Angelica sinensis: Botany, Traditional Uses, Phytochemistry, Pharmacology, Safety, and Applications [0.03%]
当归：植物学、传统应用、化学成分、药理作用、安全性及应用前景
Yanjuan Zhang,Zemei Zhu,Xinru Li et al.
Yanjuan Zhang et al.
Angelica sinensis (Oliv.) Diels (A. sinensis), a perennial herb with a medicinal history spanning over two millennia, is widely recognized for its effects in nourishing blood, promoting circulation, regulating menstruation, and alleviating ...
Targeting the Nrf2 Signaling Pathway: A Review of Traditional Chinese Medicine for Alzheimer's Disease [0.03%]
针对阿尔茨海默病治疗的 NRF2 信号通路及中医药研究进展综述
Ming Liu,Hang Hong,Xingxing Zhang et al.
Ming Liu et al.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily characterized by [Formula: see text]-amyloid (A[Formula: see text]) deposition, Tau protein hyperphosphorylation, and chronic neuroinflammation. Current pharmaco...
Ginsenosides in Liver Fibrosis: Pharmacological Actions and Therapeutic Potential [0.03%]
人参皂苷在肝纤维化中的药理作用和治疗潜力
Na Li,Fanghang Ye,Fei Yu et al.
Na Li et al.
Liver fibrosis (LF) represents a critical pathological stage in the progression of various chronic liver diseases, and is characterized by the sustained activation of hepatic stellate cells (HSCs) and excessive deposition of extracellular m...
Astragaloside IV Ameliorates Diabetic Kidney Disease via Inhibiting MAPK Pathway and Alleviating Metabolic Dysregulation [0.03%]
毛蕊花糖苷IV通过抑制MAPK通路及改善代谢失调治疗糖尿病肾病
You Wang,Guang-Rui Huang,Bao-Sheng Zhao et al.
You Wang et al.
Diabetic kidney disease (DKD) is a severe diabetic microvascular complication with a complex pathogenesis and progression driven by renal fibrosis and inflammation. As a condition, DKD imposes a heavy clinical burden. Astragaloside IV (AS-I...
Ephedrae Herba and Ephedrine on Nervous System: A Comprehensive Review of Pharmacology and Neurotoxicity [0.03%]
麻黄与麻黄碱对神经系统的影响：药理及神经毒性的全面综述
Junying Li,Rui Zheng,Xingjiang Xiong et al.
Junying Li et al.
Since Ephedra Herba (ephedra) and its major alkaloid ephedrine were prohibited as dietary supplements due to their adverse effects on the cardiovascular and central nervous system (CNS), most studies have focused on their amphetamine-like e...
Icariin from Epimedium: A Multi-Target Natural Flavonoid and Its Multi-Disease Therapeutic Potential [0.03%]
淫羊藿中(icaritin)：一种多靶点天然黄酮及其潜在的治疗多种疾病的功效
Shiyuan Li,Huiyu Wang,Sujuan Ding et al.
Shiyuan Li et al.
Icariin (ICA), an isoprenylated flavonoid glycoside extracted from the traditional Chinese herb Epimedium, is the primary bioactive constituent of that herb. ICA has been documented to have a diverse array of bioactivities which encompass a...
Curcumin Metabolites and Metabolic Health: Insights into Regulatory Mechanisms of Glucose and Lipid Homeostasis [0.03%]
姜黄素代谢产物与代谢健康：葡萄糖和脂质稳态调控机制的见解
Fanfei Liu,Chongyan Zhao,Qi Zhang et al.
Fanfei Liu et al.
Curcumin, a bioactive compound and vibrant yellow pigment extracted from the rhizome of Curcuma longa, has a well-established safety profile and demonstrates defined pharmacological activities. These activities include regulating glucose an...
Decoding Herbal Medicine: Machine Learning-Driven Insights into Structural Identification and Pharmacological Research [0.03%]
基于机器学习的草药解码：结构识别与药理研究的新视野
Yumo Bie,Yang Yang,Pan Wang
Yumo Bie
Herbal medicine is indispensable and crucial to many healthcare systems. Its therapeutic value arises from diverse plant-derived compounds with potential pharmacological activities. This review summarizes recent advances in applying artific...
Progress of Traditional Chinese Medicine in Targeting Ferroptosis to Combat Cerebral Ischemia-Reperfusion Injury [0.03%]
中医药靶向铁死亡防治脑缺血再灌注损伤研究进展
Jianhui Li,Annan Liu,Wei Gao et al.
Jianhui Li et al.
Cerebral ischemia-reperfusion injury (CIRI) often results in significant morbidity and mortality. The effectiveness of current reperfusion therapies is hindered by substantial secondary damage, which highlights the need for novel molecular ...
Andrographolide Suppresses Head and Neck Squamous Cell Carcinoma Progression via EGR1-ACSL4 Axis-Mediated Ferroptosis [0.03%]
andrographolide通过EGR1-ACSL4轴介导的铁死亡抑制头颈鳞状细胞癌进展
Guo Cheng,Xin Zhu,Chenping Zhang
Guo Cheng
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive malignancy with high rates of recurrence and metastasis that result in poor clinical outcomes. Ferroptosis, an iron-dependent, lipid peroxidation-driven regulated cell dea...