Bruton's Tyrosine Kinase: A Potential Novel Target for Neurological Disorders [0.03%]
布鲁顿酪氨酸激酶：神经性疾病潜在的新靶点
D Das,A Ghosh,D Greco et al.
D Das et al.
Bruton's tyrosine kinase (BTK) is a crucial part of the B-cell receptor signaling pathway that has been extensively studied in various types of malignancies. Recent studies have extended our knowledge on its role in metabolism as well as ne...
D Rapaka,A Saniotis,M Henneberg et al.
D Rapaka et al.
Oligodendrocytes are vital for the functioning of the nervous system. Oligodendrocyte-created myelin sheaths work as dynamic partners which play a substantial role in the myelination of axons. In addition to its well-known functions of prov...
Q Shi,L Zhu,L Zhang et al.
Q Shi et al.
Transmembrane Protein 138 (TMEM138) is a transmembrane protein belonging to the superfamily of transmembrane proteins. Recent research has unveiled its involvement in various biological processes such as cell proliferation, differentiation,...
Iodine Intake and Iodine Status in the Czech Republic - Past, Present, Future [0.03%]
捷克的碘摄入及现状与未来展望
R Bílek
R Bílek
The physical and chemical properties of iodine, the importance of iodine for human health, iodine deficiency in the world and in Europe, the cycle of iodine in nature, values of iodine concentration in urine describing iodine deficiency, an...
Thyroid-Stimulating Hormone: An Important Target for the Prevention of Nonalcoholic Fatty Liver Disease [0.03%]
促甲状腺激素：防治非酒精性脂肪肝的重要靶点
Z Wang,H Wang,H Sun
Z Wang
Non-alcoholic fatty liver disease (NAFLD) is one of the leading causes of cirrhosis and liver cancer. Its global prevalence increases annually, significantly affecting quality of life. Only a few patients manage to alleviate NAFLD through l...
J Kovář,R Poledne
J Kovář
Metabolic-dysfunction associated steatotic liver disease (MASLD) affects approximately 30 % of the world adult population and even contributes to the increased mortality from cardiovascular disease. Dietary intervention, along with exercise...
WITHDRAWAL Monitoring of Caffeine Consumption Effect on Skin Blood Properties by Diffuse Reflectance Spectroscopy [0.03%]
咖啡因摄入对皮肤血液属性影响的离散反射光谱监测研究
M Milanic,R Hren,J Stergar et al.
M Milanic et al.
Matija MILANIC1,2, Rok HREN1,3,4, Jost STERGAR1,2, Urban SIMONCIC1,2 1Faculty of Mathematics and Physics, University of Ljubljana, Ljubljana, Republic of Slovenia, 2Jožef Stefan Institute, Ljubljana, Republic of Slovenia, 3Institute of Mat...
Efficacy of Rhythmic Photic Stimulation for Autonomic Nervous System Regulation in University Students [0.03%]
节奏光照刺激对大学生自主神经系统调节的有效性
S-Y Yang,P-C Wang,C-M Chen et al.
S-Y Yang et al.
University students frequently encounter stress and anxiety, impacting their autonomic nervous system and mental health. Rhythmic photic stimulation (RPS) at various frequencies is considered a potential intervention for anxiety and depress...
Utilizing Hyperbaric Oxygen Therapy to Improve Cognitive Function in Patients With Alzheimer's Disease by Activating Autophagy-Related Signaling Pathways [0.03%]
通过激活自噬相关信号通路利用高压氧疗法改善阿尔茨海默病患者的认知功能
B Li,H Li,H Chen et al.
B Li et al.
To investigate the impact of hyperbaric oxygen therapy (HBOT) on the cognitive function of mice with Alzheimer's disease (AD), while also identifying the cellular pathways associated with autophagy involved in the treatment. Twenty-four APP...
Berberine Exerts Neuroprotective Effects in Alzheimer's Disease by Switching Microglia M1/M2 Polarization Through PI3K-AKT Signaling [0.03%]
小檗碱通过PI3K-AKT信号转导通路切换小胶质细胞M1/M2极化，在阿尔茨海默病中发挥神经保护作用
Y Hu,P Zhang,X Wang
Y Hu
Berberine (BBR), a small molecule protoberberine isoquinoline alkaloid, is easy to cross the blood-brain barrier and is a potential drug for neurodegenerative diseases. Here, we explored the role and molecular mechanism of BBR in Alzheimer'...