Lavanya Rishishwar,Carlos E Tellez Villa,I King Jordan
Lavanya Rishishwar
Background: The human genome contains several active families of transposable elements (TE): Alu, L1 and SVA. Germline transposition of these elements can lead to polymorphic TE (polyTE) loci that differ between individua...
A long terminal repeat retrotransposon of Schizosaccharomyces japonicus integrates upstream of RNA pol III transcribed genes [0.03%]
新型长末端重复序列转座子SjART1的两端是典型的tRNA基因且偏好整合于RNA聚合酶III转录的基因上游区域
Yabin Guo,Parmit Kumar Singh,Henry L Levin
Yabin Guo
Background: Transposable elements (TEs) are common constituents of centromeres. However, it is not known what causes this relationship. Schizosaccharomyces japonicus contains 10 families of Long Terminal Repeat (LTR)-retr...
Identification and characterization of a minisatellite contained within a novel miniature inverted-repeat transposable element (MITE) of Porphyromonas gingivalis [0.03%]
牙龈卟啉单胞菌中新型小型回文重复序列转座子(MITE)的鉴定与特征分析
Brian A Klein,Tsute Chen,Jodie C Scott et al.
Brian A Klein et al.
Background: Repetitive regions of DNA and transposable elements have been found to constitute large percentages of eukaryotic and prokaryotic genomes. Such elements are known to be involved in transcriptional regulation, ...
Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family [0.03%]
瞄准内部敌人：Krüppel关联框锌指蛋白家族在哺乳动物基因组中外源DNA的定点沉默作用
Gernot Wolf,David Greenberg,Todd S Macfarlan
Gernot Wolf
Tandem C2H2-type zinc finger proteins (ZFPs) constitute the largest transcription factor family in animals. Tandem-ZFPs bind DNA in a sequence-specific manner through arrays of multiple zinc finger domains that allow high flexibility and sp...
Comparative paleovirological analysis of crustaceans identifies multiple widespread viral groups [0.03%]
比较甲壳动物古病毒学分析鉴定出多种广泛存在的病毒类群
Gabriel Metegnier,Thomas Becking,Mohamed Amine Chebbi et al.
Gabriel Metegnier et al.
Background: The discovery of many fragments of viral genomes integrated in the genome of their eukaryotic host (endogenous viral elements; EVEs) has recently opened new avenues to further our understanding of viral evolut...
Precise repair of mPing excision sites is facilitated by target site duplication derived microhomology [0.03%]
精确修复mPing切除位点由目标位点重复衍生的微同源序列所促进
David M Gilbert,M Catherine Bridges,Ashley E Strother et al.
David M Gilbert et al.
Background: A key difference between the Tourist and Stowaway families of miniature inverted repeat transposable elements (MITEs) is the manner in which their excision alters the genome. Upon excision, Stowaway-like MITEs...
A host factor supports retrotransposition of the TRE5-A population in Dictyostelium cells by suppressing an Argonaute protein [0.03%]
一个宿主因子通过抑制一种Argonaute蛋白来支持Dictyostelium细胞中TRE5-A族的逆转录转座
Anika Schmith,Thomas Spaller,Friedemann Gaube et al.
Anika Schmith et al.
Background: In the compact and haploid genome of Dictyostelium discoideum control of transposon activity is of particular importance to maintain viability. The non-long terminal repeat retrotransposon TRE5-A amplifies con...
Douglas R Hoen,Glenn Hickey,Guillaume Bourque et al.
Douglas R Hoen et al.
DNA derived from transposable elements (TEs) constitutes large parts of the genomes of complex eukaryotes, with major impacts not only on genomic research but also on how organisms evolve and function. Although a variety of methods and tool...
Min-Jin Han,Chu-Lin Xiong,Hong-Bo Zhang et al.
Min-Jin Han et al.
Background: PHIS transposon superfamily belongs to DNA transposons and includes PIF/Harbinger, ISL2EU, and Spy transposon groups. These three groups have similar DDE domain-containing transposases; however, their coding c...
Repbase Update, a database of repetitive elements in eukaryotic genomes [0.03%]
Repbase Update 反转录转座子及相关重复序列数据库
Weidong Bao,Kenji K Kojima,Oleksiy Kohany
Weidong Bao
Repbase Update (RU) is a database of representative repeat sequences in eukaryotic genomes. Since its first development as a database of human repetitive sequences in 1992, RU has been serving as a well-curated reference database fundamenta...