Heads or tails: L1 insertion-associated 5' homopolymeric sequences [0.03%]
巧合的还是必然的：L1插入相关的5'同聚核苷酸序列
Thomas J Meyer,Deepa Srikanta,Erin M Conlin et al.
Thomas J Meyer et al.
Background: L1s are one of the most successful autonomous mobile elements in primate genomes. These elements comprise as much as 17% of primate genomes with the majority of insertions occurring via target primed reverse t...
Immunity of replicating Mu to self-integration: a novel mechanism employing MuB protein [0.03%]
Mu复制时的自我整合免疫性：一种新的利用MuB蛋白的机制
Jun Ge,Zheng Lou,Rasika M Harshey
Jun Ge
We describe a new immunity mechanism that protects actively replicating/transposing Mu from self-integration. We show that this mechanism is distinct from the established cis-immunity mechanism, which operates by removal of MuB protein from...
James A Shapiro
James A Shapiro
Scientific history has had a profound effect on the theories of evolution. At the beginning of the 21st century, molecular cell biology has revealed a dense structure of information-processing networks that use the genome as an interactive ...
Epigenetic histone modifications of human transposable elements: genome defense versus exaptation [0.03%]
人类转座元件的表观遗传组蛋白修饰：基因组防御与征用之间的权衡取舍关系
Ahsan Huda,Leonardo Mariño-Ramírez,I King Jordan
Ahsan Huda
Background: Transposition is disruptive in nature and, thus, it is imperative for host genomes to evolve mechanisms that suppress the activity of transposable elements (TEs). At the same time, transposition also provides ...
Welcome to mobile DNA [0.03%]
移动DNA期刊封面文章集锦
Nancy L Craig,Thomas H Eickbush,Daniel F Voytas
Nancy L Craig
Extrachromosomal circles of satellite repeats and 5S ribosomal DNA in human cells [0.03%]
人类细胞中染色体外的卫星重复序列和5S核糖DNA圈圈
Sarit Cohen,Neta Agmon,Olga Sobol et al.
Sarit Cohen et al.
Background: Extrachomosomal circular DNA (eccDNA) is ubiquitous in eukaryotic organisms and was detected in every organism tested, including in humans. A two-dimensional gel electrophoresis facilitates the detection of ec...
The structure, organization and radiation of Sadhu non-long terminal repeat retroelements in Arabidopsis species [0.03%]
拟南芥属中Sadhu非长末端重复逆转录元件的结构、组织和转座拷贝分布特征分析
Sanjida H Rangwala,Eric J Richards
Sanjida H Rangwala
Background: Sadhu elements are non-autonomous retroposons first recognized in Arabidopsis thaliana. There is a wide degree of divergence among different elements, suggesting that these sequences are ancient in origin. Her...
Detecting variable (V), diversity (D) and joining (J) gene segment recombination using a two-colour fluorescence system [0.03%]
采用双色荧光系统检测可变(V)、多样性(D)和连接(J)基因片段的重组事件
Gina B Scott,Erika A de Wynter,Graham P Cook
Gina B Scott
Background: Diversity of immunoglobulins and the T cell antigen receptors is achieved via the recombination activating gene (RAG)-mediated rearrangement of variable (V), diversity (D) and joining (J) gene segments, and th...