Circulating inflammatory markers, cell-free mitochondrial DNA, cortisol, endocannabinoids, and N-acylethanolamines in female depressed outpatients [0.03%]
抑郁症女性门诊患者的循环炎症标志物、游离线粒体DNA、皮质醇、内源大麻素和N-乙醇酰胺类物质
Alexander Behnke,Anja Maria Gumpp,Roberto Rojas et al.
Alexander Behnke et al.
Objectives: Major depressive disorder (MDD) involves peripheral low-grade pro-inflammatory activity. This multi-biomarker case-control study characterises the proinflammatory status in MDD beyond C-reactive protein (CRP) ...
Could low α-N-acetylgalactosaminidase plasma concentration cause schizophrenia? [0.03%]
血浆α-岩藻糖苷酶浓度低能否导致精神分裂症?
Seda Yılmaz,Pınar Öner
Seda Yılmaz
Objectives: Using a neurodevelopmental approach to examine the aetiology, we predicted an enzyme deficiency to exist at the cellular level and aimed to measure α-N-acetylgalactosaminidase (α-NAGAL) blood levels. ...
Depressive-like phenotype enhances relapse of nicotine seeking after forced abstinence in rats [0.03%]
抑郁样表型可增强尼古丁渴求的诱导及其在大鼠强制戒断期间的复发
Petra Amchova,Jana Ruda-Kucerova
Petra Amchova
Objective: Comorbidity of depression and drug addiction is common, but effective treatment is missing. A rat model combining the olfactory bulbectomy (OBX) model and IV drug self-administration has provided evidence of di...
Long-term cortisol stress response in depression and comorbid anxiety is linked with reduced N-acetylaspartate in the anterior cingulate cortex [0.03%]
长期压力下抑郁症和共病焦虑与脑部相关区域N-乙酰天门冬氨酸水平降低有关
Linda M Bonnekoh,Stephanie Seidenbecher,Katrin Knigge et al.
Linda M Bonnekoh et al.
Objectives: Major Depression (MDD) and anxiety disorders are stress-related disorders that share pathophysiological mechanisms. There is evidence for alterations of glutamate-glutamine, N-acetylaspartate (NAA) and GABA in...
BDNF blood levels after electroconvulsive therapy in patients with mood disorders: An updated systematic review and meta-analysis [0.03%]
心境障碍患者电抽搐治疗后的脑源性神经营养因子血液水平的系统回顾和meta分析更新版
Rebeca Pelosof,Leonardo A Dos Santos,Luis C Farhat et al.
Rebeca Pelosof et al.
Objectives: Studies have suggested Brain-Derived Neurotrophic Factors (BDNF) increase after electroconvulsive therapy (ECT) although they were methodologically limited and enrolled small sample sizes. We aimed at updating...
Consensus paper of the WFSBP task force on cannabis, cannabinoids and psychosis [0.03%]
世界生物精神病学协会大麻、大麻素和精神病学共识指南论文
Deepak Cyril DSouza,Marta DiForti,Suhas Ganesh et al.
Deepak Cyril DSouza et al.
Objectives: The liberalisation of cannabis laws, the increasing availability and potency of cannabis has renewed concern about the risk of psychosis with cannabis. ...
Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce [0.03%]
世界生物精神病学联合会和加拿大情绪及焦虑障碍治疗网络关于使用营养药品和植物药品治疗精神疾病的临床指南:工作组报告
Jerome Sarris,Arun Ravindran,Lakshmi N Yatham et al.
Jerome Sarris et al.
Objectives: The therapeutic use of nutrient-based 'nutraceuticals' and plant-based 'phytoceuticals' for the treatment of mental disorders is common; however, despite recent research progress, there have not been any updat...
Klaus Berger,Marcella Rietschel,Dan Rujescu
Klaus Berger
Large population-based cohort studies offer the chance to assess a broad number of diseases and intermediate phenotypes and to estimate their frequencies in the general population. Because of their large sample size new symptom clusters and...
The assessment of childhood maltreatment and its associations with affective symptoms in adulthood: Results of the German National Cohort (NAKO) [0.03%]
童年虐待的评估及其与成人情绪症状的相关性:德国国家队列研究(NAKO)的结果
Johanna Klinger-König,Fabian Streit,Angelika Erhardt et al.
Johanna Klinger-König et al.
Objectives: Childhood maltreatment affects 20-30% of the German population and is an important risk factor for physical and mental diseases in adult life. This study reports first results of the distribution of childhood ...
Abnormal functional connectivity of brain regions associated with fear network model in panic disorder [0.03%]
恐慌障碍中与恐惧网络模型相关脑区的功能连接异常研究
Shuangyi Zhou,Shanshan Su,Ang Hong et al.
Shuangyi Zhou et al.
Background: Patients with panic disorder (PD) have an abnormal function in brain regions related to fear network is well recognised. However, the traditional fear network model (FNM) which was based on animals' horrible behaviours has been ...