Paraskevi Mavrogiorgou,Florian Seltsam,David Kiefner et al.
Paraskevi Mavrogiorgou et al.
Objectives: Based on previous research, it has been proposed that the development of depressive disorders is related to altered functioning of the serotonergic systems as well as the personality style, including narcissis...
Elevated regional cerebral blood flow in adults with 22q11.2 deletion syndrome [0.03%]
22q11.2缺失综合征成人患者的区域脑血流增高现象
Maurice Pasternak,Zahra Shirzadi,Henk J M M Mutsaerts et al.
Maurice Pasternak et al.
Objectives: Recurrent chromosome 22q11.2 deletions cause 22q11 deletion syndrome (22q11DS), a multisystem disorder associated with high rates of schizophrenia. Neuroanatomical changes on brain MRI have been reported in re...
DNA methylation in people with anorexia nervosa: Epigenome-wide patterns in actively ill, long-term remitted, and healthy-eater women [0.03%]
厌食症患者的DNA甲基化：患病期、长期缓解期女性以及健康饮食女性的表观基因组图谱模式
Howard Steiger,Linda Booij,Lea Thaler et al.
Howard Steiger et al.
Objectives: Recent studies have reported altered methylation levels at disorder-relevant DNA sites in people who are ill with Anorexia Nervosa (AN) compared to findings in people with no eating disorder (ED) or in whom AN...
Brain regions associated with olfactory dysfunction in first episode psychosis patients [0.03%]
首次精神病发作患者的嗅觉障碍相关脑区
Semra Etyemez,Zui Narita,Marina Mihaljevic et al.
Semra Etyemez et al.
Objectives: Olfactory dysfunction is reproducibly reported in psychotic disorders, particularly in association with negative symptoms. The superior frontal gyrus (SFG) has been frequently studied in patients with psychoti...
The habenular volume and PDE7A allelic polymorphism in major depressive disorder: preliminary findings [0.03%]
抑郁症患者 Habenula 体积和 PDE7A 基因多态性的初步研究发现
Lyubomir I Aftanas,Elena A Filimonova,Maksim S Anisimenko et al.
Lyubomir I Aftanas et al.
Objectives: The habenula is a brain structure implicated in depression, yet with unknown molecular mechanisms. Several phosphodiesterases (PDEs) have been associated with a risk of depression. Although the role of PDE7A i...
Metformin attenuates depressive-like behaviour of methamphetamine withdrawal in mice: A mechanistic approach [0.03%]
二甲双胍通过多种机制减轻安非他明戒断小鼠的抑郁样行为
Mir-Jamal Hosseini,Aisan Arabiyan,Sina Mobassem et al.
Mir-Jamal Hosseini et al.
Objectives: Methamphetamine (METH) as a potent psychostimulant drug with a high potency of dependence rate that results in neurotoxicity has become a major drug of abuse in many parts of the world. Unfortunately, there is...
Treatment strategies for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A network meta-analysis of randomised controlled trials [0.03%]
针对复方再摄取抑制剂治疗抵抗的强迫症的治疗方法：随机对照试验的网络meta分析研究
Satish Suhas,Palash Kumar Malo,Vijay Kumar et al.
Satish Suhas et al.
Objectives: Treatment-resistant obsessive-compulsive disorder is a chronic debilitating illness. We conducted a network meta-analysis [NMA] to compare the efficacy of all interventions in SRI-resistant OCD from published ...
Mineralocorticoid receptor agonist aldosterone rescues hippocampal neural stem cell proliferation defects and improves postoperative cognitive function in aged mice [0.03%]
矿物皮质激素受体激动剂醛固酮可挽救老龄小鼠海马神经干细胞增殖缺陷并改善术后认知功能障碍
Xuhong Fan,Zhenyu Zhao,Zixia Huang et al.
Xuhong Fan et al.
Objectives: Hippocampal neurogenesis is closely related to learning and memory, and hippocampal neurogenesis disorders are involved in the development of many neurodegenerative diseases. Mineralocorticoid receptor (MR) pl...
Genome-wide association studies on Northern Italy isolated populations provide further support concerning genetic susceptibility for major depressive disorder [0.03%]
意大利北部孤立人群的全基因组关联研究进一步揭示了重大抑郁症的遗传易感性
Vincenzo Dattilo,Sheila Ulivi,Alessandra Minelli et al.
Vincenzo Dattilo et al.
Objectives: Major depressive disorder (MDD) is a psychiatric disorder with pathogenesis influenced by both genetic and environmental factors. To date, the molecular-level understanding of its aetiology remains unclear. Th...