Effect of bisoprolol on central aortic systolic pressure in Chinese hypertensive patients after the initial dose and long-term treatment [0.03%]
美托洛尔对高血压患者初次给药和长期治疗后中央主动脉收缩压的影响
Weiwei Zeng,Brian Tomlinson
Weiwei Zeng
We conducted a prospective open-label cohort study with the aim of examining the effects of the highly β1-selective agent bisoprolol on central aortic systolic pressure (CASP) after the first dose and after 6 weeks' treatment and whether t...
Development and validation of a novel pre-operative comprehensive prognostic score in esophageal squamous cell carcinoma [0.03%]
食管鳞状细胞癌新型术前综合预后评分系统的建立及验证
Jifeng Feng,Liang Wang,Xun Yang et al.
Jifeng Feng et al.
We herein propose a novel integrative score based on inflammatory and nutritional score, coagulation indicator and tumor marker, named comprehensive prognostic score (CPS), to predict postoperative survival in resectable esophageal squamous...
Randomized Controlled Trial
Bosnian journal of basic medical sciences. 2022 Jun 1;22(3):460-470. DOI:10.17305/bjbms.2021.6350 2022
Inflammatory cells in the ascending aortic aneurysm in patients with type 2 diabetes versus patients with hypertension [0.03%]
糖尿病患者与高血压患者的升主动脉瘤炎性细胞研究
Aleksandra Milutinović,Ruda Zorc-Pleskovič
Aleksandra Milutinović
Aortic aneurysms occur relatively frequently in the ascending thoracic aorta, but are rarely seen in patients with type 2 diabetes. Our aim was to evaluate inflammatory cell infiltration in the ascending aortic aneurysm wall in patients wit...
Construction and validation of a preterm birth risk assessment model using fuzzy analytic hierarchy process [0.03%]
基于模糊层次分析法的早产风险评估模型的构建与验证
Stavroula Barbounaki,Antigoni Sarantaki
Stavroula Barbounaki
Preterm births account for almost 1 million deaths globally. The objective of this study is to develop and evaluate a model that assists clinicians in assessing the risk of preterm birth, using fuzzy multicriteria analysis. The model allows...
Xin-Yue Fan,Zhuo-Fen Deng,Yan-Yan Yan et al.
Xin-Yue Fan et al.
With the continuous development of drug screening technology, new screening methodologies and technologies are constantly emerging, driving drug screening into rapid, efficient and high-throughput development. Microfluidics is a rising star...
Quercetin ameliorates testosterone secretion disorder by inhibiting endoplasmic reticulum stress through the miR-1306-5p/HSD17B7 axis in diabetic rats [0.03%]
石果素通过miR-1306-5p/HSD17B7轴抑制内质网应激改善糖尿病大鼠睾酮分泌紊乱
Di Wang,Yan Li,Qian-Qian Zhai et al.
Di Wang et al.
Testicular damage and testosterone secretion disorder are associated with diabetes mellitus. Quercetin, a common flavonoid, has antioxidant, anti-cancer, and blood sugar lowering effects. Therefore, this study aims to investigate the effect...
Plasma exosome-derived fragile site-associated tumor suppressor as a powerful prognostic predictor for patients with ovarian cancer [0.03%]
基于血浆外泌体的脆弱位点肿瘤抑制基因产物作为卵巢癌患者预后预测标志物
Renjing Hu,Xiaochun Chen,Shiliang Zhang et al.
Renjing Hu et al.
The objective of the study was to investigate the levels of plasma exosome-derived fragile site-associated tumor suppressor (FATS) and evaluate its prognostic predictive ability in ovarian cancer (OC) patients. Exosome-rich fractions were i...
Call for emergency action to limit global temperature increases, restore biodiversity, and protect health [0.03%]
呼吁采取紧急行动限制全球气温上升、恢复生物多样性及保护健康受损人群
Lukoye Atwoli,Abdullah H Baqui,Thomas Benfield et al.
Lukoye Atwoli et al.
Altered molecular pathways and prognostic markers in active systemic juvenile idiopathic arthritis: integrated bioinformatic analysis [0.03%]
活性系统性幼年特发性关节炎的分子途径和预后标志物：综合生物信息学分析
Yi Ren,Hannah Labinsky,Andriko Palmowski et al.
Yi Ren et al.
Systemic juvenile idiopathic arthritis (SJIA) is a severe childhood-onset inflammatory disease characterized by arthritis accompanied by systemic auto-inflammation and extra-articular symptoms. While recent advances have unraveled a range o...
Poorly differentiated clusters and tumor budding are important prognostic factors in colorectal carcinomas [0.03%]
分化差的细胞簇和肿瘤芽生是结直肠癌预后的的重要影响因素
Aura Jurescu,Alis Dema,Adrian Văduva et al.
Aura Jurescu et al.
The aim of our study was to assess the prognostic value of the two new grading systems based on the quantification of tumor budding - TB (GBd) and poorly differentiated clusters - PDCs (PDCs-G) in colorectal carcinomas (CRC). We performed a...