Alu expression in human cell lines and their retrotranspositional potential [0.03%]
人类细胞系中的Alu表达及其逆转录转座潜能
Andrew J Oler,Stephen Traina-Dorge,Rebecca S Derbes et al.
Andrew J Oler et al.
Background: The vast majority of the 1.1 million Alu elements are retrotranspositionally inactive, where only a few loci referred to as 'source elements' can generate new Alu insertions. The first step in identifying the ...
Rita Rebollo,Sharareh Farivar,Dixie L Mager
Rita Rebollo
Background: Functional regulatory sequences are present in many transposable element (TE) copies, resulting in TEs being frequently exapted by host genes. Today, many examples of TEs impacting host gene expression can be ...
R2 and R2/R1 hybrid non-autonomous retrotransposons derived by internal deletions of full-length elements [0.03%]
由全长元件内部缺失衍生的R2和R2 / R1非自主逆转座子
Danna G Eickbush,Thomas H Eickbush
Danna G Eickbush
Background: R2 is a non-long terminal repeat (non-LTR) retrotransposable element that inserts site specifically into the 28S genes of the ribosomal (r)RNA gene loci. Encoded at the 5' end is a ribozyme that generates the ...
Orangutan Alu quiescence reveals possible source element: support for ancient backseat drivers [0.03%]
类人猿Alu沉默揭示可能来源元素：支持古代搭便车现象
Jerilyn A Walker,Miriam K Konkel,Brygg Ullmer et al.
Jerilyn A Walker et al.
Background: Sequence analysis of the orangutan genome revealed that recent proliferative activity of Alu elements has been uncharacteristically quiescent in the Pongo (orangutan) lineage, compared with all previously stud...
Identification of basepairs within Tn5 termini that are critical sfor H-NS binding to the transpososome and regulation of Tn5 transposition [0.03%]
识别Tn5末端中基对对于H-NS结合转位体和调控Tn5转位至关重要的位点
Crystal R Whitfield,Brian H Shilton,David B Haniford
Crystal R Whitfield
Background: The H-NS protein is a global regulator of gene expression in bacteria and can also bind transposition complexes (transpososomes). In Tn5 transposition H-NS promotes transpososome assembly in vitro and disrupti...
Towards a more accurate annotation of tyrosine-based site-specific recombinases in bacterial genomes [0.03%]
向更准确地注释细菌基因组中的酪氨酸位点特异性重组酶发展
Rob Van Houdt,Raphael Leplae,Gipsi Lima-Mendez et al.
Rob Van Houdt et al.
Background: Tyrosine-based site-specific recombinases (TBSSRs) are DNA breaking-rejoining enzymes. In bacterial genomes, they play a major role in the comings and goings of mobile genetic elements (MGEs), such as temperat...
Thibaud S Boutin,Arnaud Le Rouzic,Pierre Capy
Thibaud S Boutin
Background: Many theoretical models predicting the dynamics of transposable elements (TEs) in genomes, populations, and species have already been proposed. However, most of them only focus on populations of sexual diploid...
Copy number variation of ribosomal DNA and Pokey transposons in natural populations of Daphnia [0.03%]
自然群体中核糖体DNA拷贝数变异和Pokey转座子的研究
Shannon Hc Eagle,Teresa J Crease
Shannon Hc Eagle
Background: Despite their ubiquity and high diversity in eukaryotic genomes, DNA transposons are rarely encountered in ribosomal DNA (rDNA). In contrast, R-elements, a diverse group of non-LTR retrotransposons, specifical...
Brian Green,Christiane Bouchier,Cécile Fairhead et al.
Brian Green et al.
Background: Transposons, segments of DNA that can mobilize to other locations in a genome, are often used for insertion mutagenesis or to generate priming sites for sequencing of large DNA molecules. For both of these use...
The predominantly selfing plant Arabidopsis thaliana experienced a recent reduction in transposable element abundance compared to its outcrossing relative Arabidopsis lyrata [0.03%]
自交为主的植物拟南芥近期的转座子丰度相比于其异交近缘种萎缩了
Nicole de la Chaux,Takashi Tsuchimatsu,Kentaro K Shimizu et al.
Nicole de la Chaux et al.
Background: Transposable elements (TEs) are major contributors to genome evolution. One factor that influences their evolutionary dynamics is whether their host reproduces through selfing or through outcrossing. According...