Potential of extracellular vesicles from human Wharton's jelly and golden berries (Physalis peruviana) combined with polyvinyl alcohol/chitosan/fibroin hydrogel for wound healing: In vitro approaches on 1BR3 cell line [0.03%]
Afrida Rizky Nurfajrin,Indra Wibowo,Anggraini Barlian
Afrida Rizky Nurfajrin
Background and purpose: The development of biocompatible delivery systems capable of enhancing wound healing remains a major challenge in drug delivery and regenerative medicine. Hydrogels represent promising wound dressi...
Graphene-supported Pd/Pt nano-catalysts for enhanced colorimetric detection of dopamine and NADH using paper-based microfluidic devices [0.03%]
Ruri Agung Wahyuono,Jovin Jovin,Ignacius Gilbert Chano et al.
Ruri Agung Wahyuono et al.
Background and purpose: Dopamine and nicotinamide adenine dinucleotide (NADH) are key biomarkers associated with neurological and metabolic disorders. Developing rapid, low-cost, and portable detection platforms of these ...
Linking biomimetic binding measurements to pharmacokinetic models of volume of distribution and hepatic clearance [0.03%]
Klara Valko
Klara Valko
Background and purpose: The steady-state volume of distribution reflects the extent to which drugs partition between plasma and tissues and is closely related to the tissue-to-plasma partition coefficient. In pharmacokine...
High-sensitivity electrochemical immunosensor for anti-SARS-CoV-2 IgG detection using screen-printed carbon/cerium oxide-gold electrode [0.03%]
Melania Janisha Devi,Ratu Shifa Syafira,Shabarni Gaffar et al.
Melania Janisha Devi et al.
Background and purpose: Serological assays are essential for evaluating immune responses, including donor screening, vaccine efficacy, and antibody persistence. However, conventional methods are time-consuming and require...
Modelling an alternative lipophilicity scale of bisphenols using biomimetic chromatography: Relevance to membrane-driven baseline toxicity [0.03%]
Krzesimir Ciura,Julia Nicman,Szymon Zdybel et al.
Krzesimir Ciura et al.
Background and purpose: Bisphenol A and its structural analogues are ubiquitous environmental contaminants and potential endocrine disruptors, creating a need for mechanistically relevant descriptors that support early ha...
Neuroprotective cellular and molecular mechanisms of physical exercise on neurodegenerative diseases [0.03%]
Saswati Swagatika Sahoo,Pratap Kumar Sahu,Nishigandha Sa et al.
Saswati Swagatika Sahoo et al.
Background: Neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's disease are characterized by a progressive loss of neuronal function and loss of synaptic capacity. Physical exercise (PE) is one o...
Simultaneous quantification of drug and coformer during cocrystal dissolution using in situ UV spectroscopy and multicomponent analysis [0.03%]
Shiori Ishida,Samuel Lee,Balint Sinko et al.
Shiori Ishida et al.
Background and purpose: The primary objective of this study was to assess the feasibility of applying in situ UV spectroscopy in combination with multicomponent analysis (MCA) to simultaneously quantify the dissolution of...
Plantain peel extract-mediated synthesis of CuO nanoparticles: comprehensive characterization, bioinertness in vitro and in vivo, and anticancer evaluation [0.03%]
Srimathi JaganMoorthy,Pranav Raaj Subbarayan Ravichandar,Harini Ganesan et al.
Srimathi JaganMoorthy et al.
Background and purpose: Cancer is one of the leading causes of death worldwide, failing to identify a complete cure. Liver cancer is the sixth most frequent cancer worldwide, and its cure is still not assured. Nanoparticl...
Mortality prediction with adjuvant tamoxifen in breast cancer: Machine learning-integrated explainable artificial intelligence and Bayesian model results [0.03%]
Kannan Sridharan,Gowri Sivaramakrishnan
Kannan Sridharan
Background and purpose: Tamoxifen is a cornerstone of adjuvant endocrine therapy for breast cancer, yet significant inter-individual variability in treatment response and mortality exists. Identifying robust predictors of...
Liposome-mediated gene delivery: A comprehensive review of biophysical parameters, lipid composition and targeting strategies [0.03%]
脂质体介导的基因传递：生物物理参数、脂质组成和靶向策略综述
Erfan Jafari Saleh,Mohammad Satari,Behnam Hajipour-Verdom
Erfan Jafari Saleh
Background and purpose: Gene therapy has emerged as a transformative strategy for treating genetic and acquired disorders, but its clinical success relies heavily on the development of safe, efficient, and target-specific...