Emil Kraepelin's habilitation and his thesis: a pioneer work for modern systematic reviews, psychoimmunological research and categories of psychiatric diseases [0.03%]
Emil Kraepelin的升等和论文：现代系统综述、心理免疫学研究以及精神疾病分类的先驱工作
Holger Steinberg,Hubertus Himmerich
Holger Steinberg
Objectives: Although Kraepelin and his oeuvre have been in scientific focus over the past decades, main aspects have still been neglected. Thus the exact circumstances under which and on what topic Kraepelin wrote his hab...
Frank Bellivier,Bruno Etain,Alain Malafosse et al.
Frank Bellivier et al.
Objective: To test for differences in reported age at onset (AAO) of bipolar I affective disorder in clinical samples drawn from Europe and the USA. Metho...
Amniotic fluid inflammatory cytokines: potential markers of immunologic dysfunction in autism spectrum disorders [0.03%]
胎盘炎性细胞因子：自闭症免疫功能障碍的潜在标志物
Morsi W Abdallah,Nanna Larsen,Jakob Grove et al.
Morsi W Abdallah et al.
Objectives: The aim of the study was to analyze cytokine profiles in amniotic fluid (AF) samples of children developing autism spectrum disorders (ASD) and controls, adjusting for maternal autoimmune disorders and materna...
Is neurogenesis relevant in depression and in the mechanism of antidepressant drug action? A critical review [0.03%]
抑郁症发病机制及抗抑郁药作用机制中的神经发生相关性再评价：批判性文献回顾
Siu W Tang,Daiga Helmeste,Brian Leonard
Siu W Tang
Objectives: Major depression is a complex disorder that involves genetic, epigenetic and environmental factors in its aetiology. Recent research has suggested that hippocampal neurogenesis may play a role in antidepressan...
The AKT1 gene is associated with attention and brain morphology in schizophrenia [0.03%]
AKT1基因与精神分裂症患者的注意力及脑形态有关
Kazutaka Ohi,Ryota Hashimoto,Yuka Yasuda et al.
Kazutaka Ohi et al.
Objectives: A meta-analysis of the associations between genetic variants in the AKT1 gene and schizophrenia found that a single nucleotide polymorphism (SNP5; rs2494732) was associated with schizophrenia in Asian populati...
The dopamine receptor D4 7-repeat allele influences neurocognitive functioning, but this effect is moderated by age and ADHD status: an exploratory study [0.03%]
多巴胺受体D4 七重复等位基因影响神经认知功能，但这种影响会因年龄和ADHD状态而不同：一项探索性研究
Marieke E Altink,Nanda N J Rommelse,Dorine I E Slaats-Willemse et al.
Marieke E Altink et al.
Objectives: Evidence suggests the involvement of the dopamine D4 receptor gene (DRD4) in the pathogenesis of ADHD, but the exact mechanism is not well understood. Earlier reports on the effects of DRD4 polymorphisms on ne...
Functions of intronic nucleotide variants in the gene encoding pleckstrin homology like domain beta 2 (PHLDB2) on susceptibility to vascular dementia [0.03%]
血管性痴呆易感基因编码类似鸟嘌呤折叠β-2结构域蛋白的内含子多核苷酸变异功能研究
Sangmi Eom,Chaeyoung Lee
Sangmi Eom
Objectives: A genome-wide association study (GWAS) failed to detect any genetic associations with susceptibility to vascular dementia (VaD) by the Bonferroni multiple test. This study aimed to discover false negative asso...
Light-dependent alteration of serotonin-1A receptor binding in cortical and subcortical limbic regions in the human brain [0.03%]
人脑皮质和次级边缘区域光依赖性5-羟色胺-1A受体结合力的变化
Christoph Spindelegger,Patrycja Stein,Wolfgang Wadsak et al.
Christoph Spindelegger et al.
Objective: Climate, in particular sunshine, influences mood and energy levels, creating a positive upswing of mood on bright, sunny days and negative downswing in cold, dark winter seasons. Higher serotonin transporter av...
Differential effects to CCK-4-induced panic by dexamethasone and hydrocortisone [0.03%]
DEX和HCT对CCK-A似物诱发惊恐的不同作用效应
Cüneyt Demiralay,Holger Jahn,Michael Kellner et al.
Cüneyt Demiralay et al.
Objectives: Peripheral administration of the cholecystokinin (CCK) receptor agonist CCK-4 generates panic and activates the hypothalamic-pituitary-adrenal (HPA) axis. Direct effects at the pituitary and CCK-HPA interactio...
Efficacy and safety of prolonged-release OROS methylphenidate in adults with attention deficit/hyperactivity disorder: a 13-week, randomized, double-blind, placebo-controlled, fixed-dose study [0.03%]
一项针对成人注意缺陷多动障碍患者的试验：缓释型OROS甲基苯丙胺的疗效和安全性——一项为期13周的随机双盲安慰剂对照固定剂量研究
Miguel Casas,Michael Rösler,J J Sandra Kooij et al.
Miguel Casas et al.
Objectives: Methylphenidate (MPH) is effective for adults with attention-deficit/hyperactivity disorder (ADHD). This study aimed to evaluate the efficacy and safety of OROS MPH in adults with ADHD. ...