Targeted sequencing approach: Comprehensive analysis of DNA methylation and gene expression across blood and brain regions in suicide victims [0.03%]
靶向测序方法：自杀者血液和大脑区域的DNA甲基化及基因表达的综合分析
Katarina Kouter,Tomaž Zupanc,Alja Videtič Paska
Katarina Kouter
Objectives: Epigenetic mechanisms are involved in regulation of many pathologies, including suicidal behaviour. However, the factors through which epigenetics affect suicidal behaviour are not fully understood. ...
Pre-treatment plasma cytokine levels as potential predictors of short-term remission of depression [0.03%]
术前血浆细胞因子水平作为短期抑郁缓解的潜在预测指标
Kiyokazu Atake,Hikaru Hori,Yuki Kageyama et al.
Kiyokazu Atake et al.
Objectives: The response to antidepressants varies significantly among individuals and is difficult to predict before treatment. In this randomised control trial, we explored cytokines that correlate with the therapeutic ...
The assessment of cognitive function in the German National Cohort (NAKO) - Associations of demographics and psychiatric symptoms with cognitive test performance [0.03%]
德国国家队列研究中认知功能的评估——人口统计学信息和精神症状与认知检测表现的关系
Luca Kleineidam,Melina Stark,Steffi G Riedel-Heller et al.
Luca Kleineidam et al.
Objectives: To describe the cognitive test battery of the German National Cohort (NAKO), a population-based mega cohort of 205,000 randomly selected participants, and to examine associations with demographic variables and...
General cognitive ability assessment in the German National Cohort (NAKO) - The block-adaptive number series task [0.03%]
德国国家队列研究（NAKO）中的通用认知能力评估——模块化适应性数字序列任务
Florian Schmiedek,Ulf Kroehne,Frank Goldhammer et al.
Florian Schmiedek et al.
Objectives. Evaluate the block-adaptive number series task of reasoning, as a time-efficient proxy of general cognitive ability in the Level-2 sample of the German National Cohort (NAKO), a population-based mega cohort.Methods. The number s...
Associations of common genetic risk variants of the muscarinic acetylcholine receptor M2 with cardiac autonomic dysfunction in patients with schizophrenia [0.03%]
多巴胺受体D2基因TA-repeat多态性与中国汉族人首发、未服药精神分裂症患者临床症状谱的关系研究
Alexander Refisch,Shoko Komatsuzaki,Martin Ungelenk et al.
Alexander Refisch et al.
Objectives: Decreased vagal modulation, which has consistently been observed in schizophrenic patients, might contribute to increased cardiac mortality in schizophrenia. Previously, associations between CHRM2 (Cholinergic...
Carina Jiang,Henrik Dobrowolny,Dorothee Maria Gescher et al.
Carina Jiang et al.
Objectives: This study aims to find out whether volatile organic compounds (VOCs) from exhaled breath differ significantly between patients with schizophrenia and healthy controls and whether it might be possible to creat...
Novel anti-cytoplasmic antibodies in cerebrospinal fluid and serum of patients with chronic severe mental disorders [0.03%]
慢性严重精神疾病患者脑脊液和血清中新型胞浆抗体的研究
Dominique Endres,Benjamin Pankratz,Sarah Thiem et al.
Dominique Endres et al.
Objectives: There is an emerging role of autoimmune causes related to severe mental disorders (SMD). The clinical approach in patients with chronic SMD and novel anti-central nervous system antibodies is complex. ...
Endocannabinoids and addiction memory: Relevance to methamphetamine/morphine abuse [0.03%]
内源大麻素与成瘾记忆：甲基苯丙胺/吗啡成瘾的关联性研究
Mirmohammadali Mirramezani Alizamini,Yonghui Li,Jian-Jun Zhang et al.
Mirmohammadali Mirramezani Alizamini et al.
Aim: This review aims to summarise the role of endocannabinoid system (ECS), incluing cannabinoid receptors and their endogenous lipid ligands in the modulation of methamphetamine (METH)/morphine-induced memory impairment...
The similar eye movement dysfunction between major depressive disorder, bipolar depression and bipolar mania [0.03%]
抑郁症、躁郁症抑郁期和躁狂期患者的眼动功能障碍相似性研究
Ying Wang,Hai-Long Lyu,Xiao-Han Tian et al.
Ying Wang et al.
Objective: To find eye movement characteristics in patients with affective disorders. Method: The demographic and clinical evaluation d...
Precision-medicine findings from the FACE-SZ cohort to develop motivation-enhancing programs in real-world schizophrenia [0.03%]
来自FACE-SZ队列的精准医学研究结果促进现实世界精神分裂症患者的动机增强项目开发
Théo Korchia,Maud Tastevin,Pierre-Louis Sunhary de Verville et al.
Théo Korchia et al.
Background: In people with schizophrenia, major areas of everyday life are impaired, including independent living, productive activities, social relationships and overall quality of life. Enhanced understanding of factors...