2-[18F]Fluoropropionic Acid PET Imaging of Doxorubicin-Induced Cardiotoxicity [0.03%]
二氟丙酸PET显像评估多柔比星致心肌毒性的动物研究
Juan A Azcona,Anja S Wacker,Chul-Hee Lee et al.
Juan A Azcona et al.
Purpose: Treatment of pediatric cancers with doxorubicin is a common and predictable cause of cardiomyopathy. Early diagnosis of treatment-induced cardiotoxicity and intervention are major determinants for the prevention ...
Evaluation of Inflammatory Activity of Extraocular Muscles in Thyroid Associated Orbitopathy by [68Ga]DOTATATE PET/CT [0.03%]
68镓-DOTATATE PET/CT在评估甲状腺相关眼病的肌炎中的价值研究
Zhengquan Hu,Jinyan Liu,Haoyu Deng et al.
Zhengquan Hu et al.
Purpose: The accurate assessment of inflammatory activity of the extraocular muscles (EOMs) in thyroid associated ophthalmopathy (TAO) is crucial for formulating subsequent treatment strategies and prognostic judgments. T...
Oral Administration of [18F]MC225 for Quantification of P-glycoprotein Function: A Feasibility Study [0.03%]
[~{}]口服给药用于量化P-糖蛋白功能的可行性研究
Giordana Salvi de Souza,Cristiane R G Furini,Jürgen W A Sijbesma et al.
Giordana Salvi de Souza et al.
Purpose: This preclinical study explored the feasibility of assessing P-glycoprotein (P-gp) function in both brain and gastrointestinal (GI) tract of rats using positron emission tomography (PET) following oral administra...
18F-FAPI-42 PET/CT and 18F-FDG PET/CT in Patients with Malignant Digestive System Neoplasms: A Head-to-Head Comparative Study [0.03%]
18F-FAPI-42和18F-FDG正电子发射断层扫描/计算机断层扫描在恶性消化系统肿瘤中的比较研究
Min Xiong,HongJi You,Jingmin Feng et al.
Min Xiong et al.
Purpose: Radionuclide-labeled fibroblast activation protein inhibitor (FAPI) is an emerging tumor tracer. We sought to assess the uptake and diagnostic performance of 18F-FAPI-42 PET/CT compared with simultaneous 2-deoxy-...
PET Imaging of Sphingosine-1-Phosphate Receptor 1 with [18F]TZ4877 in Nonhuman Primates [0.03%]
TZ4877的18F-PET imaging非人灵长类动物中S1P1受体的体内成像
Jiwei Gu,Ming-Qiang Zheng,Daniel Holden et al.
Jiwei Gu et al.
Purpose: The sphingosine-1-phosphate receptor-1 (S1PR1) is involved in regulating responses to neuroimmune stimuli. There is a need for S1PR1-specific radioligands with clinically suitable brain pharmcokinetic properties ...
Eman Akam-Baxter,Christine M O&#x;Brien,Sanhita Sinharay et al.
Eman Akam-Baxter et al.
The imposter phenomenon (IP) is a destructive set of beliefs, traits, and experiences in which high-achieving individuals fail to internalize their accomplishments and falsely perceive themselves as frauds. IP is a function of underrepresen...
Evaluation of Brain Impairment Using Proton Exchange Rate MRI in a Kainic Acid-Induced Rat Model of Epilepsy [0.03%]
基于KA致痫大鼠模型的氢质子交换速率MRI评价脑损伤效应研究
Huanhuan Yang,Qiting Wu,Lin Li et al.
Huanhuan Yang et al.
Purpose: Proton exchange rate (Kex) is a valuable biophysical metric. Kex MRI may augment conventional structural MRI by revealing brain impairments at the molecular level. This study aimed to investigate the feasibility ...
68Ga-pentixafor PET/CT Is a Supplementary Method for Primary Aldosteronism Subtyping Compared with Adrenal Vein Sampling [0.03%]
68镓- pentixafor PET/CT是辅助原发性醛固酮增多症分型的补充方法与肾上腺静脉取样相比
Tieci Yi,Difei Lu,Yonggang Cui et al.
Tieci Yi et al.
Purpose: To investigate the diagnostic efficacy of 68Ga-pentixafor positron emission tomography/computed tomography (PET/CT) in primary aldosteronism (PA) subtyping and lateralization of aldosterone secretion in PA patien...
68Ga-PSMA PET/CT-Based Model Predicts Perineural Invasion of Prostate Cancer with Whole-Mount Sections [0.03%]
基于68Ga-PSMA PET/CT的模型通过整张切片预测前列腺癌的神经周围浸润
Jie Gao,Yao Fu,Kuiqiang He et al.
Jie Gao et al.
Purpose: To develop a novel risk model incorporating 68Ga-PSMA PET/CT parameters for prediction of perineural invasion (PNI) of prostate cancer (PCa). Met...
Ex Vivo Human Tissue Functions as a Testing Platform for the Evaluation of a Nerve-Specific Fluorophore [0.03%]
体外人组织作为评估神经特异性荧光团的测试平台
Logan M Bateman,Samuel S Streeter,Kendra A Hebert et al.
Logan M Bateman et al.
Significance: Selecting a nerve-specific lead fluorescent agent for translation in fluorescence-guided surgery is time-consuming and expensive. Preclinical fluorescent agent studies rely primarily on animal models, which ...