N H Kim,V Nadithe,M Elsayed et al.
N H Kim et al.
Upon activation, T cells of various subsets are the most important mediators in cell-mediated immune responses. Activated T cells play an important role in immune system related diseases such as chronic inflammatory diseases, viral infectio...
Quantifying Tight Junction Disruption Caused by Biomimetic pH-Sensitive Hydrogel Drug Carriers [0.03%]
生物启发的pH响应性药物输送水凝胶破坏紧密连接定量研究
Omar Z Fisher,Nicholas A Peppas
Omar Z Fisher
Facilitation of protein transport across biomimetic polymers and carriers used in drug delivery is a subject of major importance in the field of oral delivery. Quantitative immunofluorescence of epithelial tight junctions can be a valuable ...
T G Farmer Jr,T F Edgar,N A Peppas
T G Farmer Jr
A pharmacokinetic model is proposed to describe the glucoregulatory process. The model describes the dynamics of glucose, amino acids, and fatty acids, as well as both the hormonal actions and dynamics of insulin, glucagon, epinephrine, and...
M K Pastuszka,J A Mackay
M K Pastuszka
Tools to selectively and reversibly control gene expression are useful to study and model cellular functions. When optimized, these cellular switches can turn a protein's function "on" and "off" based on cues designated by the researcher. T...
Prodrug and conjugate drug delivery strategies for improving HIV/AIDS therapy [0.03%]
用于改善艾滋病治疗的前药和缀合药物递送策略
M S Palombo,Y Singh,P J Sinko
M S Palombo
Despite the wide variety of highly potent anti-HIV drugs that have been developed and made available in clinical practice over the years, eradication of HIV infection has not been achieved. Currently, HIV infection and AIDS are thought to b...