Risk Factors for Niraparib-induced Severe Anemia in Japanese Patients With Ovarian Cancer: A Multicenter Study [0.03%]
尼拉帕利致日本卵巢癌患者严重贫血的危险因素:一项多中心研究
Yuki Ozawa,Hiromu Tanigawa,Tatsuhiro Fujimiya et al.
Yuki Ozawa et al.
Background/aim: Niraparib is an effective maintenance therapy after platinum-based chemotherapy for ovarian cancer. However, niraparib-induced anemia, particularly when severe, often leads to treatment discontinuation and...
Observational Study
Anticancer research. 2026 May;46(5):2887-2897. DOI:10.21873/anticanres.18167 2026
Real-world Delivery and Outcomes of Intravesical BCG for Non-muscle-invasive Bladder Cancer [0.03%]
卡介苗膀胱灌注治疗非肌层浸润性膀胱癌的真实世界实施及疗效分析
Nobuki Furubayashi,Jiro Tsujita,Azusa Takayama et al.
Nobuki Furubayashi et al.
Background/aim: Intravesical bacillus Calmette-Guérin (BCG) therapy remains the standard adjuvant treatment for high-risk non-muscle-invasive bladder cancer (NMIBC), yet real-world maintenance delivery is frequently inco...
Observational Study
Anticancer research. 2026 May;46(5):2599-2608. DOI:10.21873/anticanres.18140 2026
Prognostic Impact of the Geriatric Nutritional Risk Index in Elderly Patients With Colorectal Cancer [0.03%]
老年结直肠癌患者老年营养风险指数的预后价值
Yasunobu Kobayashi,Yasuhiro Takano,Anna Fukushima et al.
Yasunobu Kobayashi et al.
Background/aim: The aim of this study was to assess the prognostic impact of the Geriatric Nutritional Risk Index in elderly patients with colorectal cancer and to evaluate the utility of this new system. ...
6-O-Carboxypropyl-α-Tocotrienol Enhances the Anticancer Effects of Bortezomib Without Suppressing NRF1 and NRF3 in Colorectal Cancer Cells [0.03%]
6-O-羧基丙基-α-托考三烯醇在结直肠癌细胞中增强硼替佐米的抗癌作用而不抑制NRF1和NRF3
Kyota Ishii,Tomohiro Yano
Kyota Ishii
Background/aim: Bortezomib, a proteasome inhibitor, exhibits limited efficacy against colorectal cancer (CRC); therefore, strategies to enhance bortezomib sensitivity in CRC are required. Previous studies have reported th...
Postoperative Changes in Nutritional Status and their Impact on Post-recurrence Prognosis After Pancreatoduodenectomy in Patients With Biliary Tract Carcinoma: An Age-stratified Analysis [0.03%]
胆道癌患者胰十二指肠切除术后营养状况变化及其对复发后预后影响的年龄分层分析
Wataru Izumo,Ryo Saito,Hidetake Amemiya et al.
Wataru Izumo et al.
Background/aim: To clarify postoperative changes in nutritional status and their impact on post-recurrence prognosis after pancrexatoduodenectomy in patients with biliary tract carcinoma based on age and recurrence status...
Sulfasalazine an Inhibitor of System xC - (Cystine/glutamate Antiporter), Combined With Recombinant Methioninase, Inhibits Both Cancer and Normal Cells, Suggesting Lack of Cancer Selectivity of Cysteine Restriction [0.03%]
硫酸盐沙利度胺是一种System xC-(胱氨酸/谷氨酸抗转运蛋白)抑制剂,与重组亚甲基转移酶联合应用,可同时抑制癌细胞和正常细胞,表明胱氨酸限制缺乏癌症选择性
Jinsoo Kim,Qinghong Han,Shukuan Li et al.
Jinsoo Kim et al.
Background/aim: Sulfasalazine (SSZ), an inhibitor of xCT/system xC -, blocks cystine uptake and depletes intracellular glutathione, leading to ferroptotic cell death. Recombinant methioninase (rMETase) targets methionine ...
Pregabalin for Opioid-resistant Neuropathic Pain in Bone Metastases [0.03%]
普瑞巴林治疗骨转移性疼痛患者的阿片类药物难治性神经痛疗效观察
Kiyohiro Sakai,Yasuko Ikeda-Sakai,Hiromichi Matsuoka
Kiyohiro Sakai
Background/aim: To evaluate the tolerability and effectiveness of pregabalin for the treatment of opioid-resistant neuropathic pain associated with bone metastases in patients with cancer. ...
Laparotomy After Total Pelvic Exenteration: Current Status and Techniques for Ileal Conduit Preservation [0.03%]
盆腔全切术后开腹术的现状及回肠导管保存技术
Koji Komori,Takashi Kinoshita,Akira Ouchi et al.
Koji Komori et al.
Background/aim: Advances in chemotherapy have shifted the treatment paradigm for colorectal cancer from surgical intervention to medical treatment. We report the outcomes of laparotomy following total pelvic exenteration ...
Robotic-assisted Distal Pancreatectomy Is Associated With Significant Reduction of Morphine Consumption for the Treatment of Acute Postoperative Pain [0.03%]
机器人辅助远端胰腺切除术与急性术后止痛阿片类药物使用量显著降低相关
Amelie F Kruse,Andreas Andreou,Haluk Morgul et al.
Amelie F Kruse et al.
Background/aim: Minimal-invasive techniques have been increasingly performed to treat pancreatic lesions. We evaluated the differences between open and robotic approach for distal pancreatectomy (DP) in terms of postopera...
Gossypol Inhibits GLI3-dependent SHH Signaling to Selectively Target SPOP-deficient Breast Cancer Cells [0.03%]
Gossypol通过抑制GLI3依赖的SHH信号通路选择性靶向SPOP缺陷型乳腺癌细胞
Patricia Augustine,Jazmin Chavarria,Marieke Burleson
Patricia Augustine
Background/aim: Breast cancer remains one of the leading causes of cancer-related mortality among women. The molecular heterogeneity of breast cancer, reflected in its numerous subtypes with variable responses to conventi...