Dynamic microglial activation is associated with LPS-induced depressive-like behavior in mice: An [18F] DPA-714 PET imaging study [0.03%]
小鼠内毒素诱导抑郁样行为与动态微胶质活化有关：[18F]DPA-714正电子发射断层扫描成像研究
Tian Qiu,Jiamei Guo,Lixia Wang et al.
Tian Qiu et al.
Major depressive disorder (MDD) is a highly pervasive, severe psychological condition for which the precise underlying pathophysiology is incompletely understood, although microglial activation is known to play a role in this context. In th...
The association between NOTCH3 expression and the clinical outcome in the urothelial bladder cancer patients [0.03%]
NOTCH3表达与尿路上皮膀胱癌患者临床结局的关系
Ana Ristic Petrovic,Dragana Stokanović,Slavica Stojnev et al.
Ana Ristic Petrovic et al.
Disrupted NOTCH activity is a driving event in urothelial bladder cancer (UBC). After activation by hypoxia, the NOTCH3 receptor participates in tumor cell proliferation, acquisition of the epithelial-mesenchymal transition phenotype, and a...
Whole-exome sequencing reveals rare genetic variations in ovarian granulosa cell tumor [0.03%]
全外显子组测序揭示卵巢颗粒细胞瘤中的罕见基因变异
Seungyeon Kim,Songmi Kim,Seyoung Mun et al.
Seungyeon Kim et al.
Ovarian granulosa cell tumor (OGCT) is a rare ovarian tumor that accounts for about 2-5% of all ovarian tumors. Despite the low grade of ovarian tumors, high and late recurrences are common in OGCT patients. Even though this tumor usually o...
A HALP score-based prediction model for survival of patients with the upper tract urothelial carcinoma undergoing radical nephroureterectomy [0.03%]
基于HALP评分的上尿路尿路上皮癌根治性肾输尿管切除术患者生存预测模型
Xiaomin Gao,Binwei Lin,Qi Lin et al.
Xiaomin Gao et al.
The combination of hemoglobin, albumin, lymphocyte, and platelet (HALP) score has been confirmed as an important risk biomarker in several cancers. Hence, we aimed at evaluating the prognostic value of the HALP score in patients with non-me...
Tumor protein P63 Regulated 1 contributes to inflammation and cell proliferation of cystitis glandularis through regulating the NF-кB/cyclooxygenase-2/prostaglandin E2 axis [0.03%]
肿瘤蛋白P63调控的蛋白质1通过调节NF-кB/环氧化酶-2/前列腺素E2轴促进腺性膀胱炎的炎症和细胞增殖
Tao Hong,Songzhe Piao,Liangxue Sun et al.
Tao Hong et al.
Cystitis glandularis is characterized by chronic inflammation and hyperproliferation of bladder mucosa, and contributes to progression of bladder adenocarcinoma. TPRG1 (Tumor Protein P63 Regulated 1) is related to cellular inflammatory respon...
LncRNA ADAMTS9-AS1 knockdown suppresses cell proliferation and migration in glioma through downregulating Wnt/β-catenin signaling pathway [0.03%]
lncRNA ADAMTS9-AS1敲低通过下调Wnt/β-catenin信号通路抑制胶质瘤细胞增殖和迁移
Chunhui Zhou,Hulin Zhao,Shuiwei Wang et al.
Chunhui Zhou et al.
The long non-coding RNA antisense 1 ADAMTS9-AS1 has been reported to serve as an oncogene or tumor suppressor in several tumors, including colorectal cancer and hepatocellular carcinoma. Nevertheless, the clinical significance and biologica...
Impact of smoking on the incidence and post-operative complications of total knee arthroplasty: A systematic review and meta-analysis of cohort studies [0.03%]
吸烟对全膝关节置换术发病率和术后并发症的影响：队列研究的系统评价和荟萃分析
Yuqi He,Mohamed Omar,Xiaoyuan Feng et al.
Yuqi He et al.
Osteoarthritis and rheumatoid arthritis are the most ubiquitous joint disorders which cause tremendous loss of life quality and impose an economic burden on society. At present, the treatment options for these two diseases comprise non-oper...
MicroRNA-573 inhibits cell proliferation, migration and invasion and is downregulated by PICSAR in cutaneous squamous cell carcinoma [0.03%]
微RNA-573通过PICSAR低表达抑制皮肤鳞状细胞癌的增殖、迁移和侵袭
Yanhua Wang,Shengjian Tang,Jianping Lv
Yanhua Wang
The incidence of cutaneous squamous cell carcinoma (cSCC) has been increasing in recent years. Meanwhile, microRNAs (miRNAs) have been found to play vital roles in various cancers, including cSCC. This study aimed to investigate the express...
Three-dimensional telomere profiles in papillary thyroid cancer variants: A pilot study [0.03%]
乳头状甲状腺癌变的三维端粒谱系：一项初步研究
Aline Rangel-Pozzo,Tinuccia Dettori,Daniela Virginia Frau et al.
Aline Rangel-Pozzo et al.
Besides the two main histologic types of papillary thyroid carcinoma (PTC), the classical PTC (CL-PTC) and the follicular variant PTC (FV-PTC), several other variants are described. The encapsulated FV-PTC variant was recently reclassified ...
Protocatechuic acid as an inhibitor of the JNK/CXCL1/CXCR2 pathway relieves neuropathic pain in CCI rats [0.03%]
原花青素A通过抑制JNK/CXCL1/CXCR2通路缓解CCI大鼠的神经病理性疼痛
Hong-Xia Chang,Yue-Feng Zhao
Hong-Xia Chang
Emerging evidence has shown that protocatechuic acid (PCA) has antioxidant and anti-inflammatory effects. It can alleviate the injury of sciatic nerve, while the mechanism of its therapeutic effect on neuralgia remains unknown . In vivo, ch...