Chronotherapeutics and psychiatry: setting the clock to relieve the symptoms [0.03%]
按时用药与精神病学：设定时钟以缓解症状
Andrew N Coogan,Johannes Thome
Andrew N Coogan
Circadian rhythms are near 24-h cycles in a number of physiological and behavioural parameters and the underpinning circadian timing systems is one of the key homeostatic regulatory systems in mammalian physiology. Many common psychiatric c...
Intelligence moderates impulsivity and attention in ADHD children: an ERP study using a go/nogo paradigm [0.03%]
智力通过调节冲动性及注意缺陷来影响注意缺陷多动障碍儿童的事件相关电位模式
Johannes Buchmann,Wolfgang Gierow,Olaf Reis et al.
Johannes Buchmann et al.
Objectives: If the cardinal symptoms of ADHD - hyperactivity, impulsivity and inattention - are combined with a learning disability (70 ≥ IQ < 85), the question arises whether a child shows hyperkinetic behaviour because...
Translational research approach to biological and modifiable risk factors of psychosis and affective disorders [0.03%]
精神病和情感障碍的生物学及可改变的风险因素的研究途径
B T Baune,J Thome
B T Baune
Objectives: This review summarizes the literature on (molecular-) biological, medical, environmental and modifiable risk factors for psychosis and mood disorders with the view of their suitability for translational resear...
E Bastert,D Schläfke
E Bastert
Present literature states that people with acquired organic brain dysfunctions face problems with attention, executive functions and social interaction. During the past years an increasing number of patients with organic brain disorders hav...
Discovering a new anatomical structure in the brain: implications for neuropsychiatry and therapy [0.03%]
发现大脑中的新解剖结构：对神经精神病学和治疗的意义
Michel Barrot,Johannes Thome
Michel Barrot
Describing new brain structures may open research avenues and improve our knowledge of brain functions and of brain disorders. It may also provide new neuroanatomical targets for treatments. A detailed understanding of neuroanatomy is a pre...
Johannes Thome,Frank Hässler,Vanna Zachariou
Johannes Thome
There is no indication that gene therapy can be applied in psychiatric patients any time soon. However, there are several promising developments on the level of experimental neuroscience indicating that gene therapy approaches have an effec...
Regina Taurines,Manfred Gerlach,Andreas Warnke et al.
Regina Taurines et al.
In children and adolescents, antidepressants are used in the treatment of depressive symptoms and several other psychiatric conditions. In the treatment of mild and moderate depressive symptoms, non-pharmacological approaches such as psycho...
Modern neuroimaging in psychiatry: towards the integration of functional and molecular information [0.03%]
精神疾病中的现代影像学：整合功能与分子信息的新方法
David Linden,Johannes Thome
David Linden
Thirty-five years of psychiatric imaging along traditional diagnostic boundaries have revealed a great deal about the structural and functional brain changes that accompany mental disorders but not produced reliable biomarkers. One reason m...
Johannes Thome
Johannes Thome
The terms "molecular psychiatry" and "translational psychiatry" are frequently used key words of today's scientific community. However, the exact meaning of these terms remains surprisingly unclear. They also seem to be interpreted in diffe...
Gender specific associations of serum levels of brain-derived neurotrophic factor in anxiety [0.03%]
焦虑症患者血清脑源性神经营养因子性别差异及相关性研究
Marc L Molendijk,Boudewijn A A Bus,Philip Spinhoven et al.
Marc L Molendijk et al.
Objectives: Whereas animal models indicate that brain-derived neurotrophic factor (BDNF) plays a role in anxiety-related behaviour, little is known about BDNF in patients with an anxiety disorder. We tested the hypothesis...