KMO downregulation promotes hepatocellular carcinoma growth via 3‑HAA‑mediated mitochondrial mass and function imbalances [0.03%]
KMO下调通过3-HAA介导的线粒体质量与功能失衡促进肝癌生长
Ming Liu,Xintong Zhang,Yanfen Hu et al.
Ming Liu et al.
Kynurenine (Kyn) 3‑monooxygenase (KMO) is a key enzyme of the tryptophan (Try)‑Kyn pathway and is located on the outer membrane of mitochondria. Notably, it has not yet been elucidated as to whether KMO is involved in hepatocellular carci...
Regulatory networks of HIFs in tumor‑infiltrating immune cells: From molecular mechanisms to therapeutic implications (Review) [0.03%]
缺氧诱导因子在肿瘤浸润免疫细胞中的调控网络：从分子机制到治疗意义（综述）
Chaoqun Li,Chenge Qin,Xingchen Li et al.
Chaoqun Li et al.
Hypoxic tumor microenvironment (TME) is a common occurrence in the development of solid tumors, which activates hypoxia‑inducible factors (HIFs) and their downstream signaling pathways in cancer cells to facilitate tumor progression and im...
Unveiling sex differences in pancreatic ductal adenocarcinoma: Current evidence and future directions (Review) [0.03%]
揭示胰腺导管腺癌性别差异的当前证据和未来方向（综述）
Sophie Rauschenberg,Elisabeth Orgler-Gasche,Didem Karakas Zeybek et al.
Sophie Rauschenberg et al.
Pancreatic ductal adenocarcinoma (PDAC) is the seventh leading cause of cancer‑related death worldwide in both men and women. While sex‑specific differences are increasingly recognized as critical determinants of health and disease, parti...
[Retracted] LTBP2 promotes the migration and invasion of gastric cancer cells and predicts poor outcome of patients with gastric cancer [0.03%]
LTBP2促进胃癌细胞迁移侵袭并提示胃癌患者预后不良
Jun Wang,Wen-Jia Liang,Guang-Tao Min et al.
Jun Wang et al.
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell cell migration and invasion assay data shown in Fig. 5A on p. 1895 were strikingly similar to data in an art...
Circ72309 modulates gemcitabine metabolism and gemcitabine sensitivity in pancreatic cancer: Serum Circ72309 levels as a potential predictor of treatment response [0.03%]
Circular RNAcirc72309通过调节吉西他滨的代谢影响胰腺癌细胞对吉西他滨敏感性：血液中circ72309水平作为预测吉西他滨疗效标志物的潜在价值
Naoko Sekiguchi,Hidenori Takahashi,Shogo Kobayashi et al.
Naoko Sekiguchi et al.
Circular RNAs (circRNAs) are associated with various biological features of cancer, including chemosensitivity and the structural characteristics of circRNAs indicate their potential as liquid biomarkers. Gemcitabine is a cornerstone treatm...
[Retracted] uPAR and cathepsin B knockdown inhibits radiation‑induced PKC integrated integrin signaling to the cytoskeleton of glioma‑initiating cells [0.03%]
[uPAR和CTSH基因沉默抑制胶质瘤干细胞的PKC整合素信号转导通路]
Kiranmai Alapati,Sreelatha Gopinath,Rama Rao Malla et al.
Kiranmai Alapati et al.
Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the wound healing assay data shown in Fig. 2D, a pair of the data panels appeared to be overlapping, such that the da...
PTPN18 functions as a tumor suppressor in breast cancer by negatively regulating cyclin E [0.03%]
PTPN18通过抑制cyclin E发挥乳腺癌的抑癌作用
Na Zhang,Tao Wang,Bin Bai et al.
Na Zhang et al.
Protein tyrosine phosphatase non‑receptor 18 (PTPN18) is widely expressed in breast cancer (BC) cell lines. Additionally, high levels of PTPN18 facilitate an improved overall survival and prognosis in patients with BC. However, the effects...
[Retracted] Suppression of the death gene BIK is a critical factor for resistance to tamoxifen in MCF‑7 breast cancer cells [0.03%]
[BIK死亡基因的抑制是乳腺癌MCF-7细胞耐药的重要因素
Rubí Viedma-Rodriguez,Luis Arturo Baiza-Gutman,Alejandro García-Carrancá et al.
Rubí Viedma-Rodriguez et al.
Following the publication of the above paper, a concerned reader drew to the Editor's attention that, in Fig. 6, the same data appeared to have been included in three of the flow cytometric plots featured in this figure (for the Non‑treate...
Targeted therapies for urothelial carcinoma: From FGFR inhibitors to next‑generation antibody-drug conjugates (Review) [0.03%]
尿路上皮癌的靶向治疗：从FGFR抑制剂到下一代抗体药物偶联物（综述）
Jinping Du,Hao Shen,Tongwei Zeng et al.
Jinping Du et al.
Treatment of urothelial carcinoma (UC), particularly in metastatic or cisplatin‑ineligible patients, remains challenging because of limited durable responses to conventional chemotherapy and immune checkpoint inhibitors. Recent advances in...
Exosomal circRNAs in hepatocellular carcinoma: Implications for the development and therapeutic resistance of hepatocellular carcinoma (Review) [0.03%]
肝细胞癌中exo-circRNA的含义：exo-circRNA在肝癌发生及耐药中的作用(综述)
Zhiyao Liu,Yuqiao Wang,Yali Wang et al.
Zhiyao Liu et al.
Hepatocellular carcinoma (HCC) is the predominant type of primary liver cancer, with high morbidity and mortality rates globally, ranking it among the leading causes of cancer‑related death worldwide. Despite notable advancements in HCC tr...