In silico based exploration of natural and synthetic antidiabetic compounds: A comprehensive review of computational approaches [0.03%]
基于计算的天然和合成抗糖尿病化合物的研究:计算方法综述
Ahmad Fariz Maulana,Sriwidodo Sriwidodo,Iman Permana Maksum et al.
Ahmad Fariz Maulana et al.
Background and purpose: Diabetes mellitus type 2 is a global health issue marked by hyperglycemia and metabolic dysfunction. Despite progress, discovering safe and effective antidiabetic agents remains crucial. This revie...
Rosanoid diterpenoids: structural diversity, classification and biological activities [0.03%]
玫瑰烷二萜类化合物:结构多样性、分类及生物活性
Sabrin R M Ibrahim,Hani Z Asfour,Gamal A Mohamed et al.
Sabrin R M Ibrahim et al.
Background and purpose: Rosanoid diterpenoids, including ent-rosane and rosane diterpenoids, are structurally unique and bioactive subclass diterpenes characterized by a tricyclic carbon skeleton. This work aims to provid...
Novel stirring method for small-scale dissolution test: Rotating vessel method [0.03%]
新型小规模溶出试验搅拌方法:回转容器法
Shiori Ishida,Samuel Lee,Balint Sinko et al.
Shiori Ishida et al.
Background and purpose: In the compendial dissolution test, the overhead rotating paddle method (ORP) has been used for stirring, whereas the magnetic stirring bar method (MSB) has been employed for small-scale dissolutio...
Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions [0.03%]
精准治疗非瘢痕性脱发:系统基因组和通路靶向干预框架
Rinky Kapoor,Depti Bellani,Raji Patil et al.
Rinky Kapoor et al.
Background and purpose: Non-scarring alopecia, principally androgenetic alopecia and alopecia areata is highly prevalent and psychologically burdensome; androgenetic alopecia is androgen-driven, whereas alopecia areata is...
Anti-infective macrozones: design, biological evaluation and structure-activity relationships [0.03%]
抗感染大区域:设计、生物评估和结构活性关系
Tomislav Jednačak,Višnja Stepanić,Iva Habinovec et al.
Tomislav Jednačak et al.
Background and purpose: To discover novel compounds active against sensitive and resistant bacterial strains, a series of novel azithromycin-thiosemicarbazone conjugates, the macrozones, have been synthesized and their bi...
Electrochemical sensing and quantification of theobromine in cocoa products at polyvaline functionalized graphite paste sensor electrode [0.03%]
聚缬氨酸功能化石墨糊传感器电极上巧克力产品中茶碱的电化学传感和定量检测
Battira Madappa Sharmila,Jamballi G Manjunatha
Battira Madappa Sharmila
Background and purpose: Theobromine (THB), an alkaloid present in various plants, is widely used in pharmaceutical formulations and food products. Increased consumption leads to health risks in both humans and animals. ...
Development of a carbon paper-based electrochemical immunosensor for trimethoprim detection in fishery species: monitoring antibiotic contaminants [0.03%]
一种用于检测渔业品种中三甲氧苄氨嘧啶的碳纸电化学免疫传感器的发展:监测抗生素污染物
Maria Freitas,Vitória Dibo,Rita Ribeiro et al.
Maria Freitas et al.
Background and purpose: Monitoring antibiotic drugs in the environment is particularly relevant given their role in fostering microbial resistance, impacting aquatic species and human health. Therefore, this work addresse...
ZnO-modified carbon paste electrode for electrochemical sensing of dopamine in the presence of tyrosine [0.03%]
一种新型的ZnO修饰碳糊电极用于酪氨酸存在下多巴胺的电化学检测研究
Ali Obaid Imarah,Nada Hasan,Mustafa G Alabbasi
Ali Obaid Imarah
Background and purpose: Dopamine, 3,4-dihydroxyphenylalanine, functions as a catecholamine neurotransmitter in the brain, sending messages to other neurons to regulate information transmission to other areas of the brain,...
Electrochemical detection of chloramphenicol using gadolinium tungstate with sulphur-doped carbon nitride nanocomposite [0.03%]
用于氯霉素电化学检测的硫掺杂碳氮化物- gadolinium tungstate纳米复合材料
Trishul Alanahally Mallu,Gagankumar Sakleshpur Kumar,Santhosh Arehalli Shivamurthy et al.
Trishul Alanahally Mallu et al.
Background and purpose: Chloramphenicol (CAP) is a broad-spectrum antibiotic whose unregulated presence in pharmaceuticals and food products raises significant health concerns, underscoring the need for rapid, reliable de...
Efficient electrochemical determination of dopamine in the presence of uric acid in real samples using tungsten disulfide nanostructure modified electrode [0.03%]
使用二硫化钨纳米结构修饰电极高效电化学测定实际样品中尿酸共存时的多巴胺含量
Ibrahim Ayad Jihad,Thekrayat Joodi Jassim,Zainab Naeif Mageed
Ibrahim Ayad Jihad
Background and purpose: Research on the detection of uric acid (URA) and dopamine (DPA) is ongoing because of the difficulties posed by their closely overlapping oxidation potentials. Tungsten disulfide nanostructures hav...