Investigating preeclampsia risk factors and angiogenic profiles in low-screening area [0.03%]
低筛查地区子痫前期的风险因素及血管生成特征研究
Adriana Bokulić,Dražan Butorac,Ivka Djaković et al.
Adriana Bokulić et al.
Preeclampsia (PE) is a complex pregnancy disorder that may cause adverse outcomes for mother and baby. Combining risk factors with clinical, laboratory, and ultrasonographic data can help identify women at risk. This study investigated the ...
Impact of clinical pharmacist counselling at discharge on adherence to oral antibiotics: A pilot study [0.03%]
临床药剂师关于出院时口服抗生素治疗的用药教育对患者依从性影响的一项试点研究
Katarina Vilić,Mirna Momčilović,Darija Kuruc Poje et al.
Katarina Vilić et al.
Antibiotic resistance is a growing global health threat, with patient non-adherence to prescribed antibiotic regimens representing an important contributing factor. This prospective interventional study investigated the impact of clinical p...
Randomized Controlled Trial
Acta pharmaceutica (Zagreb, Croatia). 2026 Jan 13;75(4):643-657. DOI:10.2478/acph-2025-0039 2026
The hidden impact of COVID-19 treatment strategies on the spread of Clostridioides difficile infection [0.03%]
COVID-19治疗策略对艰难梭菌感染传播的隐性影响
Ivana El Hassouni,Martin Kondža,Ivan Tomić et al.
Ivana El Hassouni et al.
The COVID-19 pandemic introduced substantial changes to clinical practice, including widespread antibiotic use. These changes raised concerns about a potential rise in healthcare-associated infections, particularly Clostri dioi des difficil...
Observational Study
Acta pharmaceutica (Zagreb, Croatia). 2026 Jan 13;75(4):673-685. DOI:10.2478/acph-2025-0037 2026
MARS-5 vs. MARS-10: Optimizing pharmacist-led adherence assessment in clinical heart failure practice [0.03%]
MARS-5与MARS-10：临床心力衰竭实践中药师主导的依从性评估的优化
Mirna Momčilović,Iva Bužančić,Boško Skorić et al.
Mirna Momčilović et al.
Optimising medication adherence is essential for effective heart failure (HF) management, yet nonadherence remains common, particularly among hospitalised and advanced-stage patients. This study evaluated the internal consistency reliabilit...
Peptide chirality and opioid receptor modulation: Hepatoprotective effect of d-Met-enkephalin in acetaminophen-induced liver injury [0.03%]
肽类手性和阿片受体调节：d-蛋氨酸脑啡肽在对乙酰氨基酚致肝损伤中的保护作用
Petra Turčić,Roko Martinić,Nikola Štambuk et al.
Petra Turčić et al.
l-Met-enkephalin is a neuropeptide known to exert protective effects in various experimental models of autoimmune and inflammatory diseases. These effects are mediated through opioid receptors and can be abolished by the opioid receptor ant...
Antioxidant activity of methyl caffeate: Evidence of proton-coupled electron transfer reaction mechanism [0.03%]
甲基咖啡酸抗氧化活性：质子偶联电子转移反应机制的证据
Ana Karković Marković,Viktor Pilepić,Cvijeta Jakobušić Brala et al.
Ana Karković Marković et al.
Methyl caffeate (MC), a naturally occurring methyl ester of caffeic acid (CA), exhibits potent antioxidant activity and a broad spectrum of biological effects. This study investigates the antioxidant mechanism of MC through its reaction wit...
Comparative biodistribution analysis of umbilical cord mesenchymal stromal cells via different administration routes in rabbit models [0.03%]
兔模型中不同给药途径的脐带间充质干细胞的比较生物分布分析
Liang Xiao,Chunlin Liu,Yuqian Wang et al.
Liang Xiao et al.
Umbilical cord mesenchymal stem cells (UC-MSCs) have shown therapeutic potential in renal diseases due to their homing ability. This study compared the effects of three administration routes (intravenous, local renal injection, and interven...
Sedation management in mechanically ventilated intensive care unit patients: Meta-analysis review [0.03%]
机械通气重症监护病房患者镇静管理的meta分析研究
Fawei Yuan,Dong Liu
Fawei Yuan
Sedation is crucial for managing mechanically ventilated intensive care unit (ICU) patients, but agents differ in their effects. Propofol, benzodiazepines and α₂-agonists are commonly used, yet their comparative impact remains unclear. Th...
Pan-Cdk inhibitor ZK304709 suppresses Cdc20 expression and potentiates the anticancer activity of apcin in HeLa cervical cancer cells [0.03%]
泛CDK抑制剂ZK304709通过下调Cdc20表达增强APC激动剂在HeLa宫颈癌细胞中的抗癌活性
Xiangyang Le,Qingsong Chen,Shuyang Cao et al.
Xiangyang Le et al.
Cell division cycle 20 homologue (Cdc20), a key regulator of the anaphase-promoting complex/cyclosome (APC/C), is frequently overexpressed in human cancers and represents a promising therapeutic target. However, monotherapy targeting Cdc20 ...
Gastrointestinal risk profile of tigecycline, omadacycline and eravacycline: Evidence from the FDA adverse event reporting system [0.03%]
替加环素、奥玛克司汀和厄他培南类抗生素的胃肠风险特征：来自美国食品药品监督管理局不良事件报告系统的证据
Zhu Wang,Guoping Gan,Haiping Yao
Zhu Wang
This study assessed the gastrointestinal (GI) safety profiles of tigecycline, omadacycline, and eravacycline through a retrospective disproportionality analysis of reports submitted to the FDA Adverse Event Reporting System (FAERS) between ...