo,Qingling Li,Fei Yang et al.
Ruomi Guo et al.
Purpose: The purpose of this study was to investigate the feasibility of dual magnetic resonance imaging (MRI) reporter genes, including ferritin heavy subunit (Fth) and transferrin receptor (TfR), which provide sufficien...
In vivo Biodistribution of Radiolabeled Acoustic Protein Nanostructures [0.03%]
放射性标记声学蛋白纳米结构的体内分布特性研究
Johann Le Floc&#x;h,Aimen Zlitni,Holly A Bilton et al.
Johann Le Floc&#x;h et al.
Purpose: Contrast-enhanced ultrasound plays an expanding role in oncology, but its applicability to molecular imaging is hindered by a lack of nanoscale contrast agents that can reach targets outside the vasculature. Gas ...
Heike E Daldrup-Link
Heike E Daldrup-Link
This commentary summarizes insights and discussions about the status of women leaders in STEM (science, technology, engineering, and medicine). While many academic institutions now train close to 50 % female students in STEM disciplines, th...
A PSMA Ligand Labeled with Cobalt-55 for PET Imaging of Prostate Cancer [0.03%]
一种用于前列腺癌PET显像的55钴标记PSMA配体
Johan Hygum Dam,Birgitte Brinkmann Olsen,Christina Baun et al.
Johan Hygum Dam et al.
Purpose: Prostate-specific membrane antigen (PSMA) comprises a recognized target for molecular imaging of prostate cancer. As such, radiolabeled PSMA inhibitors are of great value for diagnosis and staging of this disease...
Potential Effect of Prolonged Sevoflurane Anesthesia on the Kinetics of [11C]Raclopride in Non-human Primates [0.03%]
长时间异氟醚麻醉对非人灵长类[11C]氯胺酮药代动力学潜伏影响的初步研究
Ryosuke Arakawa,Lars Farde,Junya Matsumoto et al.
Ryosuke Arakawa et al.
Purpose: Positron emission tomography (PET) in non-human primates (NHP) is commonly performed under anesthesia, with sevoflurane being a widely used inhaled anesthetic. PET measurement in NHP can be repeated, and a differ...
An Automated Multidose Synthesis of the Potentiometric PET Probe 4-[18F]Fluorobenzyl-Triphenylphosphonium ([18F]FBnTP) [0.03%]
用于电位PET探针4-[18F]氟代苄基三苯基磷([18F]FBnTP)的自动化多剂量合成
Christopher M Waldmann,Adrian Gomez,Phillip Marchis et al.
Christopher M Waldmann et al.
Purpose: The aim of this study was the automated synthesis of the mitochondrial membrane potential sensor 4-[18F]fluorobenzyl-triphenylphosphonium ([18F]FBnTP) on a commercially available synthesizer in activity yields (A...
[18F]DPA-714 PET Imaging Reveals Global Neuroinflammation in Zika Virus-Infected Mice [0.03%]
DPA-714正电子发射断层扫描显像显示寨卡病毒感染小鼠出现全球性神经炎症
Kyle Kuszpit,Bradley S Hollidge,Xiankun Zeng et al.
Kyle Kuszpit et al.
Purpose: The association of Zika virus (ZIKV) infection and development of neurological sequelae require a better understanding of the pathogenic mechanisms causing severe disease. The purpose of this study was to evaluat...
Effects of Long-Term Caffeine Consumption on the Adenosine A1 Receptor in the Rat Brain: an In Vivo PET Study with [18F]CPFPX [0.03%]
长期摄取咖啡因对大鼠脑腺苷A1受体的影响：[18F]CPFPX的在体PET研究
Danje Nabbi-Schroeter,David Elmenhorst,Angela Oskamp et al.
Danje Nabbi-Schroeter et al.
Purpose: Caffeine, a nonselective antagonist of adenosine receptors, is the most popular psychostimulant worldwide. Recently, a protective role of moderate chronic caffeine consumption against neurodegenerative diseases s...
Evaluation of [99mTc]Radiolabeled Macrophage Mannose Receptor-Specific Nanobodies for Targeting of Atherosclerotic Lesions in Mice [0.03%]
评价放射性示踪剂[99mTC]标记的纳米抗体 targeting 动脉粥样硬化斑块中的巨噬细胞甘露糖受体的功效
Gezim Bala,Henri Baudhuin,Isabel Remory et al.
Gezim Bala et al.
Purpose: Macrophage accumulation characterizes the development of atherosclerotic plaques, and the presence of certain macrophage subsets might be an indicator of plaque phenotype and (in)stability. The macrophage mannose...