Arsenic exposure and skin cancer: Mechanisms, clinical evidence and public health implications (Review) [0.03%]
砷暴露与皮肤癌:机制、临床证据和公共卫生影响(综述)
Dimitrios A Andreikos,Michael Aschner,Dimitrios C Ziogas et al.
Dimitrios A Andreikos et al.
Skin is among the most frequent sites of cancer diagnosis, and the global incidence of skin cancer continues to rise despite extensive public health initiatives and preventive strategies. Arsenic, a ubiquitous environmental metalloid classi...
Targeting glutathione metabolism for tumor radiosensitization (Review) [0.03%]
靶向半胱氨酸代谢以增强肿瘤放疗敏感性(综述)
Haonan Xu,Meng Du,Xiaowen Liang et al.
Haonan Xu et al.
Radiotherapy represents a cornerstone treatment modality in oncology and primarily mediates tumor cell death through the generation of reactive oxygen species (ROS). Nevertheless, elevated glutathione (GSH) levels within tumor cells can sca...
Moderate downregulation of NDUFA13 promotes cardiomyocytes proliferation and heart regeneration through the glycolysis/c‑Myc/ Ccnd1 axis [0.03%]
中度下调NDUFA13通过糖酵解/c-Myc/Ccnd1轴促进心肌细胞增殖和心脏再生
Ying Gao,Ningjing Qian,Junyan Jin et al.
Ying Gao et al.
The poor prognosis of heart diseases is largely attributable to the limited proliferative capacity of cardiomyocytes. Cardiomyocyte proliferation and heart regeneration has garnered increasing attention, with a focus on the identification o...
Oridonin ameliorates ulcerative colitis by regulating the PI3K/AKT/mTOR signaling pathway to activate autophagy [0.03%]
通过调节PI3K/AKT/mTOR信号通路诱导自噬来改善溃疡性结肠炎作用机制研究:岩白菜素的抗溃疡性结肠炎效应及其分子机理研究
Zhongxing Miao,Baohong Liu,Xingzhi Zhou et al.
Zhongxing Miao et al.
The present study aimed to investigate the therapeutic effects and underlying mechanism of oridonin (ORI) in ulcerative colitis (UC) using the lipopolysaccharide (LPS)‑induced macrophage inflammatory model in vitro and the dextran sulfate ...
Effects of exercise‑derived extracellular vesicles: Epigenetic regulatory mechanisms and protective roles (Review) [0.03%]
运动衍生外泌体的影响:表观遗传调节机制和保护作用(综述)
Xinxin Zhang,Biao Zhang
Xinxin Zhang
Exercise exerts broad and sustained effects on metabolic homeostasis and overall physiology. However, the circulating mediators connecting localized exercise responses to coordinated systemic adaptation remain poorly defined, particularly t...
[Retracted] Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome [0.03%]
[classified撤回][小鼠脂多糖诱导的急性呼吸窘迫综合征中]经典树突状细胞调节急性肺部炎症和损伤
Lang Li,Liang Dong,Dan Zhao et al.
Lang Li et al.
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, regarding the lung tissue images shown in Fig. 5B on p. 624, the 'FLT3L+AARDS' and 'DMSO+AARDS' panels contained an overlapping sect...
[Corrigendum] (‑)‑Epigallocatechin‑3‑gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions [0.03%]
(-)-表没食子儿茶素-3-没食子酸酯通过抑制氧化应激和细胞凋亡减轻糖尿病大鼠心肌缺血再灌注损伤及高糖诱导的H9c2心肌细胞损伤的修正意见
Yang Wu,Zhong-Yuan Xia,Bo Zhao et al.
Yang Wu et al.
Following the publication of the above article, an interested reader drew to the authors' attention that, concerning the Masson trichrome‑stained sections of left ventricles shown in Fig. 6A on p. 395, a portion of the panel representing t...
Published Erratum
International journal of molecular medicine. 2026 Aug;58(2):218. DOI:10.3892/ijmm.2026.5889 2026
Melatonin ameliorates circadian rhythm disruption induced erectile dysfunction by inhibiting oxidative stress mediated pyroptosis via Nrf2/HO‑1 axis [0.03%]
褪黑素通过Nrf2/HO-1轴抑制氧化应激介导的焦亡改善节律紊乱诱导的勃起功能障碍
Qingtao Yang,Wei Li,Qi Yu et al.
Qingtao Yang et al.
Circadian rhythm disruption (CRD) is highly prevalent in modern society and contributes to numerous disorders, including erectile dysfunction (ED). Melatonin (MT) possesses well‑established functions in regulating circadian rhythm and demo...
Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress [0.03%]
狼疮性肾炎候选药物_withaferin A通过Pon1介导的抗氧化作用发挥肾脏保护效应
Miao Xue,Junshuai Feng,Xiaorong Mao
Miao Xue
Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE). It is characterized by autoantibody deposition and immune complex formation within the kidney, leading to progressive nephron loss and end‑stage renal di...
Spatial architecture of immunometabolism: Mitochondrial‑organelle interfaces in immune signaling (Review) [0.03%]
免疫代谢的空间架构:免疫信号传导中的线粒体-细胞器界面(综述)
Yaping Wu,Hao Yu,Ling Xia et al.
Yaping Wu et al.
Metabolic reprogramming is fundamental to immune cell function, yet the spatial architecture that organizes these metabolic states remains incompletely defined. Rather than functioning as isolated bioenergetic units, mitochondria act as spa...