Impact of weak MGMT promoter methylation on the prognosis of patients with newly diagnosed glioblastoma [0.03%]
弱甲基化MGMT启动子对新诊断胶质母细胞瘤患者预后的影响
Bujung Hong,Hind Chaib,Gonzalo Moros et al.
Bujung Hong et al.
Background: In most cases, routine neuropathological analysis can clearly distinguish between methylated and unmethylated MGMT promoters in glioblastoma (GBM). However, some GBMs display weak MGMT promoter methylation. Th...
Saarang Patel,Ryan Holland,Ryan Khanna
Saarang Patel
Leonardo Fiori
Leonardo Fiori
Efficacy and safety of gamma knife radiosurgery in the management of pediatric gliomas: a systematic review and meta-analysis [0.03%]
伽马刀放射外科治疗儿童胶质瘤疗效和安全性的系统评价和meta分析研究
Rudolfh B Arend,Marcelo P Sousa,Daniel M Kieling et al.
Rudolfh B Arend et al.
Background: Pediatric gliomas pose significant treatment challenges due to their location in eloquent areas and the vulnerability of the developing brain to toxicity. Gamma knife radiosurgery (GKRS) has emerged as a minim...
Balancing benefits and risks: bevacizumab's role in postoperative recovery after spinal oncologic neurosurgery [0.03%]
贝伐单抗在脊柱肿瘤神经外科术后恢复中的作用及其利弊平衡研究
Lucas Pari Mitre,Marya E Jassé DE Souza Dias,Rebeca Oliveira DA Silva et al.
Lucas Pari Mitre et al.
Background: Spinal oncologic neurosurgery presents considerable therapeutic challenges. Bevacizumab, a monoclonal antibody targeting VEGF, has shown potential to reduce tumor vascularity and postoperative fibrosis. Howeve...
Neurosurgeons in Italy: results of a national census (2022-2024) [0.03%]
意大利神经外科医师：全国普查结果（2022-2024）
Francesca Vitulli,Maria A Cinalli,Maria R Scala et al.
Francesca Vitulli et al.
Background: A precise understanding of the national neurosurgical workforce is essential for effective healthcare planning and ensuring the long-term sustainability of the specialty. In Italy, the number of newly trained ...
Zeyad Kamar,Emre Koyuncu,Michael J Albdewi et al.
Zeyad Kamar et al.
Introduction: This meta-analysis aimed to compare intraoperative metrics and postoperative outcomes of sacroiliac joint fusions (SIJF) performed under robotic versus non-robotic navigation. ...
Huseyin Erdem Ak
Huseyin Erdem Ak
The management of postoperative pain after brain surgery is challenging due to the vulnerability of neuroanatomic structures and differences in the perception of pain among different individuals. Pain management is essential for the patient...
Time is money: a systematic review of time directed activity based costing in spine surgery [0.03%]
时间就是金钱：脊柱外科手术中以时间为方向的活动制本量成本分析系统综述
Eric Singh,Long DI,Tyler Cardinal et al.
Eric Singh et al.
Introduction: Healthcare costs in the USA have increased without corresponding improvements in patient outcomes, prompting calls for value-based reimbursement models. Accurate cost measurement per episode of care is essen...
Rapid versus gradual weaning of external ventricular drains in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis [0.03%]
动脉瘤性蛛网膜下腔出血外部脑室引流快速撤除与缓慢撤除的系统评价和meta分析
George W Brown,Alexandra Lisitsyna,Mohammad Ashraf et al.
George W Brown et al.
Introduction: Aneurysmal subarachnoid hemorrhage commonly requires external ventricular drain (EVD) insertion. The effect of rapid versus gradual weaning on infection rates, hospital stay, and requirement for ventriculope...