Advances in immunotherapy and targeted therapy for nasopharyngeal carcinoma: Current progress and combined approaches (Review) [0.03%]
免疫疗法和靶向治疗鼻咽癌的研究进展：目前的进展与联合应用（综述）
Zhen Yang,Huajun Liu,Meilin Chen et al.
Zhen Yang et al.
Nasopharyngeal carcinoma (NPC), a malignancy of the head and neck closely associated with Epstein‑Barr virus (EBV) infection, is highly prevalent in southern China and Southeast Asia. Traditional treatments such as radiotherapy and chemoth...
Natalia Podhorska,Jan Hrabeta,Marie Belhajova et al.
Natalia Podhorska et al.
Chemoresistance is a major cause of cancer therapy failure. Increasing evidence points to the importance of histone lysine demethylase function, whose dysregulation has been described in several types of cancer. KDM5, a family of histone ly...
Hypoxia‑induced miR‑135b‑5p promotes neuroendocrine differentiation of prostate cancer cells through HIF1AN‑HIF1α axis [0.03%]
缺氧诱导的miR‑135b‑5p通过HIF1AN‑HIF1α轴促进前列腺癌细胞神经内分泌分化
Pampana Sandhya Venkata Lakshmi,Jagrati Parashar,Biswajit Biswas et al.
Pampana Sandhya Venkata Lakshmi et al.
Neuroendocrine prostate cancer (NEPC) is a highly aggressive subtype of prostate cancer (PCa), associated with poor prognosis and resistance to androgen receptor (AR)‑targeted therapies. Hypoxia is a well‑established driver of lineage pla...
NR4A1 mediates chemotherapy‑induced senescence via the PI3K/AKT pathway in gastric cancer cells [0.03%]
NR4A1通过PI3K/AKT途径介导化疗诱导的胃癌细胞衰老
Tingyu Zhang,Yue Wang,Jiuna Zhang et al.
Tingyu Zhang et al.
Gastric cancer (GC) remains among the cancers with extremely high morbidity and mortality rates worldwide, and chemotherapy resistance limits its therapeutic efficacy. Therapy‑induced senescence (TIS) is vital for inducing chemotherapy res...
[Retracted] Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP‑9 [0.03%]
人类抗原R敲低抑制乳腺癌细胞的生长和侵袭并影响cyclin D1和MMP-9的表达被撤回）
Zhu Yuan,Andrew J Sanders,Lin Ye et al.
Zhu Yuan et al.
Following the publication of the above paper, a concerned reader drew to the Editor's attention that, for the RT‑qPCR experiments shown in Fig. 2A on p. 240, data which were intended to show the results of experiments performed in two diff...
Impact of the intratumoral resident microbiome on the immune microenvironment of malignant tumors (Review) [0.03%]
肿瘤细胞内菌群与肿瘤免疫微环境相互作用的机制及其临床意义的研究进展
Han Na Oh,Hoon Hur
Han Na Oh
Advances in cancer research have highlighted the importance of tumor‑intrinsic factors, including tumor type, immune environment, immunogenicity, metabolic demands and the intratumoral microbiome. Together, these factors have reshaped the ...
Suppressive role of SCN4B in the epithelial‑mesenchymal transition of lung adenocarcinoma [0.03%]
SCN4B在肺癌上皮间质转化中的抑制作用
Mengnan Guo,He Li,Zhifang Zhao et al.
Mengnan Guo et al.
The poor prognosis and high mortality rate of non‑small cell lung cancer are largely driven by its aggressive migratory and invasive behavior. Epithelial‑mesenchymal transition (EMT) is a central mechanism conferring these malignant trait...
Regorafenib and Nifuroxazide exert enhanced suppression of hepatocellular carcinoma by inhibiting STAT3 and immune remodeling [0.03%]
雷戈菲尼联合硝呋磺酸钠通过抑制STAT3和免疫重塑增强对肝细胞癌的抑制作用
Kun Li,Jinwei Chen,Zhi Zheng et al.
Kun Li et al.
Regorafenib, a multi‑kinase inhibitor, has limited efficacy in hepatocellular carcinoma (HCC) due to dose‑-dependent toxicity. The present study explored whether low‑dose Regorafenib combined with Nifuroxazide exerts enhanced anti‑tumor...
[Retracted] miR‑218 suppresses cardiac myxoma proliferation by targeting myocyte enhancer factor 2D [0.03%]
[撤回]:miR-218通过靶向肌细胞增强因子2D抑制心脏黏液瘤增殖
Quanxing Cao,Pingshuan Dong,Yanyu Wang et al.
Quanxing Cao et al.
Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that the GAPDH and MEF21 protein bands shown in the western blots in Fig. 2C on p. 2608 were strikingly similar to data appearing in ...
Liquid biopsy in malignant primary bone tumors: Clinical applications of circulating tumor DNA and circulating tumor cells for diagnosis, prognosis and treatment monitoring (Review) [0.03%]
恶性原发性骨肿瘤的液体活检技术：循环肿瘤DNA和循环肿瘤细胞在诊断、预后及疗效监测中的临床应用（综述）
Bin Tian,Xuesong Chen,Jiang Zheng et al.
Bin Tian et al.
Liquid biopsy, which involves the detection of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs), is revolutionizing the management of osteosarcoma, Ewing sarcoma and chondrosarcoma by enabling noninvasive diagnosis, risk str...