Comparative effects of pravastatin and rosuvastatin on carbohydrate metabolism in an experimental diabetic rat model [0.03%]
普伐他汀和罗苏伐他汀对糖尿病大鼠糖代谢影响的比较研究
Hacer Kayhan Kaya,Berjan Demirtas,Beran Yokus et al.
Hacer Kayhan Kaya et al.
Statin treatment may increase the risk of diabetes; there is insufficient data on how statins affect glucose regulation and glycemic control and the effects of statins on liver enzymes related to carbohydrate metabolism have not been fully ...
Novel (±)- trans- β-lactam ureas: Synthesis, in silico and in vitro biological profiling [0.03%]
新型(±)-trans-β-内酰胺脲类化合物：合成与体外生物活性研究
Mladenka Jurin,Višnja Stepanić,Krunoslav Bojanić et al.
Mladenka Jurin et al.
A diastereomeric mixture of racemic 3-phthalimido-b-lactam 2a/2b was synthesized by the Staudinger reaction of carboxylic acid activated with 2-chloro-1-methylpyridinium iodide and imine 1. The amino group at the C3 position of the b-lactam...
Furanocoumarin compounds isolated from Dorstenia foetida potentiate irinotecan anticancer activity against colorectal cancer cells [0.03%]
从Dorstenia foetida中分离的呋喃香豆素化合物可增强鸢尾素的抗癌活性以对抗结直肠癌细胞
Supusson Pengnam,Watcharapa Jitkaroon,Roongtiwa Srisuphan et al.
Supusson Pengnam et al.
Although the anticancer activity of Dorstenia foetida was already observed, the chemical entity responsible for this activity remained unidentified. In this study, the cytotoxic activity of two furanocoumarin compounds, i.e., 5-methoxy--3-(...
Characterization of mineral composition of leaves and flowers of wild-growing Sambucus nigra [0.03%]
野生长在的桑巴库斯尼格拉叶和花的矿物成分特征分析
Bujar Qazimi,Trajče Stafilov,Katerina Bačeva Andonovska et al.
Bujar Qazimi et al.
The objective of this study was to determine the mineral content in the leaves and flowers of wild-grown Sambucus nigra collected from eleven different locations in Kosovo. The samples were digested in a microwave system using the wet diges...
The impact of cryoprotectant exposure time on post-thaw viability of autologous and allogeneic hematopoietic stem cells and leukocyte subpopulations [0.03%]
冷冻保护剂作用时间对自体和同种异体造血干细胞及白细胞亚群解冻后活力的影响
Vladimira Rimac,Ines Bojanić,Sanja Dabelić et al.
Vladimira Rimac et al.
Although the use of cryoprotectant dimethyl sulfoxide (DMSO) is the gold standard in cryopreservation of hematopoietic stem cells, it is well known that it has a negative effect on cell viability. The aim of this prospective study was to ex...
Oleuropein in olive leaf, branch, and stem extracts: stability and biological activity in human cervical carcinoma and melanoma cells [0.03%]
橄榄叶、树枝和茎提取物中的欧酪酐：在人宫颈癌和黑色素瘤细胞中的稳定性和生物活性
Đani Benčić,Monika Barbarić,Ana Mornar et al.
Đani Benčić et al.
Olive leaves as a main byproduct of olive oil and fruit industry are a valuable source of phytochemicals such as polyphenols, with multiple biomedical effects. Apart from leaves, olive branches and stems make up a significant amount of oliv...
Synthesis, antiproliferative and antiplasmodial evaluation of new chloroquine and mefloquine-based harmiquins [0.03%]
新的氯喹和甲氟喹为基础的紫杉醇衍生物的合成及其抗增殖和抗疟疾活性评估
Kristina Pavić,Goran Poje,Lais Pessanha De Carvalho et al.
Kristina Pavić et al.
Here we present the synthesis and evaluation of the biological activity of new hybrid compounds, ureido-type (UT) harmiquins, based on chloroquine (CQ) or mefloquine (MQ) scaffolds and β-carboline alkaloid harmine against cancer cell lines...
Exploring adherence in patients with advanced breast cancer: focus on CDK4/6 inhibitors [0.03%]
探索晚期乳腺癌患者的依从性：重点讨论CDK4/6抑制剂
Matea Baković,Martina Bago,Lucija Benić et al.
Matea Baković et al.
Treatment adherence is crucial for optimal outcomes in advanced breast cancer, but can be challenging due to various factors, i.e. patients' attitudes and behavior upon diagnosis, and complex therapies with high adverse effect rates. Our ai...
Preparation of astaxanthin/zeaxanthin-loaded nanostructured lipid carriers for enhanced bioavailability: Characterization-, stability-and permeability study [0.03%]
虾青素/叶黄素负载纳米结构脂质载体的制备以提高生物利用度：特性、稳定性和渗透性研究
Kristina Radić,Ana Isabel Barbosa,Salette Reis et al.
Kristina Radić et al.
Astaxanthin (ASTA) and zeaxanthin (ZEA) are xanthophyll carotenoids showing a wide spectrum of health-promoting properties. However, their utilization is limited, mostly due to poor water solubility, limited bioavailability, and a tendency ...
Beliefs about medicines' association with endocrine therapy adherence in early breast cancer survivors in Croatia [0.03%]
早期乳腺癌幸存者对药物与内分泌治疗依从性关联的信念研究（克罗地亚）
Ana Dugonjić Okroša,Tajana Silovski,Natalija Dedić Plavetić et al.
Ana Dugonjić Okroša et al.
This observational, cross-sectional study conducted at the University Hospital Centre Zagreb (UHC Zagreb) aimed to explore patients' beliefs about adjuvant endocrine therapy (AET) as well as their association with non-adherence and sociodem...
Observational Study
Acta pharmaceutica (Zagreb, Croatia). 2023 Dec 26;73(4):673-689. DOI:10.2478/acph-2023-0043 2023