Nonlinearity arising from noncooperative transcription factor binding enhances negative feedback and promotes genetic oscillations [0.03%]
非协同作用转录因子结合所引起的非线性增强负反馈并促进基因振荡
Ivan M Lengyel,Daniele Soroldoni,Andrew C Oates et al.
Ivan M Lengyel et al.
We study the effects of multiple binding sites in the promoter of a genetic oscillator. We evaluate the regulatory function of a promoter with multiple binding sites in the absence of cooperative binding, and consider different hypotheses f...