Role of extracellular matrix in liver fibrosis regression and regeneration (Review) [0.03%]
细胞外基质在肝纤维化消退和再生中的作用(综述)
Yuanzhi Zhou,Zeyuan Qiang,Yang Duan et al.
Yuanzhi Zhou et al.
The extracellular matrix (ECM), a critical component of the cellular microenvironment, is intimately linked to normal physiological functions and pathological alterations in tissues. In the liver, ECM homeostasis governs key processes inclu...
[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects [0.03%]
表达关注:通过发挥HO-1介导的抗炎和抗氧化作用,芹茋能够保护小鼠免受急性重症胰腺炎侵害
Jie Xiong,Kezhou Wang,Chunxiao Yuan et al.
Jie Xiong et al.
Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the histological images shown in Fig. 2A on p. 117, the 'NC/3 h' and 'NC/6 h' data panels contained an overlapping se...
Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies [0.03%]
能量压力激活AMPK抑制神经退行性蛋白病中的铁死亡
Yuanyuan Yong,Yuxin Hu,Qian Feng et al.
Yuanyuan Yong et al.
Ferroptosis, an iron‑dependent and lipid peroxidation‑driven form of regulated cell death, has emerged as a key contributor to neuronal degeneration in protein misfolding disorders. However, how cellular energy metabolism modulates ferrop...
Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review) [0.03%]
空间转录组学在肿瘤免疫微环境分析中的作用(综述)
Jialin Jiang,Xinyu Tu,Yi Cao et al.
Jialin Jiang et al.
The tumor immune microenvironment plays a decisive role in tumor initiation, progression and therapeutic response. Spatial transcriptomics (ST) enables comprehensive analysis of the whole transcriptome or specific gene sets while preserving...
[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency [0.03%]
循环微小核糖核酸谱型和鉴定直接靶向联合垂体激素缺乏症患儿PROP1基因的miR-593和miR-511
Yanyan Hu,Qian Wang,Zengmin Wang et al.
Yanyan Hu et al.
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, regarding the western blot data shown in Fig. 4B on p. 364, the GAPDH blots were shown to be the same for the experiments performed ...
Published Erratum
International journal of molecular medicine. 2026 Oct;58(4):270. DOI:10.3892/ijmm.2026.5941 2026
Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo [0.03%]
巴西宁通过在体内外增强eIF5A的hypusination并抑制AMPK/mTOR介导的自噬/凋亡轴来缓解甲基乙二醛诱导的内皮损伤
Yu Liang,Jinxiang Chen,Haiyang Li et al.
Yu Liang et al.
Methylglyoxal (MGO), a glycolytic metabolic byproduct and major precursor of advanced glycation end products (AGEs), accumulates and is critically involved in diabetes, particularly in diabetic vascular complications. In endothelial cells (...
Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review) [0.03%]
动脉粥样硬化中翻译后修饰的作用、机制和治疗潜力(综述)
Xiaoxiang Xu,Fei Ma,Wei Yu
Xiaoxiang Xu
Atherosclerosis (AS) is the principal pathological basis of cardiovascular disease and develops through the coordinated progression of endothelial dysfunction, lipid accumulation, macrophage foam‑cell formation, vascular smooth muscle cell...
Effects of cuproptosis and its application in inflammatory bowel disease (Review) [0.03%]
铜死亡的效应及其在炎症性肠病中的应用(综述)
Li Chen,Francis Atim Akanyibah,Jing Guan et al.
Li Chen et al.
Inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, is a common, recurring, chronic intestinal inflammatory illness that is considered to be impacted by the immune system, gut microbiota and genetic fact...
Gut‑bone metabolites: SCFAs, polyamines and microbial metabolomics in osteoporosis risk and therapy (Review) [0.03%]
肠道-骨骼代谢物:短链脂肪酸、多胺和微生物组代谢组学在骨质疏松症风险及治疗中的作用(综述)
Fuchao Chen,Jingyue Sun,Xiao Wang
Fuchao Chen
Osteoporosis (OP), a major global skeletal disorder characterized by reduced bone mass and increased fracture risk, is increasingly understood through the lens of the gut‑bone axis. The present review critically synthesizes mechanistic and...
circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction [0.03%]
环状RNA_013145-miR-185-5p-RhoA轴:糖尿病引起的勃起功能障碍病理生理中的新机制
Wenhan Huang,Xin Lv,Jiahua Qian et al.
Wenhan Huang et al.
Diabetes mellitus‑induced erectile dysfunction (DMED) is a common diabetic complication characterized by endothelial dysfunction and corpus cavernosum (CC) remodeling. Although circular RNAs (circRNAs) have been implicated in diabetic vasc...