Ginsenoside Rg3 potentiates cisplatin antitumor activity while mitigating nephrotoxicity through SIRT1‑mediated suppression of the NLRP3 inflammasome [0.03%]
Ginsenoside Rg3通过SIRT1介导的NLRP3炎性小体抑制增强顺铂的抗肿瘤作用并减轻肾毒性
Jinghui Zhai,Yueming Zhang,Jiawei Gong et al.
Jinghui Zhai et al.
Lung cancer is one of the most common causes of cancer‑related mortality worldwide, with cisplatin (CP) being a key chemotherapeutic agent. However, its use is limited by nephrotoxicity and drug resistance. Ginsenoside Rg3 (Rg3) has antica...
Identification of diagnostic markers for diabetic kidney disease by weighted gene co‑expression network analysis and machine learning [0.03%]
通过加权基因共表达网络分析和机器学习鉴定糖尿病肾脏疾病的诊断标志物
Qiming Xu,Chunjing Xu,Ziyang Liu et al.
Qiming Xu et al.
Diabetic kidney disease (DKD) represents a major complication associated with diabetes mellitus, notably contributing to patient morbidity and mortality. However, early diagnosis of DKD remains challenging due to the lack of clear diagnosti...
Bone‑origin repair in diabetic foot ulcers: Mechanisms of callus formation and endocrine effects in healing (Review) [0.03%]
糖尿病足溃疡骨源性修复：骨痂形成机制与内分泌影响作用（综述）
Sen Chen,Xiaofei Cui
Sen Chen
Diabetic foot ulcers (DFUs) represent a severe complication of diabetes mellitus, affecting ~1/3 of diabetic patients during their lifetime and imposing substantial clinical and economic burdens globally. While conventional understanding at...
Spatial hepatology: Decoding liver zonation for metabolic and regenerative therapeutics (Review) [0.03%]
空间肝学：解码代谢和再生治疗的肝脏区域化（综述）
Guiqing Chen,Hongyan Jia,Kai Zhao et al.
Guiqing Chen et al.
The integration of spatial omics and single‑cell technologies has redefined liver zonation as a dynamic regulator of regeneration, extending beyond its traditional role in metabolic compartmentalization. This progress has given rise to the...
Hepatic p38γ exacerbates acetaminophen‑induced acute liver injury via PI3K/Akt‑dependent mechanisms [0.03%]
肝p38γ通过PI3K/Akt依赖机制加重乙酰氨基酚诱导的急性肝损伤
Hui Fang,Min Shu,Jiaju Wang et al.
Hui Fang et al.
An acetaminophen (APAP) overdose can result in acute and chronic liver injury. Thus, the discovery of biomarkers for the management of APAP‑induced liver injury is crucial from a therapeutic standpoint. As one of the four isoforms of p38 m...
Shiyan Song,Yong Tan
Shiyan Song
Following the publication of the above article, an interested reader drew to the authors' attention that, concerning the images showing the green fluorescence of granulosa cells in Fig. 5 on p. 874, the images selected for Fig. 5B and C wer...
Published Erratum
International journal of molecular medicine. 2026 Jul;58(1):179. DOI:10.3892/ijmm.2026.5850 2026
Mengtian Tang,Zhongjian Zhu,Huaxin Duan et al.
Mengtian Tang et al.
Rab proteins are core regulators of vesicle trafficking during membrane transport. As key members of this family, Rab27 comprises two functionally distinct isoforms, Rab27a and Rab27b, and participates in the regulation of exosome secretion...
Pharmacological activity, molecular mechanisms and therapeutic potential of erianin (Review) [0.03%]
eryianin的药理活性、分子机制和治疗潜力（综述）
Chengyi Ming,Ni Zhu,You Yu et al.
Chengyi Ming et al.
As a natural active ingredient extracted from Dendrobium chrysotoxum, erianin shows multi‑target regulatory characteristics. The present review aimed to summarize the physiological effects, molecular mechanisms and therapeutic potential of...
[Corrigendum] Induction of cardiomyocyte‑like cells from hair follicle cells in mice [0.03%]
小鼠毛囊细胞诱导分化成类心肌细胞的修正意见
Yong-Hee Kim,Bang-Jin Kim,Seok-Man Kim et al.
Yong-Hee Kim et al.
Following the publication of the above article, an interested reader drew to the authors' attention that, concerning the micrographic images shown in Fig. 3B on p. 2234, the 'OP9' and 'MEF' data panels showed an overlapping section, such th...
Published Erratum
International journal of molecular medicine. 2026 Jul;58(1):186. DOI:10.3892/ijmm.2026.5857 2026
miR‑223‑3p promotes microglial lactylation and M1 polarization via the FBXW7/Notch1/Hes1/SIRT1 axis [0.03%]
miR‑223‑3p通过FBXW7/Notch1/Hes1/SIRT1轴促进小胶质细胞乳酰化和M1极化
Xiaoyu Wang,Lin Song,Jiafeng Wang et al.
Xiaoyu Wang et al.
Neuroinflammation is a hallmark of Alzheimer's disease (AD) and is closely linked to microglial M1 polarization. In the present study, miR‑223‑3p was identified as a critical regulator of microglial metabolic reprogramming. Analyses of Ge...