World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of Alzheimer's disease and other dementias [0.03%]
国际生物精神病学会联盟(WFSBP)发布的阿尔茨海默病及其他痴呆症的生物学治疗指南
Ralf Ihl,Lutz Frölich,Bengt Winblad et al.
Ralf Ihl et al.
Objectives: To define a practice guideline for biological treatment of dementia and to make transparent the development of the guideline connecting the original data with the resulting recommendations. ...
Siegfried Kasper
Siegfried Kasper
Increased density of GAD65/67 immunoreactive neurons in the posterior subiculum and parahippocampal gyrus in treated patients with chronic schizophrenia [0.03%]
慢性精神分裂症患者后部子脑回和邻近海马回中GAD65/67免疫反应性神经元密度增加
Stefanie Schreiber,Hans-Gert Bernstein,Robert Fendrich et al.
Stefanie Schreiber et al.
Objectives: Alterations of glutamic acid decarboxylase (GAD) play a crucial role in schizophrenic pathology. While GAD has been studied in several brain regions, its expression in the posterior hippocampus formation has n...
Haloperidol alters circadian clock gene product expression in the mouse brain [0.03%]
氟哌啶醇可改变小鼠脑内昼夜节律基因产物的表达
Andrew N Coogan,Maria M Papachatzaki,Corinne Clemens et al.
Andrew N Coogan et al.
Objectives: Circadian rhythms are patterns in behavioural and physiological measures that recur on a daily basis and are driven by an endogenous circadian timekeeping system whose molecular machinery consists of a number ...
Unstable EEG-vigilance in patients with cancer-related fatigue (CRF) in comparison to healthy controls [0.03%]
癌症相关疲劳患者与健康对照组的不稳定脑电波-警觉性对比研究
Sebastian Olbrich,Christian Sander,Ina Jahn et al.
Sebastian Olbrich et al.
Objectives: Cancer-related fatigue (CRF) is associated with tiredness and sleepiness. It remains unclear, whether such complaints are associated with neurophysiological signs of sleep proneness or a state of neurophysiolo...
Common SNPs in CSF2RB are associated with major depression and schizophrenia in the Chinese Han population [0.03%]
CSF2RB中的常见SNPs与中国汉族人群的重大抑郁症和精神分裂症相关性研究
Peng Chen,Ke Huang,Guoquan Zhou et al.
Peng Chen et al.
Objectives: Colony stimulating factor 2 receptor β (CSF2RB) encodes the protein which is the common β chain of the high affinity receptor for IL-3, IL-5 and CSF. It locates in the linkage region 22q12.3 of both bipolar ...
Serum brain-derived neurotrophic factor: determinants and relationship with depressive symptoms in a community population of middle-aged and elderly people [0.03%]
血浆脑源性神经营养因子的决定因素及其与中老年人群抑郁症状的关系
Boudewijn A A Bus,Indira Tendolkar,Barbara Franke et al.
Boudewijn A A Bus et al.
Objectives: Brain-derived neurotrophic factor (BDNF) is involved in major depressive disorder and neurodegenerative diseases. Clinical studies, showing decreased serum BDNF levels, are difficult to interpret due to limite...
Reduced negative BOLD responses in the default-mode network and increased self-focus in depression [0.03%]
抑郁症患者默认网络负BOLD信号减弱和自我关注增强
Simone Grimm,Jutta Ernst,Peter Boesiger et al.
Simone Grimm et al.
Objectives: Functional imaging studies in major depressive disorder (MDD) indicate abnormal resting state neural activity and negative blood oxygenation level-dependent (BOLD) responses (NBRs) in regions of the default-mo...
Dopaminergic system genes in childhood aggression: possible role for DRD2 [0.03%]
多巴胺能系统基因与儿童攻击性行为的关系：DRD2基因的可能作用
Clement C Zai,Sahar Ehtesham,Esther Choi et al.
Clement C Zai et al.
Excessive or deficient levels of extracellular dopamine have been hypothesized to contribute to a broad spectrum of mood, motor, and thought abnormalities, and dopaminergic system genes have been implicated in aggressive behaviour from anim...
Multimodal psychodynamic psychotherapy induces normalization of reward related activity in somatoform disorder [0.03%]
多模式心理动力学心理治疗可改善躯体化障碍患者的回报相关脑区活动异常
Moritz de Greck,Lisa Scheidt,Annette F Bölter et al.
Moritz de Greck et al.
Objectives: Somatoform disorder patients demonstrate a disturbance in the balance between internal and external information processing, with a decreased focus on external stimulus processing. We investigated brain activit...