Low plasma vascular endothelial growth factor (VEGF) associated with completed suicide [0.03%]
自杀死亡者血浆中血管内皮生长因子(VEGF)水平降低
Josef Isung,Fariborz Mobarrez,Peter Nordström et al.
Josef Isung et al.
Objectives: Immunological differences have previously been associated with depression and suicidal behaviour. Several cytokines have been identified as potentially important in understanding the pathophysiology of mood di...
The potential role of Marginal Structural Models (MSMs) in testing the effectiveness of antidepressants in the treatment of patients with major depression in everyday clinical practice [0.03%]
边际结构模型(MSM)在检测抗抑郁药治疗重度抑郁症患者有效性中的潜在作用
Emanuel Severus,Ilya Lipkovich,Florian Seemüller et al.
Emanuel Severus et al.
Objectives: To better evaluate the effectiveness of antidepressant drugs in the treatment of major depression in clinical practice. Methods: ...
Systematic review and meta-analysis of bifrontal electroconvulsive therapy versus bilateral and unilateral electroconvulsive therapy in depression [0.03%]
系统综述和荟萃分析:前额双侧电休克治疗与双侧或单侧电休克治疗抑郁症的疗效及安全性比较
Ross A Dunne,Declan M McLoughlin
Ross A Dunne
Objectives: Our aim was to perform a meta-analysis of randomized controlled trials comparing efficacy and side effects of bifrontal (BF) ECT to bitemporal (BT) or unilateral (RUL) ECT in depression. ...
Olfactory processing in schizophrenia, non-ill first-degree family members, and young people at-risk for psychosis [0.03%]
精神分裂症、非患病一级亲属及易患精神病青年的嗅觉处理能力
Vidyulata Kamath,Bruce I Turetsky,Monica E Calkins et al.
Vidyulata Kamath et al.
Objectives: While deficits in odor identification and discrimination have been reported in schizophrenia, few studies have examined the relative specificity of these deficits in patients and at-risk youth. ...
An international survey of reported prescribing practice in the treatment of patients with generalised anxiety disorder [0.03%]
国际报告用药做法调查:治疗一般焦虑障碍患者
David S Baldwin,Christer Allgulander,Borwin Bandelow et al.
David S Baldwin et al.
Objective: To gain insight into the experience and practice of psychiatrists in the pharmacological management of patients with generalized anxiety disorder (GAD). ...
A pilot genome wide association and gene expression array study of suicide with and without major depression [0.03%]
自杀伴或不伴有重度抑郁的全基因组关联和基因表达矩阵研究
Hanga Galfalvy,Gil Zalsman,Yung-Yu Huang et al.
Hanga Galfalvy et al.
Objectives: Suicide is partly heritable but the responsible genes have not been identified. We conducted a gene-centric, low coverage single nucleotide polymorphism (SNP) pilot genome-wide association study (GWAS) seeking...
Genetics of serum BDNF: meta-analysis of the Val66Met and genome-wide association study [0.03%]
血清BDNF遗传学:甲硫氨酸66缬氨酰多态性Meta分析及全基因组关联研究
Antonio Terracciano,Maria Grazia Piras,Monia Lobina et al.
Antonio Terracciano et al.
Objectives: Lower levels of serum brain derived neurotrophic factor (BDNF) is one of the best known biomarkers of depression. To identify genetic variants associated with serum BDNF, we tested the Val66Met (rs6265) functi...
Hippocampal integrity and neurocognition in first-episode schizophrenia: a multidimensional study [0.03%]
首次发作的精神分裂症的海马结构和神经认知:一项多维度研究
Alkomiet Hasan,Thomas Wobrock,Peter Falkai et al.
Alkomiet Hasan et al.
Objectives: Impairments in memory and executive function are key components of schizophrenia. These disturbances have been linked to several subcortical and cortical networks. For example, anatomical and functional change...
Siegfried Kasper
Siegfried Kasper
Cholinergic impact on neuroplasticity drives muscarinic M1 receptor mediated differentiation into neurons [0.03%]
胆碱能影响神经可塑性驱动毒蕈碱M1受体介导的分化成为神经元
Jens Benninghoff,Werner Rauh,Victor Brantl et al.
Jens Benninghoff et al.
Objectives: Increasing evidence indicates that canonical neurotransmitters act as regulatory signals during neuroplasticity. Here, we report that muscarinic cholinergic neurotransmission stimulates differentiation of adul...