[Retracted] Songorine suppresses cell growth and metastasis in epithelial ovarian cancer via the Bcl‑2/Bax and GSK3β/β‑catenin signaling pathways [0.03%]
宋碱通过Bcl-2/Bax和GSK3β/β-catenin信号通路抑制上皮性卵巢癌的细胞生长和转移(已撤回)
Hongxia Zhang,Ruifeng Dong,Ping Zhang et al.
Hongxia Zhang et al.
Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, in addition to the duplication of data within Fig. 3A (the 0 h wound‑healing assay experimental panels), certain of the immuno...
CXCL1 in triple‑negative breast cancer: Mechanisms, challenges, and therapeutic opportunities (Review) [0.03%]
三阴性乳腺癌中的CXCL1:机制、挑战与治疗机遇(综述)
Hiba Al Sayegh,Zahraa Assi,Amjad Kanaan et al.
Hiba Al Sayegh et al.
Triple negative breast cancer (TNBC) is an aggressive BC subtype with limited therapeutic options and poor clinical outcomes. This subtype accounts for 15‑20% of all BC cases and contributes to nearly 40% of BC mortalities. The chemokine C...
Platycodin D sensitizes head and neck squamous cell carcinoma to cisplatin by inducing autophagy arrest [0.03%]
北豆根苷D通过诱导自噬阻滞增强头颈鳞癌细胞对顺铂的敏感性
Minji Bae,Min Kyeong Lee,Mi Gyeong Jeong et al.
Minji Bae et al.
Head and neck squamous cell carcinoma (HNSCC) is one of the most common malignancies worldwide. Cisplatin, a widely used chemotherapeutic agent, exerts its anticancer effect by inducing DNA damage, and inhibiting transcription and replicati...
[Expression of Concern] c‑Fos/ERK promotes the progression from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma [0.03%]
c-Fos/ERK促进胰腺上皮内瘤变向胰导管腺癌进展表达关注公告
Lei You,Xiaoxia Ren,Yongxing Du et al.
Lei You et al.
Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the histological images shown in Fig. 2B on p. 3416, the ῾Caerulein 7 days' and 'Caerulein 14 days' panels showed an...
Advances in the application of frailty scoring in the diagnosis and management of elderly patients with multiple myeloma (Review) [0.03%]
脆弱度评分在老年多发性骨髓瘤患者诊断和管理中的应用进展(综述)
Junlun Liu,Danyu Li,Chao Li et al.
Junlun Liu et al.
Multiple myeloma (MM) is a hematological malignancy that disproportionately affects elderly populations, with age being a key risk factor for disease progression and adverse outcomes. Frailty, a multifaceted geriatric syndrome characterized...
Knockdown of CCT2 inhibits the malignant progression of hepatocellular carcinoma cells by impairing STAT3 activation [0.03%]
CCT2敲低通过抑制STAT3激活抑制肝癌细胞恶性进展
Chao Li,Lei Yang,Yudong Zhang et al.
Chao Li et al.
Hepatocellular carcinoma (HCC) is an aggressive liver malignancy, the molecular mechanisms underlying the progression of which are not fully understood. As a component of the chaperonin‑containing tailless complex polypeptide 1 (TCP1) ring...
[Retracted] Growth and differentiation factor‑9 promotes adhesive and motile capacity of prostate cancer cells by up‑regulating FAK and Paxillin via Smad dependent pathway [0.03%]
生长分化因子-9通过Smad依赖通路上调FAK和Paxillin促进前列腺癌细胞黏附及运动能力(英文版)
Sivan M Bokobza,Lin Ye,Howard G Kynaston et al.
Sivan M Bokobza et al.
Subsequently to the publication of the above article, a concerned reader drew the Editor's attention to the fact that certain of the protein bands shown in lanes 1, 3 and 4 for the Smad3 experiments for the western blots in Fig. 5A on p. 16...
Role of iron and TfR1 in the application of high‑dose ascorbate against pancreatic cancer [0.03%]
铁和TfR1在高剂量维生素C对抗胰腺癌中的作用
Alban Piotrowsky,Christian Leischner,Hendrik Schmieder et al.
Alban Piotrowsky et al.
Pancreatic cancer remains one of the deadliest tumor diseases with an urgent need for new therapy options. At the same time, the use of high‑dose vitamin C in cancer treatment has been investigated for decades. Despite promising in vitro a...
Cellular and inflammatory characteristics of patient‑derived glioblastoma organoids during in vitro cultivation [0.03%]
取自患者的胶质母细胞瘤类器官在体外培养过程中的细胞及炎症特征分析
Jessica Nojszewski,Nils Oliver Schröder,Jacqueline Clüver et al.
Jessica Nojszewski et al.
Glioblastomas are characterized by extensive intra‑ and intertumoral heterogeneity, which drives their rapid invasive growth and frequent recurrence. As a result, prognosis remains poor, and developing effective treatments continues to be ...
ACSBG1‑driven lipid reprogramming unveiled: A fatty acid metabolism‑associated prognostic model for lung adenocarcinoma [0.03%]
ACSBG1驱动的脂质重构被揭秘:一种与肺腺癌脂肪酸代谢相关的预后模型
Panxin Hu,Anan Li
Panxin Hu
Lung adenocarcinoma (LUAD) remains a leading cause of cancer‑associated mortality with limited prognostic biomarkers. Fatty acid metabolism (FAM) reprogramming serves a pivotal role in tumor progression; however, the functional importance ...