Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development [0.03%]
Zhifeng Wu,Yueyue Teng,Shengchao Huang et al.
Zhifeng Wu et al.
Breast cancer remains one of the most prevalent malignancies among women worldwide. Although advances in multimodal therapies have markedly improved clinical outcomes, recurrence and metastasis continue to pose major challenges. Vasculogeni...
Yonghuang Tan,Jun Ma,Jiangli Zhou et al.
Yonghuang Tan et al.
Lung cancer remains the primary cause of cancer-related mortality worldwide. BUD23, also known as Williams-Beuren syndrome critical region 22, is an rRNA methyltransferase involved in ribosome maturation and RNA methylation. It has been rep...
Clinical features and outcomes of peripheral T-cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases [0.03%]
Meng-Xue Ma,Ya-Li Zhang,Li-Na Xing et al.
Meng-Xue Ma et al.
Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is the most common histological subtype of PTCL. PTCL-NOS has a relatively low incidence, and its pathogenesis and mechanisms of drug resistance remain unclear, leading to laggi...
[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF-κB pathway [0.03%]
[表达关注]通过抑制NF-κB途径诱导 gambogic酸在食管鳞状细胞系中诱导凋亡的作用
Wen-Yue Liu,Xu Wu,Cheng-Quan Liao et al.
Wen-Yue Liu et al.
Jingjing Zhang,Rupu Zhao,Pengjie Yang et al.
Jingjing Zhang et al.
The Krüppel-like family (KLF) are important transcriptional regulators that have important, context-specific roles in gastrointestinal (GI) malignancies. Their roles are very heterogeneous; each of the KLF members may play tumor-suppressiv...
KRAS (G12D)-selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma [0.03%]
选择性KRAS(G12D)抑制剂MRTX1133可抑制卵巢黏液性癌的增殖并差异调节其化疗敏感性
Ryota Watano,Hiroaki Mizukami,Yasushi Saga
Ryota Watano
Ovarian mucinous carcinoma (OMC) is a rare subtype of ovarian cancer characterized by frequent KRAS mutations and a poor response to platinum- and taxane-based chemotherapy, underscoring the need for novel therapeutic strategies. MRTX1133, ...
Thrombospondin-1 triggers calreticulin expression in human mucoepidermoid carcinoma MC-3 cells via the PERK/CHOP pathway [0.03%]
血小板反应蛋白-1通过PERK/CHOP途径触发人黏液表皮样癌MC-3细胞calreticulin的表达
Shengwei Bao,Yuanyuan Zhu,Lijuan Guo et al.
Shengwei Bao et al.
Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy, accounting for ~30% of all salivary gland malignancies; however, effective treatments for advanced-stage disease remain limited. The induction of immunogenic cell ...
Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review) [0.03%]
乳腺癌中EGFR家族可溶形式的研究进展及其临床意义（综述）
Peng Yang,Xinnong Jiang,Fangguo He
Peng Yang
Breast cancer (BrCa) is the leading cause of cancer death among women worldwide. The epidermal growth factor receptor (EGFR) family, consisting of EGFR/erythroblastic leukemia viral (v-erbB) oncogene homolog (ErbB)1, human epidermal growth ...
Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review) [0.03%]
诺滨海尼在癌症治疗中的作用：多靶点机制、克服药物耐药和转化治疗的新见解(综述)
Yanfang Zhang,Qingcai Li,Wenbin Yu et al.
Yanfang Zhang et al.
Nobiletin, a polymethoxyflavone derived from Citrus peels, has emerged as a promising multi-target anticancer agent. The present review consolidates recent advances elucidating the efficacy of nobiletin in suppressing tumor growth across di...
Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single-cell and bulk RNA-sequencing [0.03%]
利用单细胞和批量RNA测序的综合分析揭示Tregs在肺癌中的预后和免疫治疗作用
Hongwei He,Zhiming Xiao,Jijun Xue et al.
Hongwei He et al.
The infiltration of regulatory T cells (Tregs) in lung adenocarcinoma (LUAD) is associated with a poor prognosis. The present study aimed to explore the potential function of Treg marker genes in prognosis and immunotherapy using the transc...