Antibacterial and antibiofilm activities of naturally occurring naphthoquinones 2-hydroxy-1,4-naphthoquinone and 2-methoxy-1,4-naphthoquinone against Escherichia coli [0.03%]
天然产物菲醌2-羟基-1,4-菲醌和2-甲氧基-1,4-菲醌对大肠杆菌的抗菌和抗生物被膜活性
Darija Stupin Polančec,Dafinë Kastrati Bajçinca,Ana-Marija Domijan
Darija Stupin Polančec
The aim of this study was to evaluate the antibacterial and antibio-film potential of two naturally occurring naphthoquinones, 2-hydroxy-1,4-naphthoquinone (2-HNQ) and 2-methoxy-1,4-naphthoquinone (2-MNQ), against the Gram-negative bacteriu...
Motility, biofilm, and endotoxin in Ralstonia pickettii isolates obtained from purified and ultrapure pharmaceutical water systems [0.03%]
不动性、生物被膜和内毒素的产生在来源于注射用水和纯蒸汽制药水系统的伯克霍尔德氏菌中的分布研究
Ivanka Batarilo,Branka Bedenić,Mia Slade-Vitković et al.
Ivanka Batarilo et al.
This study aimed to examine the motility, biofilm production, endotoxin release, and antibiotic resistance of 81 Ralstonia pickettii isolates collected from different pharmaceutical water systems in Croatia. Swimming and twitching motility ...
Application of green analytical principles in the HPLC analysis of prednisolone derivatives: Method optimization and validation for nasal powder formulations [0.03%]
绿色分析原理在HPLC测定皮质激素鼻粉剂中应用及方法学研究
Daniela Amidžić Klarić,Jelena Kovačić,Ilija Klarić et al.
Daniela Amidžić Klarić et al.
Glucocorticoids are a group of drugs increasingly used in modern medical practice due to their pronounced anti--inflammatory and immunosuppressive properties. In this study, prednisolone disodium phosphate and prednisolone acetate were anal...
Double-blind randomised controlled trial of an emollient cream with and without 1 % supercritical CO2 extract of Calendula officinalis in contact dermatitis [0.03%]
含1%Calendula officinalis超临界CO₂萃取物的润肤霜治疗接触性皮炎的双盲随机对照试验
Mia Šušak Crnčević,Toni Durdov,Doris Rušić et al.
Mia Šušak Crnčević et al.
This double-blind randomised controlled trial aimed to evaluate the efficacy of an emollient cream with and without 1 % supercritical CO2 extract of Calendula officinalis in contact dermatitis. Twenty healthy volunteers without pre-existing...
Randomized Controlled Trial
Acta pharmaceutica (Zagreb, Croatia). 2026 Jan 13;75(4):699-708. DOI:10.2478/acph-2025-0035 2026
Investigating preeclampsia risk factors and angiogenic profiles in low-screening area [0.03%]
低筛查地区子痫前期的风险因素及血管生成特征研究
Adriana Bokulić,Dražan Butorac,Ivka Djaković et al.
Adriana Bokulić et al.
Preeclampsia (PE) is a complex pregnancy disorder that may cause adverse outcomes for mother and baby. Combining risk factors with clinical, laboratory, and ultrasonographic data can help identify women at risk. This study investigated the ...
Impact of clinical pharmacist counselling at discharge on adherence to oral antibiotics: A pilot study [0.03%]
临床药剂师关于出院时口服抗生素治疗的用药教育对患者依从性影响的一项试点研究
Katarina Vilić,Mirna Momčilović,Darija Kuruc Poje et al.
Katarina Vilić et al.
Antibiotic resistance is a growing global health threat, with patient non-adherence to prescribed antibiotic regimens representing an important contributing factor. This prospective interventional study investigated the impact of clinical p...
Randomized Controlled Trial
Acta pharmaceutica (Zagreb, Croatia). 2026 Jan 13;75(4):643-657. DOI:10.2478/acph-2025-0039 2026
The hidden impact of COVID-19 treatment strategies on the spread of Clostridioides difficile infection [0.03%]
COVID-19治疗策略对艰难梭菌感染传播的隐性影响
Ivana El Hassouni,Martin Kondža,Ivan Tomić et al.
Ivana El Hassouni et al.
The COVID-19 pandemic introduced substantial changes to clinical practice, including widespread antibiotic use. These changes raised concerns about a potential rise in healthcare-associated infections, particularly Clostri dioi des difficil...
Observational Study
Acta pharmaceutica (Zagreb, Croatia). 2026 Jan 13;75(4):673-685. DOI:10.2478/acph-2025-0037 2026
MARS-5 vs. MARS-10: Optimizing pharmacist-led adherence assessment in clinical heart failure practice [0.03%]
MARS-5与MARS-10：临床心力衰竭实践中药师主导的依从性评估的优化
Mirna Momčilović,Iva Bužančić,Boško Skorić et al.
Mirna Momčilović et al.
Optimising medication adherence is essential for effective heart failure (HF) management, yet nonadherence remains common, particularly among hospitalised and advanced-stage patients. This study evaluated the internal consistency reliabilit...
Peptide chirality and opioid receptor modulation: Hepatoprotective effect of d-Met-enkephalin in acetaminophen-induced liver injury [0.03%]
肽类手性和阿片受体调节：d-蛋氨酸脑啡肽在对乙酰氨基酚致肝损伤中的保护作用
Petra Turčić,Roko Martinić,Nikola Štambuk et al.
Petra Turčić et al.
l-Met-enkephalin is a neuropeptide known to exert protective effects in various experimental models of autoimmune and inflammatory diseases. These effects are mediated through opioid receptors and can be abolished by the opioid receptor ant...
Antioxidant activity of methyl caffeate: Evidence of proton-coupled electron transfer reaction mechanism [0.03%]
甲基咖啡酸抗氧化活性：质子偶联电子转移反应机制的证据
Ana Karković Marković,Viktor Pilepić,Cvijeta Jakobušić Brala et al.
Ana Karković Marković et al.
Methyl caffeate (MC), a naturally occurring methyl ester of caffeic acid (CA), exhibits potent antioxidant activity and a broad spectrum of biological effects. This study investigates the antioxidant mechanism of MC through its reaction wit...