Prevalence of SOS-mediated control of integron integrase expression as an adaptive trait of chromosomal and mobile integrons [0.03%]
SOS诱导的染色体和可移动整合子整合酶表达调控的适应性特征的流行性研究
Guillaume Cambray,Neus Sanchez-Alberola,Susana Campoy et al.
Guillaume Cambray et al.
Background: Integrons are found in hundreds of environmental bacterial species, but are mainly known as the agents responsible for the capture and spread of antibiotic-resistance determinants between Gram-negative pathoge...
Reliable transgene-independent method for determining Sleeping Beauty transposon copy numbers [0.03%]
一种可靠且无需转基因的方法用于测定Sleeping Beauty转位子拷贝数
Orsolya Kolacsek,Virág Krízsik,Anita Schamberger et al.
Orsolya Kolacsek et al.
Background: The transposon-based gene delivery technique is emerging as a method of choice for gene therapy. The Sleeping Beauty (SB) system has become one of the most favored methods, because of its efficiency and its ra...
Plant centromeric retrotransposons: a structural and cytogenetic perspective [0.03%]
植物端粒重复序列的研究：结构和细胞遗传学观点
Pavel Neumann,Alice Navrátilová,Andrea Koblížková et al.
Pavel Neumann et al.
Background: The centromeric and pericentromeric regions of plant chromosomes are colonized by Ty3/gypsy retrotransposons, which, on the basis of their reverse transcriptase sequences, form the chromovirus CRM clade. Despi...
André Larouche,Paul H Roy
André Larouche
Background: Integrons are genetic elements able to integrate and disseminate genes as cassettes by a site-specific recombination mechanism. These elements contain a gene coding for an integrase that carries out recombinat...
Characterization of a synthetic human LINE-1 retrotransposon ORFeus-Hs [0.03%]
人合成LINE-1逆转座子ORFeus-Hs的表征
Wenfeng An,Lixin Dai,Anna Maria Niewiadomska et al.
Wenfeng An et al.
Long interspersed elements, type 1(LINE-1, L1) are the most abundant and only active autonomous retrotransposons in the human genome. Native L1 elements are inefficiently expressed because of a transcription elongation defect thought to be ...
Reverse transcription of the pFOXC mitochondrial retroplasmids of Fusarium oxysporum is protein primed [0.03%]
青霉属oxysporium菌中以蛋白质为引物的pFOXC线粒体逆转录噬质粒的合成机制
Jeffrey T Galligan,Sarah E Marchetti,John C Kennell
Jeffrey T Galligan
Background: The pFOXC retroplasmids are small, autonomously replicating DNA molecules found in mitochondria of certain strains of the filamentous fungus Fusarium oxysporum and are among the first linear genetic elements s...
The expanding universe of transposon technologies for gene and cell engineering [0.03%]
基因和细胞工程的转座子技术版图正在不断扩张
Zoltán Ivics,Zsuzsanna Izsvák
Zoltán Ivics
Transposable elements can be viewed as natural DNA transfer vehicles that, similar to integrating viruses, are capable of efficient genomic insertion. The mobility of class II transposable elements (DNA transposons) can be controlled by con...
Maria I Pajunen,Tiina S Rasila,Lotta J Happonen et al.
Maria I Pajunen et al.
Background: Completed genome projects have revealed an astonishing diversity of transposable genetic elements, implying the existence of novel element families yet to be discovered from diverse life forms. Concurrently, s...
Regulators of ribonucleotide reductase inhibit Ty1 mobility in saccharomyces cerevisiae [0.03%]
调控核糖核苷酸还原酶的调节物可抑制 Saccharomyces cerevisiae 中 Ty1 的移动性
John P O&#x;Donnell,Marie Gehman,Jill B Keeney
John P O&#x;Donnell
Background: Ty1 is a long terminal repeat retrotransposon of Saccharomyces cerevisiae, with a replication cycle similar to retrovirus replication. Structurally, Ty1 contains long terminal repeat (LTR) regions flanking the...
Feedback inhibition of L1 and alu retrotransposition through altered double strand break repair kinetics [0.03%]
L1和Alu逆转录通过改变的双链断裂修复动力学对其反馈抑制
Nicholas A Wallace,Victoria P Belancio,Zach Faber et al.
Nicholas A Wallace et al.
Background: Cells adapt to various chronic toxic exposures in a multitude of ways to minimize further damage and maximize their growth potential. Expression of L1 elements in the human genome can be greatly deleterious to...