David A Ray,Heidi Jt Pagan,Roy N Platt nd et al.
David A Ray et al.
Background: Short interspersed elements (SINEs) have a powerful influence on genome evolution and can be useful markers for phylogenetic inference and population genetic analyses. In this study, we examined survey sequenc...
Steven Zimmerly,Cameron Semper
Steven Zimmerly
Present in the genomes of bacteria and eukaryotic organelles, group II introns are an ancient class of ribozymes and retroelements that are believed to have been the ancestors of nuclear pre-mRNA introns. Despite long-standing speculation, ...
Genome-wide comparison of Asian and African rice reveals high recent activity of DNA transposons [0.03%]
亚洲稻和非洲稻的基因组对比揭示了DNA转座子的高近期活性
Stefan Roffler,Thomas Wicker
Stefan Roffler
Background: DNA (Class II) transposons are ubiquitous in plant genomes. However, unlike for (Class I) retrotransposons, only little is known about their proliferation mechanisms, activity, and impact on genomes. Asian and...
Transposable elements in a clade of three tetraploids and a diploid relative, focusing on Gypsy amplification [0.03%]
三个多倍体及其二倍体近缘物种的转座元件群体动态分析——以Gypsy科反转座子为例的研究
Mathieu Piednoël,Aretuza Sousa,Susanne S Renner
Mathieu Piednoël
Background: Polyploidization can activate specific transposable elements, leading to their accumulation. At the same time, the preferential loss of repetitive elements in polyploids may be central to diploidization. The p...
HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues [0.03%]
赫尔巴尔文病毒K(HML-2)回文和np9转录物并非仅存在于疾病组织中，在许多正常人类组织中也存在这些转录物
Katja Schmitt,Kristina Heyne,Klaus Roemer et al.
Katja Schmitt et al.
Background: Human endogenous retroviruses of the HERV-K(HML-2) group have been associated with the development of tumor diseases. Various HERV-K(HML-2) loci encode retrovirus-like proteins, and expression of such proteins...
Repeated horizontal transfers of four DNA transposons in invertebrates and bats [0.03%]
无翼DNA转座子在无脊椎动物和蝙蝠中的重复水平转移
Zhou Tang,Hua-Hao Zhang,Ke Huang et al.
Zhou Tang et al.
Background: Horizontal transfer (HT) of transposable elements (TEs) into a new genome is considered as an important force to drive genome variation and biological innovation. However, most of the HT of DNA transposons pre...
Development of a monoclonal antibody specific to the endonuclease domain of the human LINE-1 ORF2 protein [0.03%]
人LINE-1orf2内切酶结构域的单克隆抗体的开发
Mark Sokolowski,Cecily B DeFreece,Geraldine Servant et al.
Mark Sokolowski et al.
Background: LINE-1 (L1) retrotransposons are common occupants of mammalian genomes representing about a fifth of the genetic content. Ongoing L1 retrotransposition in the germ line and somatic tissues has contributed to s...
A droplet digital PCR detection method for rare L1 insertions in tumors [0.03%]
一种检测肿瘤中罕见L1插入的液滴数字PCR方法
Travis B White,Adam M McCoy,Vincent A Streva et al.
Travis B White et al.
Background: The active human mobile element, long interspersed element 1 (L1) currently populates human genomes in excess of 500,000 copies per haploid genome. Through its mobility via a process called target primed rever...
Distinct features of the piRNA pathway in somatic and germ cells: from piRNA cluster transcription to piRNA processing and amplification [0.03%]
piRNA通路在体细胞和生殖细胞中的独特特征：从piRNA簇转录到piRNA加工及放大机制
Emmanuelle Théron,Cynthia Dennis,Emilie Brasset et al.
Emmanuelle Théron et al.
Transposable elements (TEs) are major components of genomes. Their mobilization may affect genomic expression and be a threat to genetic stability. This is why they have to be tightly regulated by a dedicated system. In the reproductive tis...
Tn5 transposition in Escherichia coli is repressed by Hfq and activated by over-expression of the small non-coding RNA SgrS [0.03%]
Hfq抑制和小分子非编码RNA SgrS过表达激活Escherichia coli中Tn5转座作用
Joseph A Ross,Ryan S Trussler,Morgan D Black et al.
Joseph A Ross et al.
Background: Hfq functions in post-transcriptional gene regulation in a wide range of bacteria, usually by promoting base pairing of mRNAs with trans-encoded sRNAs. It was previously shown that Hfq down-regulates Tn10 tran...