Executive functioning in adults with borderline personality disorder and first-degree biological relatives [0.03%]
边缘型人格障碍成人及一级生物亲属的执行功能研究
Jacob W Koudys,Anthony C Ruocco
Jacob W Koudys
Objectives: Behavioural dysregulation is a heritable core symptom domain in borderline personality disorder (BPD) that is likely influenced by the integrity of executive functions (EFs). However, the extent to which famil...
Antipsychotic drug treatment of schizophrenia in later life: Results from the European cross-sectional AMSP study [0.03%]
老年期精神分裂症的抗精神病药物治疗:来自欧洲国家横断面AMSP研究的结果
Oliver Zolk,Timo Greiner,Michael Schneider et al.
Oliver Zolk et al.
Objectives: To investigate the relationship between patient age and the selection and dosage of antipsychotic drugs (APDs) for treatment of schizophrenia. We describe age effects for multiple individual APDs, thus allowin...
The neurobiology of childhood trauma-aldosterone and blood pressure changes in a community sample [0.03%]
儿童创伤的神经生物学-社区样本中的醛固酮和血压变化
Jan Terock,Anke Hannemann,Johanna Klinger-König et al.
Jan Terock et al.
Objective: Childhood trauma is an important risk factor for the onset and course of psychiatric disorders and particularly major depression. Recently, the renin-angiotensin-aldosterone system, one of the core stress hormo...
Leukocyte telomere length is not shortened in methamphetamine dependence or methamphetamine-induced psychosis but is increased following traumatic events [0.03%]
苯环丙胺依赖或由苯环丙胺诱发的妄想状态不会使白细胞端粒缩短,但创伤事件会使其延长
Teerayuth Rungnirundorn,Kuakarun Krusong,Rasmon Kalayasiri et al.
Teerayuth Rungnirundorn et al.
Objective: This study aims to examine the effects of methamphetamine (MA) use and dependence and MA withdrawal symptoms on the telomere length and whether shortening of the latter is associated with MA-induced psychosis (...
Newborn differential DNA methylation and subcortical brain volumes as early signs of severe neurodevelopmental delay in a South African Birth Cohort Study [0.03%]
一项南非出生队列研究中新生儿差异性DNA甲基化和皮质下脑体积作为重度神经发育迟缓的早期征兆
Anke Hüls,Catherine J Wedderburn,Nynke A Groenewold et al.
Anke Hüls et al.
Objectives: Early detection of neurodevelopmental delay is crucial for intervention and treatment strategies. We analysed associations between newborn DNA methylation (DNAm), neonatal magnetic resonance imaging (MRI) neur...
Growth factors in anorexia nervosa: a systematic review and meta-analysis of cross-sectional and longitudinal data [0.03%]
厌食症中的生长因子:横断面和纵向数据的系统评价与荟萃分析
Johanna Louise Keeler,Lauren Robinson,Rosemarie Keeler-Schäffeler et al.
Johanna Louise Keeler et al.
Objectives: Growth factors are signalling molecules that play roles in the survival, proliferation, migration, and differentiation of cells. Studies have found alterations in specific growth factors in anorexia nervosa (A...
Effects of testosterone suppression on desire, hypersexuality, and sexual interest in children in men with pedophilic disorder [0.03%]
抑制睾酮对恋童症男性性欲、性亢进和对儿童的性兴趣的影响
Valdemar Landgren,Pontus Olsson,Peer Briken et al.
Valdemar Landgren et al.
Effects of testosterone withdrawal on significant correlates of paedophilic disorder (PeD) are largely unknown. The purpose of this study was to explore in detail the effects of testosterone suppression from degarelix as compared to placebo...
A novel genetic variant potentially altering the expression of MANBA in the cerebellum associated with attention deficit hyperactivity disorder in Han Chinese children [0.03%]
与汉族儿童注意力缺陷多动障碍相关的可能改变MANBA在小脑表达的新基因变异
Xinzhen Chen,Ting Yao,Jinliang Cai et al.
Xinzhen Chen et al.
Objectives: To obtain additional insight into the genetic factors of attention deficit hyperactivity disorder (ADHD). Methods: First, w...
BST-1 as a serum protein biomarker involved in neutrophil infiltration in schizophrenia [0.03%]
精神分裂症中与中性粒细胞浸润相关的血清蛋白生物标志物BST-1
Liang-Jen Wang,Yu-Chi Huang,Pao-Yen Lin et al.
Liang-Jen Wang et al.
Objectives: Schizophrenia is a serious mental illness. The serum protein biomarkers of schizophrenia were explored using isobaric tags for relative and absolute quantitation (iTRAQ) technology. The underlying function of ...
Fabian Streit,Lea Zillich,Josef Frank et al.
Fabian Streit et al.
Objectives: The present study introduces the assessment of depression and depressive symptoms in the German National Cohort (NAKO), a population-based mega cohort. Distribution of core measures, and associations with soci...