Optimisation of pharmacotherapy in psychiatry through therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests: focus on antipsychotics [0.03%]
通过治疗药物监测、分子脑成像和药物基因组学检测优化精神病学的药物治疗:重点是抗精神病药物
X M Hart,G Gründer,N Ansermot et al.
X M Hart et al.
Background: For psychotic disorders (i.e. schizophrenia), pharmacotherapy plays a key role in controlling acute and long-term symptoms. To find the optimal individual dose and dosage strategy, specialized tools are used. ...
The European psychiatric association (EPA) - early career psychiatrists committee survey on trainees' and early-career psychiatrists' attitudes towards therapeutic drug monitoring (TDM) use and utility during antipsychotic treatment [0.03%]
欧洲精神病学协会(EPA)——青年精神科医师委员会关于受训者和早期职业精神科医生对治疗药物监测(TDM)在抗精神病治疗中使用和作用的态度调查
Georgios Schoretsanitis,Christoph U Correll,Agorastos Agorastos et al.
Georgios Schoretsanitis et al.
Objectives: This survey assessed psychiatry residents'/early-career psychiatrists' attitudes towards the utility of therapeutic drug monitoring (TDM) of antipsychotics. ...
Stress-relieving properties of a polyherbal blend with Syzygium aromaticum L. and Coffea canephora Pierre ex A. Froehner: A review and bibliometric analysis [0.03%]
肉桂和咖啡豆多药用植物混合物的减压功效:综述与文献计量分析
Nor Hafizah Zakaria,Anis Fadhlina,Hassan Ibrahim Sheikh et al.
Nor Hafizah Zakaria et al.
Objective: Syzygium aromaticum and Coffea canephora are acknowledged for their outstanding antioxidant, anti-inflammatory, and nerve-stimulant properties, showcasing potential in brain protection. Therefore, this study ai...
Neural stem/progenitor cells from olfactory neuroepithelium collected by nasal brushing as a cell model reflecting molecular and cellular dysfunctions in schizophrenia [0.03%]
鼻拭子采集的嗅觉上皮神经干细胞/前体细胞作为反映精神分裂症分子和细胞功能障碍的细胞模型
Carlo Idotta,Mario Angelo Pagano,Elena Tibaldi et al.
Carlo Idotta et al.
Objectives: Neural stem/progenitor cells derived from olfactory neuroepithelium (hereafter olfactory neural stem/progenitor cells, ONSPCs) are emerging as a potential tool in the exploration of psychiatric disorders. The ...
Why circadian rhythmicity matters: Associations between sleep irregularity and mental health conditions during the Covid-19 health crisis [0.03%]
为什么生物钟节律很重要:在新冠疫情期间睡眠不规律与精神健康状况之间的联系
Julien Coelho,Ilaria Montagni,Jean-Arthur Micoulaud-Franchi et al.
Julien Coelho et al.
Objective: To assess the association between sleep irregularity, anxiety, and depression while controlling for other sleep dimensions and using a longitudinal design. ...
Right ventrolateral and left dorsolateral 10 Hz transcranial magnetic stimulation as an add-on treatment for bipolar I and II depression: a double-blind, randomised, three-arm, sham-controlled study [0.03%]
右侧经颅磁刺激联合左侧背外侧重复经颅磁刺激作为双相障碍抑郁发作增效治疗:一项随机、双盲、假刺激对照研究
Tomáš Novák,Lenka Kostýlková,Martin Bareš et al.
Tomáš Novák et al.
Objectives: Despite the clinical importance of bipolar depression (BDE), effective treatment options are still limited. Transcranial magnetic stimulation (rTMS) has proven of moderate efficacy in major depression, but the...
Comment on 'Impact of clozapine on the expression of miR-675-3p in plasma exosomes derived from patients with schizophrenia' [0.03%]
关于“氯氮平对精神分裂症患者血浆外泌体miR-675-3p表达的影响”的讨论
Kyle Hewitt,Xu-Feng Huang
Kyle Hewitt
Sisi Zheng,Sitong Feng,Nan Song et al.
Sisi Zheng et al.
Objectives: Depersonalisation-derealization disorder (DPD) is a dissociative disorder that impairs cognitive function and occupational performance. Emerging evidence indicate the levels of tumour necrosis factor-α and in...
Downregulation of lncRNAs Gomafu, NONMMUT033604.2, and NONMMUT064397.2 in the hippocampus of mice with model of post-traumatic stress disorder [0.03%]
下调节PTSD模型小鼠海马区Gomafu和NONMMUT033604.2及NONMMUT064397.2长链非编码RNA的表达水平
Anastasiya Klimenko,Vasyl Nagibin,Anastasiia Horlova et al.
Anastasiya Klimenko et al.
Objectives: Molecular mechanisms of post-traumatic stress disorder (PTSD) development have been analysed by evaluati-ng changes in the expression level of long non-coding RNA (lncRNA) as a potential biomarker of the disea...
Gut microbiota: A potential player in psychiatric symptoms during COVID-19 [0.03%]
肠道微生物群:在COVID-19期间精神症状的潜在参与者
Zijie Zeng,Weilong Tang
Zijie Zeng
Objectives: This study aims to explore the potential interconnections among gut microbiota, COVID-19 infection, depression and anxiety disorder. Additionally, it tries to assess potential therapeutic interventions that ma...