Frequencies of CYP2C19 and CYP2D6 gene variants in a German inpatient sample with mood and anxiety disorders [0.03%]
德国住院情绪障碍和焦虑障碍患者中CYP2C19及CYP2D6基因变异的频率研究
Maike Scherf-Clavel,Heike Weber,Stefan Unterecker et al.
Maike Scherf-Clavel et al.
Objectives: Previous results demonstrated that CYP2D6 and CYP2C19 gene variants affect serum concentrations of antidepressants. We implemented a PGx service determining gene variants in CYP2D6 and CYP2C19 in our clinical ...
Lymphoblast transcriptome analysis in 22q11.2 deletion syndrome individuals with schizophrenia-spectrum disorder [0.03%]
22q11.2缺失综合症中患有精神分裂症谱系障碍的个体的淋巴母细胞转录组分析
Elena Michaelovsky,Miri Carmel,Doron Gothelf et al.
Elena Michaelovsky et al.
Objectives: 22q11.2 deletion is the most prominent risk factor for schizophrenia (SZ). The aim of the present study was to identify unique transcriptome profile for 22q11.2 deletion syndrome (DS)-related SZ-spectrum disor...
Copy number variant risk loci for schizophrenia converge on the BDNF pathway [0.03%]
精神分裂症的拷贝数变异风险位点集中在BDNF信号通路中
Friederike Ehrhart,Ana Silva,Therese van Amelsvoort et al.
Friederike Ehrhart et al.
Objectives: Schizophrenia genetics is intricate, with common and rare variants' contributions not fully understood. Certain copy number variations (CNVs) elevate risk, pivotal for understanding mental disorder models. Des...
Assessing the impact of sex on high-frequency repetitive transcranial magnetic stimulation´s clinical response in schizophrenia - results from a secondary analysis [0.03%]
评估性别对精神分裂症高频重复经颅磁刺激临床反应的影响-二次分析结果
Mattia Campana,Thomas Schneider-Axmann,Thomas Wobrock et al.
Mattia Campana et al.
Background: The evidence for repetitive transcranial magnetic stimulation (rTMS) to treat negative symptoms in schizophrenia (SCZ) is increasing, although variable response rates remain a challenge. Subject´s sex critica...
P300 parameters in major depressive disorder: A systematic review and meta-analysis [0.03%]
抑郁症中的P300参数：系统评价和荟萃分析
Mehmet Kemal Arıkan,Reyhan İlhan,Özden Orhan et al.
Mehmet Kemal Arıkan et al.
Objectives: Event-related potential measures have been extensively studied in mental disorders. Among them, P300 amplitude and latency reflect impaired cognitive abilities in major depressive disorder (MDD). The present s...
Mathias De Bock,Pascal Sienaert
Mathias De Bock
Objectives: Corticosteroids are widely prescribed for a variety of medical conditions. Accumulating evidence suggests that their use may be associated with adverse psychiatric effects, including mania. In this systematic ...
Common changes in rat cortical gene expression after antidepressant drug treatment: Impacts on metabolism of polyamines, mRNA splicing, regulation of RAS by GAPs, neddylation and GPCR ligand binding [0.03%]
抗抑郁药治疗后大鼠皮层基因表达的共同变化：对多胺代谢、mRNA剪接、GAPs调控RAS、neddylation和GPCR配体结合的影响
Brian Dean,Elizabeth Scarr
Brian Dean
Objectives: This study sought to identify pathways affected by rat cortical RNA that were changed after treatment with fluoxetine or imipramine. Methods: ...
Serum proteomics analysis of drug-naïve patients with generalised anxiety disorder: Tandem mass tags and multiple reaction monitoring [0.03%]
广泛性焦虑障碍药物初治患者的血清蛋白质组学分析：串联质谱标签和多重反应监测法
Xue Li,Sisi Zheng,Zhengtian Feng et al.
Xue Li et al.
Objectives: The prevalence of generalised anxiety disorder (GAD) is high. However, the underlying mechanisms remain elusive. Proteomics techniques can be employed to assess the pathological mechanisms involved in GAD. ...
Multimodal imaging measures in the prediction of clinical response to deep brain stimulation for refractory depression: A machine learning approach [0.03%]
多模态成像在难治性抑郁症深部脑刺激治疗反应预测中的应用：机器学习方法
Rajamannar Ramasubbu,Elliot C Brown,Pauline Mouches et al.
Rajamannar Ramasubbu et al.
Objectives: This study compared machine learning models using unimodal imaging measures and combined multi-modal imaging measures for deep brain stimulation (DBS) outcome prediction in treatment resistant depression (TRD)...
Glucose-6-phosphate dehydrogenase deficiency and psychotic disorders: A systematic review [0.03%]
葡萄糖-6-磷酸脱氢酶缺乏和精神病障碍：系统性回顾研究
Christopher Gandar,James G Scott,Nicola Warren
Christopher Gandar
Objectives: Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD) is the most common enzymopathy globally. Early studies suggested an association with severe psychotic illness; however, changes to laboratory testing and dia...