Clinicopathological features and therapeutic advances in primary pulmonary lymphoepithelioma-like carcinoma (Review) [0.03%]
原发性肺淋巴上皮样癌的临床病理特征及治疗进展（综述）
Yong Chen,Yonglin Yu,Xiaoju Chen
Yong Chen
Primary pulmonary lymphoepithelioma-like carcinoma (PPLELC) is a rare subtype of non-small cell lung cancer, the clinicopathological features and molecular mechanisms of which are markedly different from those of other lung cancer subtypes....
Superior cancer detection with transperineal biopsy in patients with an elevated prostate-specific antigen level and a PI-RADS score of 3-4: A retrospective cohort study [0.03%]
前列腺特异性抗原水平升高且PI-RADS评分为3-4的患者经会阴活检诊断前列腺癌更优：一项回顾性队列研究
Jun Zhang,Hui Zheng
Jun Zhang
The early and accurate detection of prostate cancer remains pivotal for improving clinical outcomes. The present study aimed to compare the cancer detection rates (CDRs) and safety profiles of transperineal (TP) vs. transrectal (TR) prostat...
SUMOylation inhibitor TAK-981 suppresses proliferation and induces apoptosis in SK-UT-1B uterine leiomyosarcoma cells [0.03%]
SUMOylation抑制剂TAK-981可抑制SK-UT-1B子宫平滑肌肉瘤细胞的增殖并诱导其凋亡
Hosouk Joung,Hyunju Liu
Hosouk Joung
Uterine leiomyosarcoma (Ut-LMS) is an aggressive smooth muscle malignancy with limited therapeutic options and a poor prognosis, underscoring the need for new molecularly-targeted therapies. TAK-981 (subasumstat), a selective inhibitor of s...
Androgen receptor drives lenvatinib resistance in hepatocellular carcinoma through transcriptional activation of EIF3I and a downstream ceRNA axis [0.03%]
雄激素受体通过转录激活EIF3I和下游ceRNA轴驱动肝细胞癌耐药性
Changfeng Liu,Bing Zhang,Ye Jin et al.
Changfeng Liu et al.
Lenvatinib resistance is a notable clinical challenge in advanced hepatocellular carcinoma (HCC). Androgen receptor (AR) upregulation has been associated with poor prognosis and high invasiveness, particularly in AR-high HCC, yet its specif...
FBXL5 depletion as a novel strategy against osteosarcoma: Evidence for MEK/ERK inhibition and enhanced therapeutic sensitivity [0.03%]
靶向破坏FBXL5作为治疗骨肉瘤的新策略：抑制MEK/ERK通路及增强化疗敏感性的证据
Yan-Chao Ma,Wen-Ming Zhou,Yong-Qiang Shi et al.
Yan-Chao Ma et al.
Osteosarcoma (OS) is the most common primary malignant bone tumor in adolescents. Despite standard treatments, including surgery and chemotherapy, the 5-year survival rate for metastatic OS remains
[Expression of Concern] Myricetin inhibits migration and invasion of hepatocellular carcinoma MHCC97H cell line by inhibiting the EMT process [0.03%]
表达关注：通过抑制上皮间质转化过程抑制黄酮类化合物Myricetin对肝癌MHCC97H细胞系迁移侵袭的影响
Hongxin Ma,Lei Zhu,Jingna Ren et al.
Hongxin Ma et al.
Identification of neoadjuvant chemoradiotherapy resistance-associated proteins in locally advanced rectal cancer: A pilot study [0.03%]
局部晚期直肠癌新辅助放化疗耐药相关蛋白的识别：一项初步研究
Jiang-Yi He,Yan Dong,Can Chen et al.
Jiang-Yi He et al.
Neoadjuvant chemoradiotherapy (nCRT) resistance in locally advanced rectal cancer (LARC) leads to worse outcomes. The present pilot study aimed to identify candidate proteins associated with resistance to nCRT. Data-independent acquisition ...
Overexpression of EZH2 is associated with clinicopathological parameters and poor prognosis in gliomas [0.03%]
EZH2过表达与胶质瘤的临床病理参数及不良预后相关
Can Peng,Wei Chen,Jun Yang et al.
Can Peng et al.
The histone methyltransferase enhancer of zeste homolog 2 (EZH2), which is primarily localized in the nucleus, mediates Polycomb repressive complex activity by trimethylating lysine 27 of histone H3 (H3K27me3), thereby leading to transcript...
Methylation of the BMP6, BRCA1, ESR2, GSTP1 and TIMP3 genes in Mexican women with breast cancer and benign disease [0.03%]
墨西哥乳腺癌和良性疾病患者中BMP6、BRCA1、ESR2、GSTP1和TIMP3基因的甲基化状况研究
Samantha Rebeca de la Torre-Guzmán,Andrea Marlene García Muro,Brenda Pelayo-Chávez et al.
Samantha Rebeca de la Torre-Guzmán et al.
Breast cancer (BC) is the main cause of cancer-related mortality in women and is influenced by genetic, environmental and lifestyle factors. The inactivation of tumor suppressor genes, such as bone morphogenetic protein 6 (BMP6), breast can...
Pathological fracture of primary lymphoma of bone: A case report on diagnosis and novel surgical management [0.03%]
原发骨淋巴瘤的病理性骨折诊断及手术治疗一例报告
Duc Thanh Tran,Van Khanh Nguyen,Tran Quang Sang Nguyen et al.
Duc Thanh Tran et al.
Primary lymphoma of bone (PLB) is an uncommon malignancy, representing ~4-5% of primary malignant bone tumors and 1% of all malignant lymphomas. Diffuse large B-cell lymphoma (DLBCL) is the most common subtype, accounting for ~80% of cases,...
Case Reports
Oncology letters. 2026 Jun 19;32(2):362. DOI:10.3892/ol.2026.15717 2026