Comparative efficacy and safety of vedolizumab and antitumor necrosis factor alfa in patients with inflammatory bowel diseases: A meta-analysis [0.03%]
vedolizumab与抗肿瘤坏死因子alfa治疗炎症性肠病的疗效和安全性的对比：一项荟萃分析研究
Yafang Li,Jin Ding,Chong Lu et al.
Yafang Li et al.
This meta-analysis directly compares the efficacy and safety of vedolizumab and tumor necrosis factor-α (TNF-α) inhibitors for patients with inflammatory bowel disease (IBD), contrary to the previous one which provided an indirect compari...
Marijan Marijan,Lejsa Jakupović,Lovorka Vujić et al.
Marijan Marijan et al.
Biowaste produced in urban parks is composed of large masses of organic matter that is only occasionally used economically. In this work, extracts of six plants widely distributed in urban parks in Central Europe (Achillea millefolium, Cich...
Prevalence and factors associated with potential clinically significant drug-drug interactions in patients with cardiovascular diseases at hospital admission [0.03%]
心血管疾病住院患者潜在具有临床意义的药物相互作用及其影响因素分析
Iva Marović,Mario Udovičić,Diana Rudan et al.
Iva Marović et al.
Cardiovascular diseases (CVDs) are the leading cause of mortality and morbidity globally. It is estimated that 17.9 million people died from CVDs in 2019, which represents 32 % of all deaths worldwide. Cardiovascular drugs are the most comm...
Optimization of the suspension procedure by Box-Behnken design for the determination of manganese, iron, and zinc in zeolite clinoptilolite with the TXRF system and insight into its antioxidant properties [0.03%]
基于Box-Behnken设计的悬液过程优化方案及其与抗氧化特性的关系——用TXRF系统测定clinoptilolit沸石中的锰、铁和锌含量
Jasna Jablan,Maja Bival Štefan,Dario Paler et al.
Jasna Jablan et al.
Zeolites are a large family of minerals and the most studied is the naturally occurring clinoptilolite. They possess anti-inflammatory, antioxidant, and detoxifying properties which makes them valuable for medicinal use. Element analysis of...
The impact of blood lipids and statins on renal function and mortality in patients with diabetic nephropathy: A meta-analysis [0.03%]
血脂和他汀类药物对糖尿病肾病患者肾功能及全因死亡率影响的荟萃分析研究
Dongqin Tian,Qian Chen,Lingli Zeng et al.
Dongqin Tian et al.
The aim of this study is to explore the impact of blood lipids and statins on renal function and all-cause mortality in patients with diabetic nephropathy (DN). PubMed, Embase, Web of Science, and Cochrane Library were systematically search...
Integrating network pharmacology and in vivo model to reveal the cardiovascular protective effects of kaempferol-3- O-rutinoside on heart failure [0.03%]
基于网络药理学和体内模型探讨京尼平苷对心力衰竭心脏保护作用及机制研究
Lu-Qin Guo,Lan Zhou,Sheng-Nan Li et al.
Lu-Qin Guo et al.
Kaempferol-3-O-rutinoside (KR) has an excellent cardioprotective effect, but its mechanism of action is not clear. Network pharmacology was used to predict the signaling pathways, whereas molecular docking was used for preliminary validatio...
Advancements in electron paramagnetic resonance (EPR) spectroscopy: A comprehensive tool for pharmaceutical research [0.03%]
电子顺磁共振(EPR)光谱法在药物研究中的应用及进展
Erim Bešić,Zrinka Rajić,Davor Šakić
Erim Bešić
Electron paramagnetic resonance (EPR) spectroscopy has long been established across various scientific disciplines for characterizing organic radicals, organometallic complexes, protein structures and dynamics, polymerization processes, and...
Cloning, expression, and purification of recombinant AKR1D1 for therapeutic applications [0.03%]
用于治疗的AKR1D1重组克隆、表达及纯化
Kristina Shutevska,Aleksandra Kapedanovska Nestorovska
Kristina Shutevska
AKR1D1, a key enzyme in the aldo-keto reductase superfamily, plays a dual role in both steroid metabolism and bile acid synthesis by catalyzing the NADPH-dependent reduction of carbon-carbon double bonds, specifically converting 3-ketostero...
Phenolic content and antioxidant activity of Croatian and German honey [0.03%]
克罗地亚和德国蜂蜜中的酚类含量及其抗氧化活性
Valerija Vujčić Bok,Ivana Šola,Gordana Rusak et al.
Valerija Vujčić Bok et al.
Since honey has a therapeutic role in the treatment of many diseases, we investigated the content of phenolic compounds and the antioxidant activity in acacia (Robinia pseudoacacia L.), chestnut (Castanea sativa Mill.) and lime-tree (Tilia ...
Complete blood count parameters and inflammation-related biomarkers in patients with colorectal carcinoma [0.03%]
结直肠癌患者的血液参数和炎症生物标志物
Martha Koržinek,Ivana Ćelap,Marija Fabijanec et al.
Martha Koržinek et al.
The aim of this study was to determine whether there are differences in complete blood count parameters (CBC) and inflammation-related biomarkers, MPV/PC, PLR, NLR, LWR, LMR, NMR, and LCR, among patients with colorectal carcinoma (CRC) and ...