Laura Chacon Machado,Joseph E Peters
Laura Chacon Machado
Tn7 family transposons are mobile genetic elements known for precise target site selection, with some co-opting CRISPR-Cas systems for RNA-guided transposition. We identified a novel group of Tn7-like transposons in Cyanobacteria that prefe...
A genome-wide study of ruminants uncovers two endogenous retrovirus families recently active in goats [0.03%]
反刍动物的全基因组研究揭示了山羊中两种近期活跃的内源性逆转录病毒家族
Marie Verneret,Caroline Leroux,Thomas Faraut et al.
Marie Verneret et al.
Background: Endogenous retroviruses (ERV) are traces of ancestral retroviral germline infections that constitute a significant portion of mammalian genomes and are classified as LTR-retrotransposons. The exploration of th...
Targeted detection of endogenous LINE-1 proteins and ORF2p interactions [0.03%]
内源性LINE-1蛋白及ORF2p相互作用的靶向检测
Mathias I Nielsen,Justina C Wolters,Omar G Rosas Bringas et al.
Mathias I Nielsen et al.
Background: Both the expression and activities of LINE-1 (L1) retrotransposons are known to occur in numerous cell-types and are implicated in pathobiological contexts such as aging-related inflammation, autoimmunity, and...
FishPi: a bioinformatic prediction tool to link piRNA and transposable elements [0.03%]
FishPi：一个用于链接piRNA和转座元件的生物信息预测工具
Alice M Godden,Benjamin Rix,Simone Immler
Alice M Godden
Background: Piwi-interacting RNAs (piRNA)s are non-coding small RNAs that post-transcriptionally affect gene expression and regulation. Through complementary seed region binding with transposable elements (TEs), piRNAs pr...
SINE retrotransposons import polyadenylation signals to 3'UTRs in dog (Canis familiaris) [0.03%]
反转座子SINE将多腺苷酸化信号导入狗(Canis familiaris)的3′非翻译区（3'UTR）中
Jessica D Choi,Lelani A Del Pinto,Nathan B Sutter
Jessica D Choi
Background: Messenger RNA 3' untranslated regions (3'UTRs) control many aspects of gene expression and determine where the transcript will terminate. The polyadenylation signal (PAS) AAUAAA (AATAAA in DNA) is a key regula...
Controlling and controlled elements: highlights of the year in mobile DNA research [0.03%]
控制与被控元素：移动DNA研究的年度亮点
Irina R Arkhipova,Kathleen H Burns,Pascale Lesage
Irina R Arkhipova
Analysis of pericentromere composition and structure elucidated the history of the Hieracium alpinum L. genome, revealing waves of transposable elements insertions [0.03%]
外卫基因组历史分析揭示了多年生黄花属植物转座子插入的多次浪潮
Alexander Belyayev,Begoña Quirós de la Peña,Simon Villanueva Corrales et al.
Alexander Belyayev et al.
Background: The centromere is one of the key regions of the eukaryotic chromosome. While maintaining its function, centromeric DNA may differ among closely related species. Here, we explored the composition and structure ...
International congress on transposable elements (ICTE 2024) in Saint Malo: breaking down transposon waves and their impact [0.03%]
圣马洛国际转座元件大会（ICTE 2024）：分解转座子浪潮及其影响
Pascale Lesage,Emilie Brasset,Gael Cristofari et al.
Pascale Lesage et al.
From April 20 to 23, 2024, three hundred ten researchers from around the world gathered in Saint-Malo, France, at the fourth International Congress on Transposable Elements (ICTE 2024), to present their most recent discoveries on transposab...
Association of hyperactivated transposon expression with exacerbated immune activation in systemic lupus erythematosus [0.03%]
系统性红斑狼疮中转座子表达过度活化与免疫激活加剧的相关性研究
Frank Qingyun Wang,Xiao Dang,Huidong Su et al.
Frank Qingyun Wang et al.
Background: Systemic Lupus Erythematosus (SLE) is a complex autoimmune disorder, and transposable elements (TEs) have been hypothesized to play a significant role in its development. However, limited research has explored...
Herui Liao,Yanni Sun,Shujun Ou
Herui Liao
Genome annotation is an important but challenging task. Accurate identification of short interspersed nuclear elements (SINEs) is particularly difficult due to their lack of highly conserved sequences. AnnoSINE is state-of-the-art software ...