Hypoxic CAF studies unveil PTHrP‑vitamin D‑RAS axis as pivotal in the CAF [0.03%]
低氧CAF研究揭示PTHrP-维生素D-RAS轴在CAF中的重要作用
Shoichiro Nakajo,Mamoru Uemura,Hiroshi Kusafuka et al.
Shoichiro Nakajo et al.
Cancer‑associated fibroblasts (CAFs) play critical roles in the tumor microenvironment (TME); however, their characteristics under hypoxic conditions remain incompletely understood. The aim of the present study was to investigate the prope...
[Retracted] miR‑24‑3p regulates bladder cancer cell proliferation, migration, invasion and autophagy by targeting DEDD [0.03%]
[撤回]miR-24-3p通过靶向DEDD调节膀胱癌细胞增殖、迁移、侵袭和自噬
Guoqiang Yu,Zhaohui Jia,Zhongling Dou
Guoqiang Yu
Following the publication of the above article, a concerned reader drew to the Editor's attention that, regarding the cell migration assay experiments shown in Fig. 3B, the 'miR‑24‑3p inhibitor' panels that had been included to represent ...
[Expression of Concern] 5‑Azacytidine inhibits the proliferation of bladder cancer cells via reversal of the aberrant hypermethylation of the hepaCAM gene [0.03%]
表达关注：5-氮杂胞苷通过逆转hepaCAM基因异常高甲基化来抑制膀胱癌细胞增殖
Xiaorong Wang,E Chen,Xue Yang et al.
Xiaorong Wang et al.
Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the immunohistochemical images shown in Fig. 1A on p. 1377, the 'DNMT3A' and 'DNMT3B' images for the 'BN' row of data...
HMGB3: A pivotal orchestrator of therapy resistance and cancer stemness in human malignancies (Review) [0.03%]
HMGB3：在人类恶性肿瘤中调控治疗耐药性和癌症干细胞性的关键协调者（综述）
Ju Zhang,Yifan Sun,Lanyu Wang et al.
Ju Zhang et al.
High mobility group box 3 (HMGB3) acts as an essential participator in fundamental biological processes, including transcriptional regulation, chromatin remodeling and DNA repair. HMGB3 is highly expressed and functionally essential during ...
[Retracted] Ultrasound‑targeted microbubble destruction‑mediated overexpression of Sirtuin 3 inhibits the progression of ovarian cancer [0.03%]
[撤回]超声靶向微泡破坏介导Sirtuin 3过表达抑制卵巢癌进展
Li Cheng,Dongmei Zhang,Wei Yan
Li Cheng
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the data showing the results of EdU assay experiments in Fig. 2C on p. 5 were strikingly similar to data that had either a...
T cell fate regulation in EBV‑associated nasopharyngeal carcinoma (Review) [0.03%]
EB病毒感染的鼻咽癌中T细胞命运调节（综述）
Liuyang Zhang,Shun Ding,Dongzhui Chen et al.
Liuyang Zhang et al.
Nasopharyngeal carcinoma, a malignancy associated with Epstein‑Barr virus, presents a complex immune editing landscape in which T cell fate determination carries out a central role. T cell metabolic exhaustion, Epstein‑Barr virus antigen ...
Role of CHD4 in tumor progression, DNA damage response and treatment resistance (Review) [0.03%]
CHD4在肿瘤进展、DNA损伤反应和治疗抵抗中的作用(综述)
Shuo Li,Quan Ma,Keying Lian et al.
Shuo Li et al.
Chromodomain helicase DNA‑binding protein 4 (CHD4) is a core adenosine triphosphate (ATP)‑dependent chromatin‑remodeling factor of the nucleosome‑remodeling and deacetylase (NuRD) complex. It plays a crucial role in chromatin structure ...
ZBTB7A promotes malignant phenotypes in ovarian cancer through transcriptional activation of CRLF1 [0.03%]
ZBTB7A通过CRLF1转录激活促进卵巢癌恶性表型
Xiaobai Hao,Yu Chen
Xiaobai Hao
Ovarian cancer (OV) remains the most lethal gynecological malignancy, owing to late‑stage diagnosis, high metastatic potential and limited therapeutic efficacy. Although the transcription factor zinc finger and BTB domain‑containing 7A (Z...
[Retracted] Roles of the SNHG7/microRNA‑9‑5p/DPP4 ceRNA network in the growth and 131I resistance of thyroid carcinoma cells through PI3K/Akt activation [0.03%]
[撤回]通过PI3K / Akt激活调控甲状腺癌细胞生长和131碘抗性中SNHG7 / microRNA-9-5p / DPP4 ceRNA网络的作用机制研究
Wanzhi Chen,Jichun Yu,Rong Xie et al.
Wanzhi Chen et al.
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that there appeared to be a series of internally duplicated groupings/repeated patternings of cells within various of the panels in the DP...
MS4322 is a selective protein arginine methyltransferase 5 degrader with antitumor effects in cervical cancer cells [0.03%]
MS4322是一种选择性蛋白精氨酸甲基转移酶5降解剂，在宫颈癌细胞中具有抗肿瘤作用
Rui Luo,Jingping Chen,Zhaojie Chen et al.
Rui Luo et al.
Drug therapy serves a key role in the treatment of cervical cancer, which is one of the most common types of solid tumor in female patients. Therefore, it is important to seek more effective and less toxic therapies. Protein arginine methyl...