Peripheral brain-derived neurotrophic factor in stable love relationships: a study in healthy humans [0.03%]
稳定恋爱关系中的周边脑源性神经营养因子：一项健康人的研究
Donatella Marazziti,Federico Mucci,Riccardo Gurrieri et al.
Donatella Marazziti et al.
Objectives: The study aimed to investigate whether involvement in a stable romantic partnership is associated with differences in peripheral brain-derived neurotrophic factor (BDNF) levels. ...
Kidney function and five types of psychiatric traits/disorders: a bidirectional mendelian randomisation study [0.03%]
遗传学随机对照研究肾脏功能和五种精神病特征/疾病之间的关系
Ying Yu,Min Wen,Yang Meng et al.
Ying Yu et al.
Background: Psychiatric traits/disorders and kidney dysfunction frequently co-occur, yet the causal relationships between them remain unclear. Methods: ...
Increased risk of suicide in substance use disorder: a neurobiological perspective [0.03%]
物质使用障碍中的自杀风险：神经生物学视角
Srinagesh Mannekote Thippaiah,Michael Wang,Madison Ransdell et al.
Srinagesh Mannekote Thippaiah et al.
Objectives: Human actions are inherently driven to reduce unpleasant, aversive experiences through physiological and behavioral adaptations. Addictive substances can temporarily fulfil this need for avoidance when conditi...
Exploring purinergic and inflammatory pathways in bipolar disorder: evidence for diagnostic utility of UA, IL-6, NACHT, P2X7, ADA, XDH, ADO [0.03%]
双相障碍中嘌呤能和炎症途径的研究：尿酸、IL-6、NACHT、P2X7、ADA、XDH、ADO诊断价值的证据
Magda Malewska-Kasprzak,Magdalena Sikorski,Filip Rybakowski et al.
Magda Malewska-Kasprzak et al.
Introduction: Bipolar affective disorder (BD) is a chronic psychiatric illness characterized by alternating manic and depressive episodes. Despite extensive research, its underlying mechanisms remain unclear. Recent studi...
Glutathione antioxidant pathways in patients with schizophrenia: relationship with metabolic syndrome [0.03%]
精神分裂症患者的谷胱甘肽抗氧化通路与代谢综合征的关系研究
Irina A Mednova,Yuliya V Shternis,Elena G Kornetova et al.
Irina A Mednova et al.
Objectives: In light of the frequent co-occurrence of metabolic syndrome (MetS) in schizophrenia and their common links to oxidative stress, the aim of our study was to evaluate glutathione (GSH) metabolism parameters in ...
Variants in TPH2 and ADARB1 genes in completed suicide from the Slovenian population - a follow-up to findings on attempted suicide in the Serbian population [0.03%]
斯洛文尼亚人群中的TPH2和ADARB1基因变异在自杀完成中的作用——对塞尔维亚人群中企图自杀的研究的后续研究
Jelena Karanović,Špela Supej,Iris Šalamon Arčan et al.
Jelena Karanović et al.
Introduction: Suicidal behaviour, including completed suicide and attempted suicide, is affected by genetic factors, involving serotonergic system genes. TPH2 gene encodes tryptophan hydroxylase 2, rate-limiting brain ser...
Beyond first-line antidepressants: lithium, quetiapine, or esketamine? Integrating meta-analyses and preliminary head-to-head evidence [0.03%]
一线抗抑郁药之外：锂、喹硫平还是艾司氯胺酮？元分析和初步对比证据的整合
David Eckert,Siegfried Kasper
David Eckert
Objectives: Treatment-resistant depression (TRD) poses a major challenge in research and clinical practice. Various guidelines recommend different pharmacological approaches. While lithium and second-generation antipsycho...
Cross-national differences in methylphenidate utilization in primarily adult psychiatric inpatients [0.03%]
主要成人精神病住院患者中甲基苯丙胺利用的跨国差异
Bernd Hinney,Simon Jost,Sermin Toto et al.
Bernd Hinney et al.
Objectives: Methylphenidate (MPH) is a stimulant primarily used to treat attention-deficit/hyperactivity disorder (ADHD). This study examined cross-national differences in MPH utilisation among primarily adult psychiatric...
Whole blood mitochondrial DNA copy number in depressed patients with and without a history of adverse childhood experiences: the role of blood cell composition [0.03%]
具有和不具有童年不良经历的抑郁症患者全血线粒体DNA拷贝数：血液细胞组成的角色
Karin de Punder,Sonja Entringer,Dries S Martens et al.
Karin de Punder et al.
Objectives: Adverse childhood experiences (ACE) are a significant risk factor for developing major depressive disorder (MDD) later in life, with mitochondria, key sensors of biological stress signals, emerging as a potent...
Saradindu Banerjee,Shrilaxmi M S,Subhrojyoti Banerjee et al.
Saradindu Banerjee et al.
Objectives: This study aims to explore the potential interconnection among epigenetic alteration, epitranscriptomic modifications, and Major Depressive Disorder (MDD). Additionally, it tries to identify potential therapeu...